Results 231 to 240 of about 1,182,907 (370)

Altered IHH signaling contributes to reduced chondrocyte proliferation in the growth plate of MPS VII mice. [PDF]

Mol Genet Metab Rep, 2020
Jiang Z, Derrick-Roberts ALK, Byers S.
europepmc   +1 more source

Indian hedgehog Is an Essential Component of Mechanotransduction Complex to Stimulate Chondrocyte Proliferation [PDF]

, 2001
Qiuqian Wu, Yue Zhang, Qian Chen
openalex   +1 more source

Melatonin Exerts Chondroprotective Effects Against Osteoarthritis by Promoting PI3K/AKT/FoxO3‐Mediated Mitophagy

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Osteoarthritis (OA) is a prevalent degenerative joint disease. This study combines bioinformatics analysis with in vivo and in vitro experiments to elucidate the molecular mechanisms through which melatonin (MT) regulates mitophagy to alleviate OA.
Chao Huang, Gang Zhang, Ying‐Kai Ma, Xin‐Nan Ma, Song‐Cen Lv   +4 more
wiley   +1 more source

MicroRNA-197 regulates chondrocyte proliferation, migration, and inflammation in pathogenesis of osteoarthritis by targeting EIF4G2. [PDF]

Biosci Rep, 2020
Gao S, Liu L, Zhu S, Wang D, Wu Q, Ning G, Feng S.   +6 more
europepmc   +1 more source

USP7 Regulates TRPV1 Deubiquitination to Mediate Chondrocyte Ferroptosis and Alleviate Osteoarthritis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Osteoarthritis (OA) is a common degenerative joint disease characterized by chondrocyte dysfunction. In this study, we explored the function and mechanism of ubiquitin‐specific protease 7 (USP7) in chondrocyte ferroptosis in OA. The USP7, TRPV1, collagen II, and GPX4 levels in knee joint tissue were detected using immunohistochemistry ...
Jun Li, Ding Chen, Wei‐Ye Zhong
wiley   +1 more source

Let-7a-5p derived from parathyroid hormone (1-34)-preconditioned BMSCs exosomes delays the progression of osteoarthritis by promoting chondrocyte proliferation and migration. [PDF]

Stem Cell Res Ther
Shao L, Ding L, Li W, Zhang C, Xia Y, Zeng M, Ye Z, Deng DYB.   +7 more
europepmc   +1 more source

Extracellular Vesicle‐Mediated Communication Between Anterior Cruciate Ligament and Bone Marrow Cells Modulates Hamstring Tenocyte Behavior and Apoptosis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Following anterior cruciate ligament (ACL) reconstruction, enhancing hamstring tenocyte activity and minimizing apoptosis are critical for preventing graft failure and promoting ligamentization. This study investigated the therapeutic potential of extracellular vesicles (EVs) derived from a coculture of ACL remnant cells and bone marrow ...
Hon‐Lok Lo, Shih‐Hao Huang, Ting‐Hsuan Dai, Shun‐Cheng Wu, Cheng‐Jung Ho, Cheng‐Chang Lu   +5 more
wiley   +1 more source

CHARACTERIZING AQP9: A REGULATOR OF EPIPHYSEAL PLATE CHONDROCYTE PROLIFERATION, HYPERTROPHY, AND LONG BONE GROWTH

, 2018
Pontius Tang
openalex   +1 more source

Autologous minimally manipulated adipose‐derived stromal vascular fraction in knee osteoarthritis: Lasting symptom relief and imaging evidence from a 12‐month prospective study

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To evaluate the safety and efficacy of intra‐articular autologous transplantation of adipose‐derived connective tissue micrografts rich in stromal vascular fraction (CTM‐SVF), obtained using an enzyme‐free system (Hy‐Tissue® SVF) for knee osteoarthritis (OA). Methods Thirty patients (mean age of 53.3 ± 6.4 years) with Kellgren–Lawrence
Laura Mangiavini, Nicolò Rossi, Riccardo Giorgino, Francesco Borelli, Alessandra Colombini, Paola De Luca, Simona Landoni, Luca Maria Sconfienza, Carmelo Messina, Irene Beriotto, Giuseppe M. Peretti, Laura de Girolamo   +11 more
wiley   +1 more source

MiR-322-5p is involved in regulating chondrocyte proliferation and differentiation in offspring's growth plate of maternal gestational diabetes. [PDF]

Sci Rep
Qian F, Chen X, Wang S, Zhong Y, Liu M, Wang G, Yang X, Cheng X.   +7 more
europepmc   +1 more source