Results 21 to 30 of about 5,014,718 (261)
Physiological characteristics of allo-cholic acid [PDF]
Journal of Lipid Research, 2003 The physiological characterstics of allo-cholic acid (ACA), a typically fetal bile acid that reappears during liver regeneration and carcinogenesis were investigated. [(14)C] Tauro-ACA (TACA) uptake by Chinese hamster ovary cells expressing rat organic anion transporter polypeptide (Oatp)1 or sodium-taurocholate cotransporter polypeptide (Ntcp) was ...
Mendoza, Maria E. +7 more
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Screening the binding affinity of bile acid derivatives for the glucocorticoid receptor ligand-binding domain [PDF]
Journal of the Serbian Chemical Society, 2023 The necessity of anti-inflammatory drugs such as glucocorticoids has been evident during the COVID-19 pandemic. Glucocorticoids, are the standard therapy for the treatment of moderate and severe COVID-19 patients.
Bjedov Srđan +7 more
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Cholic acid–quinoxaline (2/1) [PDF]
Acta Crystallographica Section E Structure Reports Online, 2008 In the title inclusion compound, 2C(24)H(40)O(5)·C(8)H(6)N(2), the unit cell contains two mol-ecules of cholic acid (3α,7α,12α-trihydr-oxy-5β-cholan-24-oic acid) and one mol-ecule of quinoxaline which implies disorder of the quinoxaline in the space group P2(1).
Maria Gdaniec, Barbara Wicher
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ACS Chemical Neuroscience, 2019 Protein misfolding and its deviant self-assembly to converge into amyloid fibrils is associated with the perturbation of cellular functions and thus with debilitating neurodegenerative diseases including Alzheimer's disease, Parkinson's disease, etc.
Nabeela Majid +7 more
semanticscholar +1 more source
Bioconjugate chemistry, 2019 A major impediment to developing effective antimicrobials against Gram-negative bacteria like Salmonella is the ability of the bacteria to develop resistance against existing antibiotics and the inability of the antimicrobials to clear the intracellular ...
K. Yadav +14 more
semanticscholar +1 more source
Orphanet Journal of Rare Diseases, 2018 BackgroundOral cholic acid (CA) replacement has been shown to be an effective therapy in children with primary bile acid synthesis defects, which are rare and severe genetic liver diseases.
E. Gonzales +10 more
semanticscholar +1 more source
Journal of Pediatric Gastroenterology and Nutrition - JPGN, 2017 Objectives: Patients with bile acid synthesis disorders (BASDs) due to single enzyme defects (SEDs) or Zellweger spectrum disorders (ZSDs) accumulate hepatotoxic atypical bile acids resulting in potentially fatal progressive liver disease.
J. Heubi, K. Bove, K. Setchell
semanticscholar +1 more source
Synthesis of Both Ionic Species of Ammonium Dithiocarbamate Derived Cholic Acid Moieties
Molecules, 2011 The reaction of 3-aminopropylamide of cholic acid with CS2 produced a bile acid derivative of dithiocarbamic acid which further formed an ammonium salt with another molecule of 3-aminopropylamide of cholic acid.
Erkki Kolehmainen, Juha Koivukorpi
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Microbiological Dehydroxylation of Cholic Acid [PDF]
Nature, 1963 THE transformation of steroids by micro-organisms has been extensively applied to the steroid hormones and their derivatives1. More recently this technique has been extended to other compounds2. However, the dehydroxylation reaction of steroids by micro-organisms has not been reported.
Katsumi Kurokawa, Shohei Hayakawa
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Gels, 2022 Clindamycin hydrochloride is a widely used antibiotic for topical use, but its main disadvantage is poor skin penetration. Therefore, new approaches in the development of clindamycin topical formulations are of great importance.
Nebojša Pavlović +6 more
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