Results 1 to 10 of about 236,274 (244)

Comparative genomics and mutagenesis analyses of choline metabolism in the marine Roseobacter clade [PDF]

, 2015
Choline is ubiquitous in marine eukaryotes and appears to be widely distributed in surface marine waters; however, its metabolism by marine bacteria is poorly understood.
Andresen P.A., Gauthier M.J., Ghoul M., Ikawa M., Kiene R.P., Nau‐Wagner G., Prado S.   +6 more
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Biochemical characterization of the initial steps of the Kennedy pathway in Trypanosoma brucei:the ethanolamine and choline kinases [PDF]

, 2008
Note related output below contains correction of this paper.Ethanolamine and choline are major components of the trypanosome membrane phospholipids, in the form of GPEtn (glycero-phosphoethanolamine) and GPCho (glycerophosphocholine).
Ayoama, Baba, Bürgemaister, Chang, Choubey, Clary, Cuadrado, Dowhan, Federica Gibellini, Ferguson, Gee, Imhof, Kennedy, Kim, Kim, Malito, Menon, Menon, Nagamune, Patnaik, Peisach, Rifkin, Scheef, Smith, Terry K. Smith, Urbina, Wharfe, William N. Hunter, Yuan   +28 more
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Choline supplements: An update

Frontiers in Endocrinology, 2023
In this comprehensive review, we examine the main preclinical and clinical investigations assessing the effects of different forms of choline supplementation currently available, including choline alfoscerate (C8H20NO6P), also known as alpha-glycerophosphocholine (α-GPC, or GPC), choline bitartrate, lecithin, and citicoline, which are cholinergic ...
Urna Kansakar, Valentina Trimarco, Pasquale Mone, Pasquale Mone, Fahimeh Varzideh, Angela Lombardi, Gaetano Santulli, Gaetano Santulli, Gaetano Santulli   +8 more
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Dysregulated Choline, Methionine, and Aromatic Amino Acid Metabolism in Patients with Wilson Disease: Exploratory Metabolomic Profiling and Implications for Hepatic and Neurologic Phenotypes. [PDF]

, 2019
Wilson disease (WD) is a genetic copper overload condition characterized by hepatic and neuropsychiatric symptoms with a not well-understood pathogenesis.
Czlonkowska, Anna, Kim, Kyoungmi, Litwin, Tomasz, Mazi, Tagreed A, Medici, Valentina, Sarode, Gaurav V, Shibata, Noreene M   +6 more
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Does litomosoides sigmodontis synthesize dimethylethanolamine from choline? [PDF]

, 2008
Juvenile female Litomosoides sigmodontis secrete a protein (Juv-p120) highly modified with dimethylethanolamine (DMAE). In an attempt to establish the source of this decoration worms were pulsed with [3H]-choline and [3H]-ethanolamine and the radio ...
Allen, J E, Allen, Judith, Babayan, S A, Harnett, W, Houston, K M   +4 more
core   +2 more sources

Functional genomics with a comprehensive library of transposon mutants for the sulfate-reducing bacterium Desulfovibrio alaskensis G20. [PDF]

, 2014
UnlabelledThe genomes of sulfate-reducing bacteria remain poorly characterized, largely due to a paucity of experimental data and genetic tools. To meet this challenge, we generated an archived library of 15,477 mapped transposon insertion mutants in the
Arkin, Adam P, Davis, Ronald W, Deutschbauer, Adam, Esquivel, Zuelma, Hazen, Terry C, Kazakov, Alexey E, Kuehl, Jennifer V, Kuehn, Raquel, Nguyen, Michelle, Price, Morgan N, Ray, Jayashree, Wetmore, Kelly M   +11 more
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Potential of choline chloride - based natural deep eutectic solvents (NaDES) in the extraction of microalgal metabolites [PDF]

, 2017
In a typical chemical process, the solvents are widely used for the dissolution of the reagents, to favor the kinetics and the thermodynamics of a chemical reaction, for the extraction of products, for the separation of mixtures.
Bravi, Marco, Cicci, Agnese, Sed, Giorgia   +2 more
core   +1 more source

Generation of Choline for Acetylcholine Synthesis by Phospholipase D Isoforms [PDF]

, 2001
DEDICATION: This article is dedicated to the memory of Sue Kim Hanson, a graduate student in the department of Pathology and Laboratory Medicine at Boston University School of Medicine, who perished in the terrorist attacks of September 11, 2001 ...
Blusztajn, Jan Krzysztof, Frohman, Michael A, Zhao, Di   +2 more
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Choline Redistribution during Adaptation to Choline Deprivation [PDF]

Journal of Biological Chemistry, 2007
Choline is an important nutrient for mammals. Choline can also be generated by the catabolism of phosphatidylcholine synthesized in the liver by the methylation of phosphatidylethanolamine by phosphatidylethanolamine N-methyltransferase (PEMT). Complete choline deprivation is achieved by feeding Pemt(-)(/)(-) mice a choline-deficient diet and is lethal
Dennis E. Vance, Luis B. Agellon, Zhaoyu Li   +2 more
openaire   +3 more sources

Anticancer activity of rutin and its combination with ionic liquids on renal cells [PDF]

, 2020
The renal cell carcinoma (RCC) is the most common type of kidney cancer. Identifying novel and more effective therapies, while minimizing toxicity, continues to be fundamental in curtailing RCC.
Araújo, Maria Eduarda Machado, Baby, André Rolim, Caparica, Rita, Costa, João Guilherme, Fonte, Pedro, Júlio, Ana, Santos de Almeida, Tânia   +6 more
core   +1 more source