Results 21 to 30 of about 331,972 (296)
Frontiers in Microbiology, 2021 The intestinal pathogen Clostridioides (C.) difficile is a major cause of diarrhea both in hospitals and outpatient in industrialized countries.
Panagiotis Papatheodorou +11 more
doaj +1 more source
Cholesterol Efflux and Reverse Cholesterol Transport [PDF]
, 2014 Both alterations of lipid/lipoprotein metabolism and inflammatory events contribute to the formation of the atherosclerotic plaque, characterized by the accumulation of abnormal amounts of cholesterol and macrophages in the artery wall. Reverse cholesterol transport (RCT) may counteract the pathogenic events leading to the formation and development of ...
FAVARI, Elda +5 more
openaire +4 more sources
Reverse cholesterol transport and cholesterol efflux in atherosclerosis [PDF]
QJM: An International Journal of Medicine, 2005 Reverse cholesterol transport (RCT) is a pathway by which accumulated cholesterol is transported from the vessel wall to the liver for excretion, thus preventing atherosclerosis. Major constituents of RCT include acceptors such as high-density lipoprotein (HDL) and apolipoprotein A-I (apoA-I), and enzymes such as lecithin:cholesterol acyltransferase ...
R, Ohashi +4 more
openaire +2 more sources
TSPO ligands promote cholesterol efflux and suppress oxidative stress and inflammation in choroidal endothelial cells [PDF]
, 2018 Choroidal endothelial cells supply oxygen and nutrients to retinal pigment epithelial (RPE) cells and photoreceptors, recycle metabolites, and dispose of metabolic waste through the choroidal blood circulation.
Bartholomew, Christopher +4 more
core +1 more source
Transport of apolipoproteins A-I and A-II by human thoracic duct lymph [PDF]
, 1981 The daily transport of human plasma apolipoproteins A-I and A-II, triglyceride, and total cholesterol from the thoracic duct lymph into plasma was measured in 2 subjects before and 3 subjects after renal transplantation. Lymph triglyceride transport was ~
Anderson, DW +8 more
core +1 more source
Cell Reports, 2017 Lipoprotein cholesterol is delivered to the limiting membrane of late endosomes/lysosomes (LELs) by Niemann-Pick C1 (NPC1). However, the mechanism of cholesterol transport from LELs to the endoplasmic reticulum (ER) is poorly characterized.
Kexin Zhao, Neale D. Ridgway
doaj +1 more source
Peroxisomes in intracellular cholesterol transport: from basic physiology to brain pathology
Exploration of Neuroprotective Therapy, 2021 Peroxisomes are actively involved in the metabolism of various lipids including fatty acids, ether phospholipids, bile acids as well as the processing of reactive oxygen and nitrogen species.
Jian Xiao, Bao-Liang Song, Jie Luo
doaj +1 more source
The secondary structure of apolipoprotein A-I on 9.6-nm reconstituted high-density lipoprotein determined by EPR spectroscopy. [PDF]
, 2013 Apolipoprotein A-I (ApoA-I) is the major protein component of high-density lipoprotein (HDL), and is critical for maintenance of cholesterol homeostasis.
Borja, Mark S +5 more
core +1 more source
The role of the lymphatic system in cholesterol transport [PDF]
, 2015 Reverse cholesterol transport (RCT) is the pathway for removal of peripheral tissue cholesterol and involves transport of cholesterol back to liver for excretion, starting from cellular cholesterol efflux facilitated by lipid-free apolipoprotein A1 ...
Andrew Elvington +2 more
core +3 more sources
eLife, 2017 Cells employ regulated transport mechanisms to ensure that their plasma membranes (PMs) are optimally supplied with cholesterol derived from uptake of low-density lipoproteins (LDL) and synthesis.
Rodney Elwood Infante +1 more
doaj +1 more source