Results 91 to 100 of about 15,976 (233)

Bile acid metabolism and sleep: Mechanistic interplay and clinical implications of the gut–liver–brain axis

open access: yesSleep Research, Volume 3, Issue 2, Page 170-179, June 2026.
Abstract The bidirectional interplay between sleep and metabolic homeostasis is fundamental to physiological health. While the roles of glucose and lipid metabolism in sleep regulation have been extensively characterized, bile acids (BAs), which are traditionally viewed as digestive surfactants, are emerging as critical metabolic messengers with ...
Yu Jiang   +4 more
wiley   +1 more source

Dansyl-labeled cholic acid as a tool to build speciation diagrams for the aggregation of bile acids

open access: yes, 2012
Bile acids (BAs) are a family of natural steroids biosynthesized from cholesterol in the liver that tend to form aggregates in solution. A fluorescent derivative of cholic acid, namely 3 alpha-Dns-ChA, was employed as a reporter to establish the ...
Miranda Alonso, Miguel Ángel   +2 more
core   +1 more source

Silicic acid thin-layer chromatography of conjugated and free bile acids

open access: yesJournal of Lipid Research, 1976
The separation of free bile acids, taurine conjugates, and glycine conjugates from one another was achieved by thin-layer chromatography, using a solvent system of isopropanol–glacial acetic acid 93:7 in a solvent system of hexane–methylethylketone ...
M N Chavez, C L Krone
doaj   +1 more source

Advances in cholesterol and lipoproteins detection for healthcare: A review

open access: yesVIEW, Volume 7, Issue 3, June 2026.
Cholesterol is one of the main biomarkers related to the development of cardiovascular diseases. Its detection still relies on traditional methods of analysis, such as gas and liquid chromatographies. Detection of free cholesterol in saliva with redox or enzymatic sensors or detection of lipoproteins in blood with aptamer sensors are currently the most
Jacopo Giaretta   +7 more
wiley   +1 more source

Effects of cholic acid on the metabolism of endogenous plasma triglyceride and on biliary lipid composition in hyperlipoproteinemia.

open access: yesJournal of Lipid Research, 1980
Plasma lipids, endogenous triglyceride kinetics, and biliary lipid composition were determined in 13 patients with primary hyperlipoproteinemia (HLP) before and during treatment with cholic acid (15 mg/kg body weight/day for 3 months).
B Angelin, B Leijd
doaj   +1 more source

A Single Amino Acid Substitution in CspA Increases Germination Sensitivity and Broadens Bile Salt Germinant Specificity in Clostridioides difficile Spores

open access: yesEnvironmental Microbiology, Volume 28, Issue 6, June 2026.
In reservoir‐associated RT033 strains, we observe a natural rewiring of spore germination that lowers the activation threshold and broadens bile‐salt specificity, enabling germination at low germinant levels and in response to typically inhibitory bile‐salts common in animal hosts.
Isabel Roseiro   +7 more
wiley   +1 more source

Cholic acid is accumulated spontaneously, driven by membrane Delta pH, in many lactobacilli

open access: yes, 2000
Many lactobacilli from various origins were found to apparently lack cholic acid extrusion activity. Cholic acid was accumulated spontaneously, driven by the transmembrane proton gradient.
Mierau, [No Value]   +7 more
core   +1 more source

Comparative effects of cholic, chenodeoxycholic, and ursodeoxycholic acids on micellar solubilization and intestinal absorption of cholesterol

open access: yesJournal of Lipid Research, 1981
Cholesterol absorption was studied in mice receiving cholic, chenodeoxycholic, or ursodeoxycholic acids (0.2% of the diet) for 2 months. Cholesterol absorption was greater with cholic acid (79%) than with chenodeoxycholic acid feeding (60%) and the ...
M O Reynier   +6 more
doaj   +1 more source

Novel Symptom Subgroups in Patients With Irritable Bowel Syndrome Are Associated With Healthcare Utilisation in Secondary and Tertiary Care

open access: yesAlimentary Pharmacology &Therapeutics, Volume 63, Issue 11, Page 1474-1486, June 2026.
In patients with IBS in secondary and tertiary care, latent class analysis model identified groups of individuals with more severe symptoms and greater impairments in quality of life at baseline and significantly higher rates of healthcare utilisation during longitudinal follow‐up. ABSTRACT Background & Aims Current classification systems for irritable
Vivek C. Goodoory   +12 more
wiley   +1 more source

Formation of urso- and ursodeoxy-cholic acids from primary bile acids by Clostridium absonum

open access: yesJournal of Lipid Research, 1981
Eight strains of Clostridium absonum were shown to form ursocholic acid (UC) from cholic acid (C) and ursodeoxycholic acid (UDC) from chenodeoxycholic acid (CDC) but did not transform deoxycholic acid (DC) in whole cell cultures. The structures of UC and
I A Macdonald   +2 more
doaj   +1 more source

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