Results 11 to 20 of about 169,479 (311)
Physiological Reports, 2022 Vitronectin (VTN) is a glycoprotein enriched in the blood and activates integrin receptors. VTN blood levels increase only in female mice 24 h after an ischemic stroke and exacerbate brain injury through IL‐6‐driven inflammation, but the VTN induction ...
Matthew P. Keasey +3 more
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Frontiers in Pharmacology, 2018 Nicotinic acetylcholine receptors (nAChRs) expressed on the cell plasma membrane are ligand-gated ion channels mediating fast synaptic transmission, regulating neurotransmitter and cytokine release and supporting the viability of many cell types.
Kateryna Uspenska +6 more
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Systematic review of the pharmacological properties of oligodendrocyte lineage
Frontiers in Cellular Neuroscience, 2016 OOligodendrogenesis and oligodendrocyte precursor maturation are essential processes during the course of central nervous system development, and lead to the myelination of axons.
Carla eMarinelli +4 more
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Propranolol Relieves L-Dopa-Induced Dyskinesia in Parkinsonian Mice
Brain Sciences, 2020 Background: Parkinsonism is caused by dopamine (DA) insufficiency and results in a hypokinetic movement disorder. Treatment with L-Dopa can restore DA availability and improve motor function, but patients can develop L-Dopa-induced dyskinesia (LID), a ...
Ziqing Shi +5 more
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An essential role of acetylcholine-glutamate synergy at habenular synapses in nicotine dependence
eLife, 2015 A great deal of interest has been focused recently on the habenula and its critical role in aversion, negative-reward and drug dependence. Using a conditional mouse model of the ACh-synthesizing enzyme choline acetyltransferase (Chat), we report that ...
Silke Frahm +5 more
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Cell type-specific long-range connections of basal forebrain circuit
eLife, 2016 The basal forebrain (BF) plays key roles in multiple brain functions, including sleep-wake regulation, attention, and learning/memory, but the long-range connections mediating these functions remain poorly characterized.
Johnny Phong Do +10 more
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Neural regulation of ILC2s in allergic airway inflammation
Frontiers in Allergy, 2023 The sympathetic nervous system (SNS) and parasympathetic nervous system (PNS) regulate the effector functions of group 2 innate lymphoid cells (ILC2s) through β2 adrenergic receptor (ADRB2) and nicotinic/muscarinic cholinergic receptor signaling ...
Christopher M. Thomas +3 more
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Preface: Cholinergic Mechanisms [PDF]
Journal of Neurochemistry, 2017 This special issue is a companion to the meeting 'XVth International Symposium on Cholinergic Mechanisms', and is edited by Israel Silman, Marco Prado and Pascale Marchot. In the review articles, renowned researchers in the field capture key mechanisms of cholinergic neurotransmission, from genomic amplification of cholinesterase genes, splicing and ...
Prado, Marco +3 more
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Pro-cognitive drug effects modulate functional brain network organization
Frontiers in Behavioral Neuroscience, 2012 Previous studies document that cholinergic and noradrenergic drugs improve attention, memory and cognitive control in healthy subjects and patients with neuropsychiatric disorders.
Carsten eGiessing, Christiane M Thiel
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The Mesoscopic Connectome of the Cholinergic Pontomesencephalic Tegmentum
Frontiers in Neuroanatomy, 2022 The pontomesencephalic tegmentum, comprising the pedunculopontine nucleus and laterodorsal tegmental nucleus, is involved in various functions via complex connections; however, the organizational structure of these circuits in the whole brain is not ...
Peilin Zhao +9 more
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