Results 151 to 160 of about 27,370 (335)

Association between CMR‐derived hepatic T1‐time, tricuspid regurgitation and survival

open access: yesEuropean Journal of Clinical Investigation, EarlyView.
We investigated the association between tricuspid regurgitation (TR) severity and hepatic T1‐time in 1029 patients undergoing cardiac MRI and echocardiography. Hepatic T1‐time increased progressively with TR severity and remained independently associated after adjusting for NT‐proBNP and right ventricular function. Both TR and hepatic T1‐time predicted
Katharina Mascherbauer   +19 more
wiley   +1 more source

The human photosensitive epilepsy model for clinical proof‐of‐principle trials of novel antiseizure medications: 2. Analysis of drug trials and predictive value of the model

open access: yesEpilepsia, EarlyView.
Abstract Clinical development of novel antiseizure medications (ASMs) would benefit from an early proof of principle (POP) model. The photosensitivity model, which uses the photoparoxysmal electroencephalographic response (PPR) as a surrogate of seizures, is currently the only human model that allows POP trials of investigational compounds after a ...
Wolfgang Löscher   +1 more
wiley   +1 more source

Assay for heavy metals using an inhibitive assay based on the acetylcholinesterase from Channa striatus [PDF]

open access: yes, 2017
Acetylcholinesterase (AChE) is usually used as an inhibitive assay for insecticides. A lesser known property of AChE is its inhibition by heavy metals.
Abd. Shukor, Mohd. Yunus   +6 more
core  

Assessing the Content of Goals of Care Documentation for Hospitalized Patients With Alzheimer's Disease and Related Dementias

open access: yesJournal of the American Geriatrics Society, EarlyView.
Documented Patient Values and Preferences and Attendance at Goals of Care Conversations. AD/ADRD—Alzheimer's disease and related dementias. ABSTRACT Background Goals of care (GOC) conversations are an evidence‐based practice that help clarify and align patient values and preferences for medical care with treatment options.
Gina Piscitello   +5 more
wiley   +1 more source

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