Results 1 to 10 of about 95,525 (355)

Heterologous production of chondroitin

Biotechnology Reports, 2022
Chondroitin sulfate (CS) is a glycosaminoglycan with a broad range of applications being a popular dietary supplement for osteoarthritis. Usually, CS is extracted from animal sources.
Márcia R. Couto, Joana L. Rodrigues, Lígia R. Rodrigues   +2 more
doaj   +4 more sources

Interaction of Chondroitin and Hyaluronan Glycosaminoglycans with Surfaces of Carboxylated Carbon Nanotubes Studied Using Molecular Dynamics Simulations

Molecules, 2023
Interaction of β-D-glucopyranuronic acid (GlcA), N-acetyl-β-D-glucosamine (GlcNAc), N-acetyl-β-D-galactosamine (GalNAc) and two natural decameric glycosaminoglycans, hyaluronic acid (HA) and Chondroitin (Ch) with carboxylated carbon nanotubes, were ...
Tomasz Panczyk, Wojciech Plazinski, François-Yves Dupradeau, Agnieszka Brzyska, Pawel Wolski   +4 more
doaj   +1 more source

Enzymatic Production of Chondroitin Oligosaccharides and Its Sulfate Derivatives

Frontiers in Bioengineering and Biotechnology, 2022
Chondroitin sulfate (CS) has a wide range of physiological functions and clinical applications. However, the biosynthesis of chondroitin oligosaccharides (o-CHs) and sulfate derivatives with specific length is always challenging.
Weijiao Zhang, Weijiao Zhang, Weijiao Zhang, Ruirui Xu, Ruirui Xu, Xuerong Jin, Xuerong Jin, Yang Wang, Yang Wang, Litao Hu, Litao Hu, Tianmeng Zhang, Tianmeng Zhang, Guocheng Du, Guocheng Du, Zhen Kang, Zhen Kang   +16 more
doaj   +1 more source

Gastroprotective Effects of Oral Glycosaminoglycans with Sodium Alginate in an Indomethacin-Induced Gastric Injury Model in Rats

Veterinary Sciences, 2023
The gastrointestinal (GI) mucosal barrier is often exposed to inflammatory and erosive insults, resulting in gastric lesions. Glycosaminoglycans (GAGs), such as hyaluronic acid (HA), chondroitin sulfate (CS), and N-acetylglucosamine (NAG) have shown ...
Sara Traserra, Héctor Cuerda, Adriana Vallejo, Sergi Segarra, Roger Sabata, Marcel Jimenez   +5 more
doaj   +1 more source

Nutrition and dietary supplements in the prevention of osteoarthritis [PDF]

Arhiv za farmaciju, 2016
Optimally balanced diet in order to body weight control in combination with adequate physical activity has an important role in the prevention of degenerative joint disorders.
Vidović Bojana, Đorđević Brižita
doaj   +1 more source

Osteoarthritis background therapy: current view on the glucosamine and chondroitin therapy

Современная ревматология, 2021
The article highlights the current status of symptomatic slow-acting drugs (SYSADOA) in osteoarthritis (OA). Mechanism of action, clinical studies data on the effectiveness of glucosamine (GA) and chondroitin sulfate (CS) and their combinations in OA ...
L. I. Alekseeva, A. M. Lila
doaj   +1 more source

Efficacy and safety of the combined use of celecoxib, diacerein and a combination of glucosamine and chondroitin for the control of musculoskeletal pain associated with osteoarthritis and nonspecific back pain

Современная ревматология, 2023
The combined use of drugs with different mechanisms of action is the main principle of musculoskeletal pain control in rheumatic diseases. However, there are few studies evaluating the efficacy of this approach in real practice.Objective: to determine ...
A. E. Karateev, E. Yu. Polishchuk, A. M. Lila, A. N. Ananyev, L. V. Ananyeva, A. V. Bondarev, A. A. Bondareva, A. R. Bukanbaeva, S. V. Vorster, S. A. Gadzhieva, D. G. Danilov, R. I. Eliseev, I. S. Zabelin, M. Yu. Ignatenko, I. V. Itkina, A. E. Kolesnikov, M. Yu. Konoplyanskaya, Yu. G. Krasnoyarova, S. I. Kukushkin, V. A. Lila, O. V. Makareva, V. S. Myagkikh, I. V. Nelgovskaya, N. V. Ocheredko, R. A. Panov, I. A. Polyakov, A. S. Prozorov, S. S. Rubina, M. E. Ryabochkina, M. A. Takhaev, E. R. Tokareva, T. V. Tolbina, M. I. Fominykh, V. V. Tsarev, E. I. Sharipova, M. V. Sheven, G. I. Shcherbakov, S. A. Yanchenkova   +37 more
doaj   +1 more source

Chondroitin Sulfate Protects the Liver in an Experimental Model of Extra-Hepatic Cholestasis Induced by Common Bile Duct Ligation

Molecules, 2022
During liver fibrogenesis, there is an imbalance between regeneration and wound healing. The current treatment is the withdrawal of the causing agent; thus, investigation of new and effective treatments is important.
Pedro L. R. Guedes, Carolina P. F. Carvalho, Adriana A. F. Carbonel, Manuel J. Simões, Marcelo Y. Icimoto, Jair A. K. Aguiar, Maria Kouyoumdjian, Marcos L. Gazarini, Marcia R. Nagaoka   +8 more
doaj   +1 more source

The use of dietary supplements supporting functioning of musculoskeletal system in rehabilitation clinic patients

Annales Academiae Medicae Silesiensis, 2022
Introduction Musculoskeletal conditions are often characterized by pain, as well as limited physical function. To alleviate pain accompanying musculoskeletal diseases, non-steroidal anti-inflammatory drugs (NSAIDs) and/or paracetamol are used.
Paulina Pluta, Weronika Osmala-Kurpiewska, Agata Piekut   +2 more
doaj   +1 more source

Misincorporation of Galactose by Chondroitin Synthase of Escherichia coli K4: From Traces to Synthesis of Chondbiuronan, a Novel Chondroitin-Like Polysaccharide

Biomolecules, 2020
Chondroitin synthase KfoC is a bifunctional enzyme which polymerizes the capsular chondroitin backbone of Escherichia coli K4, composed of repeated β3N-acetylgalactosamine (GalNAc)-β4-glucuronic acid (GlcA) units. Sugar donors UDP-GalNAc and UDP-GlcA are
Mélanie Leroux, Julie Michaud, Eric Bayma, Sylvie Armand, Sophie Drouillard, Bernard Priem   +5 more
doaj   +1 more source