Results 131 to 140 of about 91,886 (318)

Holothurian Fucosylated Chondroitin Sulfate [PDF]

Marine Drugs, 2014
Fucosylated chondroitin sulfate (FucCS) is a structurally distinct glycosaminoglycan found in sea cucumber species. It has the same backbone composition of alternating 4-linked glucuronic acid and 3-linked N-acetyl galactosamine residues within disaccharide repeating units as regularly found in mammalian chondroitin sulfates.
openaire   +4 more sources

Reprogramming Metabolic Flux in Escherichia Coli to Enhance Chondroitin Production

Advanced Science
Reprogramming metabolic flux is a promising approach for constructing efficient microbial cell factories (MCFs) to produce chemicals. However, how to boost the transmission efficiency of metabolic flux is still challenging in complex metabolic pathways ...
Chunlei Zhao, Xiaomin Li, Liang Guo, Cong Gao, Wei Song, Wanqing Wei, Jing Wu, Liming Liu, Xiulai Chen   +8 more
doaj   +1 more source

Reduced Accumulation Rate and Morphological Changes of Newly Generated Myelinating Oligodendrocytes in the Corpus Callosum of Aged Mice

Glia, EarlyView.
Newly generated myelinating oligodendrocyte accumulation is decreased in the corpus callosum of aged mice. Morphological changes of newly generated myelinating oligodendrocytes in aged mice: greater height, shorter, and fewer myelin sheaths. ABSTRACT The activity of oligodendrocyte progenitor cells (OPCs) and oligodendrocytes (OLs) throughout life ...
Sasikarn Looprasertkul, Reiji Yamazaki, Yasuyuki Osanai, Nobuhiko Ohno   +3 more
wiley   +1 more source

Olig2/Plp-positive progenitor cells give rise to Bergmann glia in the cerebellum. [PDF]

, 2013
NG2 (nerve/glial antigen2)-expressing cells represent the largest population of postnatal progenitors in the central nervous system and have been classified as oligodendroglial progenitor cells, but the fate and function of these cells remain ...
Chung, S-H, Deng, W, Guo, F, Jiang, P, Pleasure, DE   +4 more
core   +2 more sources

Isolation of an Escherichia coli K4 kfoC mutant over-producing capsular chondroitin

Microbial Cell Factories, 2010
Background Chondroitin sulphate is a complex polysaccharide having important structural and protective functions in animal tissues. Extracted from animals, this compound is used as a human anti-inflammatory drug.
De Rosa Mario, Schiraldi Chiara, Cimini Donatella, Notomista Eugenio, Restaino Odile F, Zanfardino Anna, De Felice Maurilio, Varcamonti Mario   +7 more
doaj   +1 more source

Unraveling the Role of Ensheathing Cells and Perineural Fibroblasts in Olfactory Neurogenesis

Glia, EarlyView.
OECs are similar to satellite glial cells. OECs react to neuronal injury by promoting lipid metabolism, but do not proliferate. OECs reduce gap junctions upon neuronal injury. Perineural fibroblasts also contribute to the injury response. ABSTRACT During development and following injury‐induced neurogenesis, olfactory ensheathing cells (OECs) envelope ...
Katja Senf, Sandor Nietzsche, Martin Westermann, Eva M. Neuhaus   +3 more
wiley   +1 more source

Glucosamine and chondroitin for the treatment of osteoarthritis

World Journal of Orthopedics, 2017
The prevalence of primary or idiopathic osteoarthritis (OA) of knee and hip joints has substantially increased in general population during the last decades. Analgesics and non-steroidal anti-inflammatory drugs are currently extensively used as non-surgical treatment options.
Konstantinos Tsikopoulos, Haris S. Vasiliadis   +1 more
openaire   +3 more sources

Discrepancies in Composition and Biological Effects of Different Formulations of Chondroitin Sulfate

Molecules, 2015
Osteoarthritis is a common, progressive joint disease, and treatments generally aim for symptomatic improvement. However, SYmptomatic Slow-Acting Drugs in Osteoarthritis (SYSADOAs) not only reduce joint pain, but slow structural disease progression.
Johanne Martel-Pelletier, Aina Farran, Eulàlia Montell, Josep Vergés, Jean-Pierre Pelletier   +4 more
doaj   +1 more source

Immunomodulatory natural polysaccharide‐based nanoparticles for the treatment of neurodegenerative diseases

Ibrain, EarlyView.
Polysaccharide‐based nanoparticles offer versatile platforms for drug delivery and immune modulation in neurodegenerative diseases. This review highlights their potential in treating Alzheimer's, Parkinson's, and multiple sclerosis, focusing on targeted delivery and neuroinflammation.
Leto‐Aikaterini Tziveleka, Mariafrancesca Cascione, Paolo Pellegrino, Annalisa Bianco, Stefano Leporatti, Valeria De Matteis   +5 more
wiley   +1 more source

Generation and functional analysis of melanoma antigen‐specific CD8+ T cells derived from S/MAR vector‐transfected human induced pluripotent stem cells

International Journal of Cancer, EarlyView.
What's New? Adoptive cell therapy (ACT) with tumor antigen‐specific CD8+ T cells has shown success in clinical trials treating patients with advanced or metastatic melanoma. Here, the authors established protocols for generating CD8+ T cells from human induced pluripotent stem cells (hiPSCs) expressing a melanoma‐specific T cell receptor (TCR) or ...
Juliane Poelchen, Sandra Pardo, Daniel Novak, Qian Sun, Tamara Steinfass, Marlene Vierthaler, Özge Cicek Sener, Karol Granados Blanco, Yiman Wang, Jan Peter Nicolay, Pierre Guermonprez, Richard Harbottle, Viktor Umansky, Jochen Utikal   +13 more
wiley   +1 more source