Results 51 to 60 of about 170,603 (392)
In osteoarthritis (OA), the articular cartilage covering the articular surface of the bone wears out, exposing the subchondral bone, and the synovial membrane surrounding the joint becomes inflamed, causing pain and deformity.
Hun Hwan Kim+11 more
doaj +1 more source
Osteochondrosis lesions of the lateral trochlear ridge of the distal femur in four ponies [PDF]
Lesions of the lateral trochlear ridge (LTR) of the distal femur were investigated in four pony or pony cross horses. The animals were all geldings and were six to 15 months of age.
Henson, F.M.D.+3 more
core +1 more source
Long non-coding RNAs (lncRNAs) play a part in a wide variety of diseases, including osteoarthritis (OA). This study was designed to investigate the biological role of lncRNA LINC00265 in OA and its underlying mechanisms.
Hanlin Zou, Chunde Lu, Jianjun Qiu
doaj +1 more source
Optimization of Sturgeon Cartilage Products and Its Regulation on Human Chondrocyte Inflammation
The purpose of this paper was to prepare a sturgeon cartilage product from sturgeon cartilage and explore its effect on inflammation of human chondrocytes.
Hengge LIU+6 more
doaj +1 more source
Anatomy, morphology and evolution of the patella in squamate lizards and tuatara (Sphenodon punctatus) [PDF]
The patella (kneecap) is the largest and best-known of the sesamoid bones, postulated to confer biomechanical advantages including increasing joint leverage and reinforcing the tendon against compression.
Benjamin M+18 more
core +2 more sources
Role of galectin-3 in bone cell differentiation, bone pathophysiology and vascular osteogenesis [PDF]
Galectin-3 is expressed in various tissues, including the bone, where it is considered a marker of chondrogenic and osteogenic cell lineages. Galectin-3 protein was found to be increased in the differentiated chondrocytes of the metaphyseal plate ...
Fantauzzi, Claudia Blasetti+3 more
core +2 more sources
Sox9 is an intrinsic transcription factor related to the determination and maintenance of chondrogenic lineage of bone marrow mesenchymal stem cells (BMSCs).
Ruikai Ba+6 more
doaj +1 more source
The Elusive Origin of Atherosclerotic Plaque Calcification
It has been known for decades or even centuries that arteries calcify as they age. Vascular calcification probably affects all adults, since virtually all have atherosclerotic plaques: an accumulation of lipids, inflammatory cells, necrotic debris, and ...
Emmanuelle Canet-Soulas+4 more
doaj +1 more source
Octacalcium phosphate crystals directly stimulate expression of inducible nitric oxide synthase through p38 and JNK mitogen-activated protein kinases in articular chondrocytes [PDF]
Basic calcium phosphate (BCP) crystals, including hydroxyapatite, octacalcium phosphate (OCP) and carbonate-apatite, have been associated with severe osteoarthritis and several degenerative arthropathies.
Ea, Hang-Korng+3 more
core +6 more sources
Mechanisms of chondrocyte apoptosis
This study addresses the occurrence and significance of chondrocyte apoptosis in the pathogenesis of cartilage destruction. Chondrocyte apoptosis can be induced in vitro by nitric oxide donors, but not by pro-inflammatory cytokines, such as IL-1 or TNF.
Klaus Kühn+2 more
openaire +3 more sources