Results 11 to 20 of about 53,815 (207)
Cholesterol Ester Transfer Protein Inhibitor Review [PDF]
Hospital Pharmacy, 2017 Treatment of blood cholesterol is part of a strategy to lower atherosclerotic cardiovascular (ASCVD) risk. While use of HMG-CoA reductase inhibitors to modify cholesterol levels is the primary means of lowering the risk of an ASCVD event, residual risk remains.
Jerry, Hu, Scot, Walker
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Cholesteryl ester transfer protein inhibitors: from high-density lipoprotein cholesterol to low-density lipoprotein cholesterol lowering agents? [PDF]
Cardiovascular Research, 2021 Abstract Cholesteryl ester transfer protein (CETP) is a liver-synthesized glycoprotein whose main functions are facilitating transfer of both cholesteryl esters from high-density lipoprotein (HDL) particles to apolipoprotein B (apoB)-containing particles as well as transfer of triglycerides from apoB-containing particles to HDL particles.
Nick S Nurmohamed +2 more
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Cholesteryl Ester Transfer Protein Inhibition [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2006 Chemicals / CAS: 2 methylpropanethioic acid s [2 [1 (2 ethylbutyl)cyclohexylcarboxamido]phenyl] ester, 211513-37-0; atorvastatin, 134523-00-5, 134523-03-8; nicotinic acid, 54-86-4, 59-67-6; torcetrapib, 262352-17-0; Carrier Proteins; CETP protein, human; Cholesterol Ester Transfer Proteins; Cholesterol Esters; Cholesterol, HDL; Glycoproteins ...
Rensen, P.C.N., Havekes, L.M.
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Genetic obesity increases pancreatic expression of mitochondrial proteins which regulate cholesterol efflux in BRIN-BD11 insulinoma cells [PDF]
, 2019 Pancreatic β-cells are sensitive to fluctuations in cholesterol content, which can damage the insulin secretion pathway, contributing to the aetiology of type 2 diabetes mellitus.
Caridis, Anna Maria +4 more
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Role of cholesteryl ester transfer protein in reverse cholesterol transport [PDF]
Clinical Cardiology, 1991 Cholesteryl ester transfer protein (CETP) and apolipoprotein E (apo E) play important roles in reverse cholesterol transport in humans. CETP transfers cholesteryl ester (CE) from high-density lipoprotein (HDL) to other lipoproteins, mainly very low-density lipoprotein (VLDL) remnants, which provide a vehicle for the delivery of HDL-derived CE to the ...
R, McPherson, Y, Marcel
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Journal of Lipid Research, 1984 Lecithin:cholesterol acyltransferase (LCAT) and cholesteryl ester (CE) transfer activity accumulate linearly in the recirculated medium of the isolated perfused rabbit liver.
L De Parscau, P E Fielding
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Polyphenol alkyl ester inhibits membrane cholesterol domain formation through an antioxidant mechanism based, in nonlinear fashion, on chain length [PDF]
, 2017 Under conditions of oxidative stress, cholesterol aggregates into discrete membrane bilayer domains that precipitate the formation of extracellular crystals, a hallmark feature of the advanced atheroma in cardiovascular disease.
Durand, Erwann +4 more
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Journal of Lipid Research, 2008 StarD4 protein is a member of the StarD4 subfamily of steroidogenic acute regulatory-related lipid transfer (START) domain proteins that includes StarD5 and StarD6, proteins whose functions remain poorly defined.
Daniel Rodriguez-Agudo +7 more
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Structure and Function of Cholesteryl Ester Transfer Protein in Cholesterol Transferring [PDF]
Biophysical Journal, 2013 Human cholesteryl ester mass can be transferred from atheroprotective high-density lipoproteins (HDL) to atherogenic low-density lipoproteins (LDL) by cholesteryl ester transfer protein (CETP), resulting higher probability of cardiovascular diseases. Finding out the mechanism of CETP in CE transferring would be an important basis and key step toward ...
Zhang, Lei, Tong, Huimin, Ren, Gang
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Reduction in the concentration and activity of plasma cholesteryl ester transfer protein by alcohol.
Journal of Lipid Research, 1992 Plasma cholesteryl esters, synthesized within high density lipoproteins (HDL), may be transferred from HDL particles to other lipoproteins by plasma cholesteryl ester transfer protein (CETP).
M Hannuksela +3 more
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