Progress in bone tissue engineering biomaterials: Development, challenges, and prospects
Scheme 1 Application of biomaterials in immunomodulation during bone tissue engineering. Abstract Bone defect repair remains a major clinical challenge in orthopedics. Over 2 million cases caused by trauma, tumors, and other factors occur annually, with large‐scale defects posing a particular bottleneck due to limited self‐healing capacity.
Yuanbin Zhang +7 more
wiley +1 more source
Let-7a-5p derived from parathyroid hormone (1-34)-preconditioned BMSCs exosomes delays the progression of osteoarthritis by promoting chondrocyte proliferation and migration. [PDF]
Shao L +7 more
europepmc +1 more source
Effects of Leptin on Differentiation and Proliferation of Chondrocytes
Zhang, Shai +11 more
openaire +2 more sources
ABSTRACT Background Cell therapy, particularly those utilizing mesenchymal stem/stromal cells (MSCs), is gaining traction as a therapeutic option for regenerative treatment in patients with limited therapeutic options. Although the safety of MSC‐based interventions is well established, uncertainties remain regarding how genetic abnormalities and ...
Marzena Zychowicz +12 more
wiley +1 more source
MiR-322-5p is involved in regulating chondrocyte proliferation and differentiation in offspring's growth plate of maternal gestational diabetes. [PDF]
Qian F +7 more
europepmc +1 more source
Hsa_circularRNA_0079201 suppresses chondrocyte proliferation and endochondral ossification by regulating the microRNA‑140‑3p/SMAD2 signaling pathway in idiopathic short stature. [PDF]
Liu X, Yan C, Deng X, Jia J.
europepmc +1 more source
Abstract A healthy tear film is vital for ocular surface integrity and relies on the coordinated function of the lacrimal glands, meibomian glands and conjunctival goblet cells. Dysfunction in any of these elements can lead to dry eye disease (DED). This systematic review and meta‐analysis evaluated the efficacy of low‐level light therapy (LLLT) as a ...
Sjur Reppe +6 more
wiley +1 more source
HOXB6 down-regulation induced by retinoic acid pathway repression leads to chondrocyte proliferation inhibition and apoptosis in microtia. [PDF]
Yang R +9 more
europepmc +1 more source
Dermal chondrosarcoma in a cat with prolonged survival after limb amputation
A 5‐year‐old male entire domestic shorthair cat presented with a firm dermal mass on the dorsal left metatarsal region. Diagnostic investigations included haematology, biochemistry, urinalysis, biopsy, histopathology and computed tomography staging. Histopathology of the tissue biopsy, including immunohistochemistry, confirmed a dermal chondrosarcoma ...
A Ivanovs +5 more
wiley +1 more source
Withdrawal: Nuclear factor-κB p65 facilitates longitudinal bone growth by inducing growth plate chondrocyte proliferation and differentiation and by preventing apoptosis. [PDF]
Wu S, Flint JK, Rezvani G, De Luca F.
europepmc +1 more source

