Results 71 to 80 of about 1,182,907 (370)

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Syndecan-3 Is a Selective Regulator of Chondrocyte Proliferation [PDF]

Journal of Biological Chemistry, 2002
Chondrocyte proliferation is important for skeletal development and growth, but the mechanisms regulating it are not completely clear. Previously, we showed that syndecan-3, a cell surface heparan sulfate proteoglycan, is expressed by proliferating chondrocytes in vivo and that proliferation of cultured chondrocytes in vitro is sensitive to ...
Thorsten, Kirsch, Eiki, Koyama, Mufei, Liu, Ellis E, Golub, Maurizio, Pacifici   +4 more
openaire   +2 more sources

Neural crest cell-derived VEGF promotes embryonic jaw extension [PDF]

, 2015
Jaw morphogenesis depends on the growth of Meckel’s cartilage during embryogenesis. However, the cell types and signals that promote chondrocyte proliferation for Meckel’s cartilage growth are poorly defined.
Christiana Ruhrberg, Francesca E. Mackenzie, Gerber, Peter Anderson, Quenten Schwarz, Samuela Kabbara, Sophie Wiszniak, Thomas   +7 more
core   +1 more source

Composite Electrospun Fibers Containing Optimized B‐ and Cu‐Doped Bioactive Glass Sol‐Gel Particles for Potential Soft Tissue Engineering Applications

Advanced Engineering Materials, EarlyView.
This article describes the preparation and characterization of poly(ε‐caprolactone) electrospun composite fibers incorporating sol‐gel‐derived bioactive glass particles doped with B and Cu. Scanning electron microscopy, energy‐dispersive X‐ray spectroscopy, Fourier‐transform infrared spectroscopy, contact angle, acellular bioactivity, mechanical and ...
Elisa Piatti, Marta Miola, Liliana Liverani, Paolo Sartori, Enrica Verné, Aldo R. Boccaccini   +5 more
wiley   +1 more source

Development of fibrocartilage layers in the anterior cruciate ligament insertion in rabbits

BMC Musculoskeletal Disorders, 2019
Background A detailed evaluation focusing on the fibrocartilage layers in the anterior cruciate ligament (ACL) insertion is necessary to consider regeneration of the insertion.
Hirotaka Mutsuzaki, Hiromi Nakajima, Maika Someji, Masataka Sakane   +3 more
doaj   +1 more source

In vitro ovine articular chondrocyte proliferation: experiments and modelling [PDF]

Cell Proliferation, 2010
AbstractThis study focuses on analysis of in vitro cultures of chondrocytes from ovine articular cartilage. Isolated cells were seeded in Petri dishes, then expanded to confluence and phenotypically characterized by flow cytometry. The sigmoidal temporal profile of total counts was obtained by classic haemocytometry and corresponding cell size ...
MANCUSO, LUISA, Liuzzo MI, FADDA, SARAH, Pisu M, CINCOTTI, ALBERTO, Arras M, LA NASA, GIORGIO, Concas A, CAO, GIACOMO   +8 more
openaire   +4 more sources

Enhanced Tissue Integration During Cartilage RepairIn VitroCan Be Achieved by Inhibiting Chondrocyte Death at the Wound Edge [PDF]

, 2009
Objective: Experimental wounding of articular cartilage results in cell death at the lesion edge. The objective of this study was to investigate whether inhibition of this cell death results in enhanced integrative cartilage repair.
Archer, Charles W., Burdon, Drew, Duance, Victor C., Gilbert, Sophie J., Gonzalez, Lee G., Khan, Ilyas M., Singhrao, Simarjit Kaur, Thomson, Brian M.   +7 more
core   +1 more source

Development and Preliminary In Vivo Study of 3D‐Printed Bioactive Glass Scaffolds with Trabecular Architecture

Advanced Engineering Materials, EarlyView.
This study reports the fabrication of trabecular bioactive glass scaffolds (composition “1d”: 46.1SiO2‐28.7CaO‐8.8MgO‐6.2P2O5‐5.7CaF2‐4.5Na2O wt%) through vat photopolymerization and the relevant results from mechanical testing and in vivo implantation procedures in rabbit femora, showing great promise for bone tissue engineering applications.
Dilshat Tulyaganov, Roberta Gabrieli, Avzal Akbarov, Nigora Nigmatova, Bekhzod Khabilov, Alessandro Schiavi, Martin Schwentenwein, Enrica Verné, Francesco Baino   +8 more
wiley   +1 more source

The Incidence and Clinical Relevance of Graft Hypertrophy After Matrix-Based Autologous Chondrocyte Implantation [PDF]

, 2012
Background: Graft hypertrophy is the most common complication of periosteal autologous chondrocyte implantation (p-ACI). Purpose: The aim of this prospective study was to analyze the development, the incidence rate, and the persistence of graft ...
Annie Horng, Eckstein F, Isa Feist-Pagenstert, Matthias F. Pietschmann, Mehmet F. Gülecyüz, Peter E. Müller, Thomas R. Niethammer, Volkmar Jansson   +7 more
core   +1 more source

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source