A Cholinergic Synaptically Triggered Event Participates in the Generation of Persistent Activity Necessary for Eye Fixation [PDF]
, 2004 An exciting topic regarding integrative properties of the nervous system is how transient motor commands or brief sensory stimuli are able to evoke persistent neuronal changes, mainly as a sustained, tonic action potential firing.
Alvarado, JC +5 more
core +4 more sources
Corticofugal and Brainstem Functions Associated With Medial Olivocochlear Cholinergic Transmission
Frontiers in Neuroscience, 2022 Cholinergic transmission is essential for survival and reproduction, as it is involved in several physiological responses. In the auditory system, both ascending and descending auditory pathways are modulated by cholinergic transmission, affecting the ...
Felipe Munoz +9 more
doaj +1 more source
The PPN and motor control: Preclinical studies to deep brain stimulation for Parkinson’s disease
Frontiers in Neural Circuits, 2023 The pedunculopontine nucleus (PPN) is the major part of the mesencephalic locomotor region, involved in the control of gait and locomotion. The PPN contains glutamatergic, cholinergic, and GABAergic neurons that all make local connections, but also have ...
Caixia Lin +4 more
doaj +1 more source
Cholinergic cells in the nucleus basalis of mice express the N-methyl-D-aspartate-receptor subunit NR2C and its replacement by the NR2B subunit enhances frontal and amygdaloid acetylcholine levels [PDF]
, 2006 It is known that glutamatergic and cholinergic systems interact functionally at the level of the cholinergic basal forebrain. The N-methyl-D-aspartate receptor (NMDA-R) is a multiprotein complex composed of NR1, NR2 and/or NR3 subunits.
Broide R.S. +11 more
core +7 more sources
An optimized acetylcholine sensor for monitoring in vivo cholinergic activity
Nature Methods, 2020 The ability to directly measure acetylcholine (ACh) release is an essential step toward understanding its physiological function. Here we optimized the GRABACh (GPCR-activation-based ACh) sensor to achieve substantially improved sensitivity in ACh ...
Miao Jing +23 more
semanticscholar +1 more source
The Neat Dance of COVID-19: NEAT1, DANCR, and Co-Modulated Cholinergic RNAs Link to Inflammation
Frontiers in Immunology, 2020 The COVID-19 pandemic exerts inflammation-related parasympathetic complications and post-infection manifestations with major inter-individual variability.
Chanan Meydan +4 more
doaj +1 more source
Cyclosporine in Cholinergic Itch
Indian Dermatology Online Journal, 2022 Cholinergic itch is part of symptom complex that also includes cholinergic erythema and cholinergic urticaria. It mostly occurs during the winters among young adults. It is characterized by onset of severe itching or burning sensation all over body, mostly, on exposure to sunlight, warm atmosphere and in some cases after hot ...
Sumit Sehgal +5 more
openaire +3 more sources
Frontiers in Pharmacology, 2018 Nicotinic acetylcholine receptors (nAChRs) expressed on the cell plasma membrane are ligand-gated ion channels mediating fast synaptic transmission, regulating neurotransmitter and cytokine release and supporting the viability of many cell types.
Kateryna Uspenska +6 more
doaj +1 more source
Accidental organophosphate poisoning: A case series of 2 pediatric coumaphos exposures
Journal of the American College of Emergency Physicians Open, 2022 Introduction Pediatric organophosphate insecticide poisonings are rare in the United States, and life‐threatening toxicity is rarely seen. We report 2 accidental ingestions of the organophosphate insecticide coumaphos that resulted in life‐threatening ...
Justin A. Seltzer +12 more
doaj +1 more source
Frontiers in Neuroscience, 2021 Food is the primary human source of choline, an essential precursor to the neurotransmitter acetylcholine, which has a central role in signaling pathways that govern sensorimotor functions.
Audrey Olson +7 more
doaj +1 more source