Results 11 to 20 of about 4,882 (132)

Familial cholesteryl ester transfer protein deficiency is associated with triglyceride-rich low density lipoproteins containing cholesteryl esters of probable intracellular origin.

Journal of Lipid Research, 1991
The net transfer of core lipids between lipoproteins is facilitated by cholesteryl ester transfer protein (CETP). We have recently documented CETP deficiency in a family with hyperalphalipoproteinemia, due to a CETP gene splicing defect.
CL Bisgaier, MV Siebenkas, ML Brown, A Inazu, J Koizumi, H Mabuchi, AR Tall   +6 more
doaj   +1 more source

Epitope mapping for the anti-rabbit cholesteryl ester transfer protein monoclonal antibody that selectively inhibits triglyceride transfer

Journal of Lipid Research, 1999
Among the monoclonal antibodies (Mab) against rabbit plasma cholesteryl ester transfer protein (CETP), Mab 14-8F cross-reacted with human CETP and selectively inhibited triglyceride transfer but not cholesteryl ester transfer (Ko, K. W. S., T.
Kazunori Saito, Ki-ichiro Kobori, Hideyuki Hashimoto, Sachiko Ito, Mitsuhisa Manabe, Shinji Yokoyama   +5 more
doaj   +1 more source

Effect of growth hormone replacement therapy on plasma lecithin:cholesterol acyltransferase and lipid transfer protein activities in growth hormone-deficient adults

Journal of Lipid Research, 2000
The effects of growth hormone (GH) replacement on plasma lecithin:cholesterol acyltransferase (LCAT), cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP), factors involved in high density lipoprotein (HDL) metabolism, are ...
John A.M. Beentjes, Arie van Tol, Wim J. Sluiter, Robin P.F. Dullaart   +3 more
doaj   +1 more source

Cholesteryl Ester Transfer Protein (CETP) expression does not affect glucose homeostasis and insulin secretion: studies in human CETP transgenic mice [PDF]

Lipids in Health and Disease, 2016
Oliveira Hcf, Emerielle C Vanzela
exaly   +2 more sources

Biochemical characterization of cholesteryl ester transfer protein inhibitors

Journal of Lipid Research, 2010
Cholesteryl ester transfer protein (CETP) has been identified as a novel target for increasing HDL cholesterol levels. In this report, we describe the biochemical characterization of anacetrapib, a potent inhibitor of CETP.
Mollie Ranalletta, Kathleen K. Bierilo, Ying Chen, Denise Milot, Qing Chen, Elaine Tung, Caroline Houde, Nadine H. Elowe, Margarita Garcia-Calvo, Gene Porter, Suzanne Eveland, Betsy Frantz-Wattley, Mike Kavana, George Addona, Peter Sinclair, Carl Sparrow, Edward A. O'Neill, Ken S. Koblan, Ayesha Sitlani, Brian Hubbard, Timothy S. Fisher   +20 more
doaj   +1 more source

Transfer of cholesteryl ester into high density lipoprotein by cholesteryl ester transfer protein: effect of HDL lipid and apoprotein content.

Journal of Lipid Research, 1989
Recombinant high density lipoprotein (rHDL) particles were prepared by cosonication of purified lipids and human apoproteins and incubated with partly purified cholesteryl ester transfer protein (CETP) and low density lipoprotein (LDL) containing [3H ...
D L Sparks, P H Pritchard
doaj   +1 more source

Characterization of cholesteryl ester transfer protein inhibitor from plasma of baboons (Papio sp.)

Journal of Lipid Research, 1993
Selective breeding has produced families of baboons that accumulate large high density lipoproteins (HDL1) when challenged with a high cholesterol and high fat (HCHF) diet.
RS Kushwaha, SQ Hasan, HC McGill, Jr, GS Getz, RG Dunham, P Kanda   +5 more
doaj   +1 more source

Modification of CETP function by changing its substrate preference: a new paradigm for CETP drug design

Journal of Lipid Research, 2015
We previously determined that hamster cholesteryl ester transfer protein (CETP), unlike human CETP, promotes a novel one-way transfer of TG from VLDL to HDL, causing HDL to gain lipid. We hypothesize that this nonreciprocal lipid transfer activity arises
Richard E. Morton, Lahoucine Izem
doaj   +1 more source

Human liposarcoma cell line, SW872, secretes cholesteryl ester transfer protein in response to cholesterol

Journal of Lipid Research, 1996
Cholesteryl ester transfer protein (CETP) mediates the exchange of phospholipids and neutral lipids between the plasma lipoproteins, and plays an important role in high density lipoprotein (HDL) metabolism.
M A Richardson, D T Berg, P A Johnston, D McClure, B W Grinnell   +4 more
doaj   +1 more source

The role of plasma lipid transfer proteins in lipoprotein metabolism and atherogenesis

Journal of Lipid Research, 2009
The plasma lipid transfer proteins promote the exchange of neutral lipids and phospholipids between the plasma lipoproteins. Cholesteryl ester transfer protein (CETP) facilitates the removal of cholesteryl esters from HDL and thus reduces HDL levels ...
David Masson, Xian-Cheng Jiang, Laurent Lagrost, Alan R. Tall   +3 more
doaj   +1 more source