Results 181 to 190 of about 170,603 (392)

Synaptic Dysfunction in the Anterior Cingulate Cortex Underlies Pain‐Anxiety Comorbidity in a Mandibular Asymmetry Mouse Model

open access: yesAdvanced Science, EarlyView.
This study establishes a mandibular asymmetry (MA) mouse model that recapitulates chronic orofacial pain and anxiety comorbidity. Anterior cingulate cortex (ACC) hyperactivation and synaptic dysfunction are identified as central neural mechanisms underlying these pathologies, with chemogenetic inhibition of ACC CaMKII+ neurons effectively reversing ...
Zhaoyichun Zhang   +19 more
wiley   +1 more source

Inhibition of SAT1 alleviates chondrocyte inflammation and ferroptosis by repressing ALOX15 expression and activating the Nrf2 pathway

open access: yesBone & Joint Research
Aims: Osteoarthritis (OA) is the most common chronic pathema of human joints. The pathogenesis is complex, involving physiological and mechanical factors. In previous studies, we found that ferroptosis is intimately related to OA, while the role of Sat1
Jingting Xu   +9 more
doaj   +1 more source

Isolation and characterization of proteoglycans from chick limb bud chondrocytes grown in vitro.

open access: hybrid, 1976
Vincent Hascall   +3 more
openalex   +1 more source

Magnetized Cell‐Scaffold Constructs for Bone Tissue Engineering: Advances in Fabrication and Magnetic Stimulation

open access: yesAdvanced Science, EarlyView.
This review highlights the synthesis and applications of magnetized cells (MCs) and magnetized scaffolds (MSs) in advancing bone tissue engineering strategies. It further demonstrates how magnetic particles (MPs) improve scaffold properties and how external magnetic fields enhance mesenchymal stem cell adhesion, proliferation, and osteogenic ...
Elio Cinar SanSegundo   +3 more
wiley   +1 more source

Competitive Binding of Somatomedin to the Insulin Receptors of Adipocytes, Chondrocytes, and Liver Membranes

open access: green, 1972
Raymond L. Hintz   +3 more
openalex   +1 more source

Biological Effect of Estradiol on phosphatase activities in rabbit cultured chondrocytes [PDF]

open access: bronze, 1981
Antonio Carrascosa   +3 more
openalex   +1 more source

The Sirt1‐Piezo1 Axis Promotes Bone Formation and Repair in Mice

open access: yesAdvanced Science, EarlyView.
Piezo1 upregulates in cartilage callus during bone repair, where its deletion impairs ossification and healing in mice, while activation enhances these processes. Sirt1 positively regulates Piezo1 expression and activity to promote osteogenesis and bone repair in mice.
Donghao Gan   +16 more
wiley   +1 more source

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