Results 201 to 210 of about 48,883 (320)

Scalable, High‐Density Expansion of Human Mesenchymal Stem Cells on Microcarriers Using the Bach Impeller in Stirred‐Tank Reactors

Biotechnology and Bioengineering, EarlyView.
ABSTRACT This paper describes the results of process developmental experiments to achieve higher cell densities in the manufacturing of hMSCs using the novel Bach impeller in a stirred‐tank bioreactor. Engineering experiments have previously shown that the Bach impeller represents an efficient mixing device that suspends particles in fluids at low ...
Tom A. Wyrobnik, Laia Miranda, Alan Lam, Steve Oh, Andrea Ducci, Martina Micheletti   +5 more
wiley   +1 more source

MicroRNA-197 regulates chondrocyte proliferation, migration, and inflammation in pathogenesis of osteoarthritis by targeting EIF4G2. [PDF]

Biosci Rep, 2020
Gao S, Liu L, Zhu S, Wang D, Wu Q, Ning G, Feng S.   +6 more
europepmc   +1 more source

Effect of Fiber Diameter on the Spreading, Proliferation and Differentiation of Chondrocytes on Electrospun Chitosan Matrices [PDF]

, 2011
Sandra Noriega, Gulnara Hasanova, Min Jeong Schneider, Gustavo Larsen, Anuradha Subramanian   +4 more
openalex   +1 more source

Deciphering the skeletal interoceptive circuitry to control bone homeostasis

BMEMat, EarlyView.
This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu, Jiusi Guo, Zhen Chen, Fengwei Zhang, Billy Kwok Chong Chow, Zhuofan Chen, Kelvin Wai‐Kwok Yeung, Wei Qiao   +7 more
wiley   +1 more source

Let-7a-5p derived from parathyroid hormone (1-34)-preconditioned BMSCs exosomes delays the progression of osteoarthritis by promoting chondrocyte proliferation and migration. [PDF]

Stem Cell Res Ther
Shao L, Ding L, Li W, Zhang C, Xia Y, Zeng M, Ye Z, Deng DYB.   +7 more
europepmc   +1 more source

Shox2 is required for chondrocyte proliferation and maturation in proximal limb skeleton

, 2007
Ling Yu, Hongbing Liu, Mingquan Yan, Jing Yang, Fanxin Long, Ken Muneoka, Yi‐Ping Chen   +6 more
openalex   +1 more source

Optimizing biophysical properties of cellular niches to enhance stem cell‐derived extracellular vesicle function in musculoskeletal regeneration

BMEMat, EarlyView.
Extracellular vesicles (EVs) derived from stem cells show promise for applications in regenerative medicine, but their scalability and yield remain challenges. This review explores the approaches for biophysical modulations within cell niches on EV properties, discusses the current clinical application of EVs, and provides an outlook on the existing ...
Yang Xu, Chung Yin Matthew Cheung, Liling Liu, Hoi Pan Harry Cheung, Kam Yu Tam, Dai Fei Elmer Ker, Sarah H. Cartmell, Chuanbin Mao, Zhiyong Zhang, Dan Michelle Wang   +9 more
wiley   +1 more source

Evaluation of triply periodic minimal surface geometries in 3D‐printed PLA scaffolds for chondrogenic differentiation

Biotechnology Progress, EarlyView.
Abstract Triply periodic minimal surface (TPMS) scaffolds are gaining attention in tissue engineering due to their continuous and interconnected porous architecture. In this study, three TPMS geometries—Gyroid, Diamond, and I‐WP—were fabricated from polylactic acid (PLA) using fused deposition modeling (FDM), with all scaffolds designed to maintain the
Mahmut Alp Kılıç, Mustafa Akyürek, Roozbeh Abidnejad, Alp Karakoç   +3 more
wiley   +1 more source

MiR-322-5p is involved in regulating chondrocyte proliferation and differentiation in offspring's growth plate of maternal gestational diabetes. [PDF]

Sci Rep
Qian F, Chen X, Wang S, Zhong Y, Liu M, Wang G, Yang X, Cheng X.   +7 more
europepmc   +1 more source

Hsa_circularRNA_0079201 suppresses chondrocyte proliferation and endochondral ossification by regulating the microRNA‑140‑3p/SMAD2 signaling pathway in idiopathic short stature. [PDF]

Int J Mol Med, 2020
Liu X, Yan C, Deng X, Jia J.
europepmc   +1 more source