Results 1 to 10 of about 273,862 (336)

Choline supplements: An update

Frontiers in Endocrinology, 2023
In this comprehensive review, we examine the main preclinical and clinical investigations assessing the effects of different forms of choline supplementation currently available, including choline alfoscerate (C8H20NO6P), also known as alpha ...
Urna Kansakar, Valentina Trimarco, Pasquale Mone, Pasquale Mone, Fahimeh Varzideh, Angela Lombardi, Gaetano Santulli, Gaetano Santulli, Gaetano Santulli   +8 more
doaj   +4 more sources

Alcohol Exposure May Increase Prenatal Choline Needs Through Redirection of Choline into Lipid Synthesis Rather than Methyl Donation [PDF]

Metabolites
Background: Prenatal alcohol exposure (PAE) can reduce fetal growth and cause neurodevelopmental disability. Prenatal choline supplements attenuate PAE-induced behavioral and growth deficits; however, the underlying mechanisms are unknown. Alcohol alters
Hannah G. Petry, Nipun Saini, Susan M. Smith, Sandra M. Mooney   +3 more
doaj   +2 more sources

Functional Expression of Choline Transporters in Human Neural Stem Cells and Its Link to Cell Proliferation, Cell Viability, and Neurite Outgrowth

Cells, 2021
Choline and choline metabolites are essential for all cellular functions. They have also been reported to be crucial for neural development. In this work, we studied the functional characteristics of the choline uptake system in human neural stem cells ...
Yosuke Fujita, Tomoki Nagakura, Hiroyuki Uchino, Masato Inazu, Tsuyoshi Yamanaka   +4 more
doaj   +1 more source

Herbal choline as an alternative to choline chloride in the diet of nursery piglets

Pesquisa Agropecuária Brasileira, 2023
The objective of this work was to evaluate the replacement of choline chloride supplementation by herbal choline in the diet of nursery piglets. The experimental design was randomized complete blocks (initial weight and sex) with 80 piglets, in five ...
Letícia Lopes de Godoi, Laya Kannan Silva Alves, Ana Luísa Neves Alvarenga Dias, Hebert Silveira, Cesar Augusto Pospissil Garbossa   +4 more
doaj   +1 more source

Food Sources Contributing to Intake of Choline and Individual Choline Forms in a Norwegian Cohort of Patients With Stable Angina Pectoris

Frontiers in Nutrition, 2021
Background: Choline is an essential nutrient involved in a wide range of physiological functions. It occurs in water- and lipid-soluble forms in the body and diet.
Anthea Van Parys, Therese Karlsson, Kathrine J. Vinknes, Thomas Olsen, Jannike Øyen, Jutta Dierkes, Jutta Dierkes, Jutta Dierkes, Ottar Nygård, Ottar Nygård, Ottar Nygård, Vegard Lysne, Vegard Lysne, Vegard Lysne   +13 more
doaj   +1 more source

Physiological and lipidomic response of exogenous choline chloride alleviating salt stress injury in Kentucky bluegrass (Poa pratensis)

Frontiers in Plant Science, 2023
IntroductionCholine participates in plant stress tolerance through glycine betaine (GB) and phospholipid metabolism. As a salt-sensitive turfgrass species, Kentucky bluegrass (Poa pratensis) is the main turfgrass species in cool-season areas.MethodsTo ...
Zhi-Fang Zuo, Yan Li, Xin-Feng Mi, Yong-Long Li, Chen-Yuan Zhai, Guo-Feng Yang, Zeng-Yu Wang, Kun Zhang   +7 more
doaj   +1 more source

Mapping of exogenous choline uptake and metabolism in rat glioblastoma using deuterium metabolic imaging (DMI)

Frontiers in Cellular Neuroscience, 2023
IntroductionThere is a lack of robust metabolic imaging techniques that can be routinely applied to characterize lesions in patients with brain tumors. Here we explore in an animal model of glioblastoma the feasibility to detect uptake and metabolism of ...
Kevan L. Ip, Monique A. Thomas, Kevin L. Behar, Robin A. de Graaf, Robin A. de Graaf, Henk M. De Feyter   +5 more
doaj   +1 more source

Effects of herbal choline as a replacement for choline chloride on myopathy, locomotor system, and hepatic health of broilers

Revista Brasileira de Zootecnia, 2023
The objective of this study was to evaluate the effects of replacing choline chloride with a plant source of choline on the locomotor system, liver health, and development of breast myopathies in broilers aged 1-42 days of age. We allocated 1,120 one-day-
Allan Gabriel Ferreira Dias, Ana Paula Iglesias Santin, Júlio César Lopes Brasileiro, Carla Daniela Suguimoto Leite, José Henrique Stringhini, Alison Batista Vieira Silva Gouveia, Júlia Marixara Sousa da Silva, Marcos Barcellos Café   +7 more
doaj   +1 more source

Serial plasma choline measurements after cardiac arrest in patients undergoing mild therapeutic hypothermia: a prospective observational pilot trial. [PDF]

PLoS ONE, 2013
OBJECTIVE: Choline is related to phospholipid metabolism and is a marker for global ischaemia with a small reference range in healthy volunteers. The aim of our study was to characterize the early kinetics of plasma free choline in patients after cardiac
Christian Storm, Oliver Danne, Per Magne Ueland, Christoph Leithner, Dietrich Hasper, Tim Schroeder   +5 more
doaj   +1 more source

Protective Effects of Choline against Inflammatory Cytokines and Characterization of Transport in Motor Neuron-like Cell Lines (NSC-34)

Pharmaceutics, 2022
Choline, a component of the neurotransmitter acetylcholine, is essential for nervous system functions, brain development, and gene expression. In our study, we investigated the protective effect and transport characteristics of choline in amyotrophic ...
Sana Latif, Young-Sook Kang
doaj   +1 more source