Results 181 to 190 of about 731,089 (287)

BMSC-derived exosomes from congenital polydactyly tissue alleviate osteoarthritis by promoting chondrocyte proliferation. [PDF]

Cell Death Discov, 2020
Zhou X, Liang H, Hu X, An J, Ding S, Yu S, Liu C, Li F, Xu Y.   +8 more
europepmc   +1 more source

Natural Polysaccharides for Rheumatoid Arthritis Therapy: Mechanism, Drug Delivery and Clinical Application

Phytotherapy Research, EarlyView.
Schematic overview of the experimental models, therapeutic mechanisms, drug delivery systems, and clinical potential of natural polysaccharides in rheumatoid arthritis. ABSTRACT Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized primarily by chronic synovitis.
Luxin Li, Junnan Li, Guangzhi Li, Lili Huang, Tiantian Wen, Yanying Li, Yan Sun, Zhenqiang Liu, Qingshan Chen, Lili Zhang, Tiangang Lu, Ruiyan Wu, Haixue Kuang, Xiaochi Ma, Yan Liu   +14 more
wiley   +1 more source

Hepatocyte Growth Factor-Mediated Chondrocyte Proliferation Induced by Adipose-Derived MSCs from Osteoarthritis Patients and Its Synergistic Enhancement by Hyaluronic Acid. [PDF]

Int J Mol Sci
Won SJ, Lee HJ, Kim DY, Noh H, Lee SY, Yoo JA, Jeon YS, Shin H, Ryu DJ.   +8 more
europepmc   +1 more source

Advances in research on layered double hydroxides for biomedical applications

Smart Molecules, EarlyView.
Layered double hydroxides (LDHs) are pH‐responsive nanomaterials with broad biomedical applications. This review summarizes LDH synthesis methods and compares their advantages. It highlights LDHs' progress in cancer therapy, including chemo‐photothermal, chemo‐immunotherapy, and photodynamic‐immunotherapy combinations and their potential in bone repair.
Xinhui Yang, Zhiping Zhang, Zhao Wang, Hao Zhang, Yen Leng Pak, Yingying Jing, Yurong Guo, Fang Li, Xiao Wang, Quanxiang Han, Lei Yu, Xuejiao Li, Xing Gao, Jibin Song   +13 more
wiley   +1 more source

Macrophages-derived small extracellular vesicles regulate chondrocyte proliferation and affect osteoarthritis progression via upregulating Osteopontin expression. [PDF]

J Cell Commun Signal
Tu M, Tu M, Liu AM, Huang W, Wang D, Chen HQ, Hu XY.   +6 more
europepmc   +1 more source

Altered IHH signaling contributes to reduced chondrocyte proliferation in the growth plate of MPS VII mice. [PDF]

Mol Genet Metab Rep, 2020
Jiang Z, Derrick-Roberts ALK, Byers S.
europepmc   +1 more source

Recent Advances in Oriented Hydrogels: From Fundamental Mechanisms to Future Challenges

SusMat, EarlyView.
Traditional hydrogels suffer from weak mechanical properties and limited functionality due to their random polymer networks. This review comprehensively summarizes the reinforcement mechanisms of oriented structure for hydrogels, the design/fabrication strategies, and the latest application progress of high‐strength oriented hydrogels.
Chang Xu, Xijing Zhuang
wiley   +1 more source

MicroRNA-197 regulates chondrocyte proliferation, migration, and inflammation in pathogenesis of osteoarthritis by targeting EIF4G2. [PDF]

Biosci Rep, 2020
Gao S, Liu L, Zhu S, Wang D, Wu Q, Ning G, Feng S.   +6 more
europepmc   +1 more source

Antxr1, Which is a Target of Runx2, Regulates Chondrocyte Proliferation and Apoptosis [PDF]

Antxr1/Tem8 is highly expressed in tumor endothelial cells and is a receptor for anthrax toxin. Mutation of Antxr1 causes GAPO syndrome, which is characterized by growth retardation, alopecia, pseudo-anodontia, and optic atrophy.
Yamana, Kei, Hojo, Hironori, Komori, Toshihisa, Komori, Hisato, Jiang, Qing, Croix, Brad St., Qin, Xin, Yoshida, Carolina Andrea, Kawata-Matsuura, Viviane K. S., Ohba, Shinsuke   +9 more
core  

Sustainable and Programmable Hydrogels for Bone Regeneration: A Perspective on Green Synthesis and Precision Fabrication

SusMat, EarlyView.
The clinical translation of natural hydrogels is often hindered by a fundamental conflict. Green synthesis prioritizes biosafety through mild and non‐toxic conditions, whereas precision manufacturing demands mechanical robustness and structural fidelity.
Jiaxin Wu, Xu Wang, Hanfei Li, Xibo Pei, Hao Feng, Jian Wang   +5 more
wiley   +1 more source