Results 131 to 140 of about 95,525 (355)

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

BMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou, Jia Liu, Shulin Lai, Suhan Yin, Bingmin Luo, Longquan Shao, Yiyuan Kang   +6 more
wiley   +1 more source

Porous Organic Frameworks‐Based Nanomaterials in Colorectal Cancer Therapy: From Drug Delivery to Personalized Nano‐Vaccine

Cancer Nexus, EarlyView.
ABSTRACT Colorectal cancer (CRC), as the second most common cause of cancer death worldwide, has seen a significant increase in its incidence rate in recent years. However, the current major clinical treatment methods, such as surgery, chemotherapy and radiotherapy, still have certain limitations and are difficult to achieve a complete cure.
Xiaoyu Song, Hao Zhang, Yinghui Wang, Chao Luo   +3 more
wiley   +1 more source

Efficacy and safety of prednisolone and chloroquine Add on therapy in osteoarthritis of the knee treated with fixed Dose combination of Glucosamine and chondroitin sulfate [PDF]

Background & ObjectiveOsteoarthritis is the most common type of joint disorder and also the main reason to consult Rheumatologists. Furthermore, a high level of weakness especially among elderly is due to OA.
بهلولی, شهاب, جستان, مارینا, قربانی, مریم   +2 more
core  

Identification of Chondroitin Sulfate Glucuronyltransferase as Chondroitin Synthase-3 Involved in Chondroitin Polymerization [PDF]

Journal of Biological Chemistry, 2008
Tomomi Izumikawa, Toshiyasu Koike, Shoko Shiozawa, Kazuyuki Sugahara, Jun-ichi Tamura, Hiroshi Kitagawa   +5 more
openaire   +1 more source

The endocannabinoid system regulates both ependymoglial and neuronal cell responses to a tail amputation in the axolotl

Developmental Dynamics, EarlyView.
Abstract Background The endocannabinoid system is a neuromodulatory system implicated in cellular processes during both development and regeneration. The Mexican axolotl, one of only a few vertebrates capable of central nervous system regeneration, was used to examine the role of the endocannabinoid system in the regeneration of the tail and spinal ...
Michael Tolentino, Sarah E. Walker, Gaynor E. Spencer, Robert Carlone   +3 more
wiley   +1 more source

Lueyang Black‐Boned Chicken and Black Bean Soup Promoting the Acute Healing of Skin Wounds, Accompanying Special Flavor Substances

Food Chemistry International, EarlyView.
ABSTRACT Animal protein and plant protein make the protein supplement more comprehensive and further optimize the nutritional structure of the national diet. In this study, a “dual protein” Lueyang black‐boned chicken and black bean soup (FS) was prepared.
Mengya Zhao, Zining Luo, Pengyan Tong, Yining Jia, Xin Yang, Jing Liu, Fangyu Long   +6 more
wiley   +1 more source

Profiling of Extracellular Vesicles of Non-Small Cell Lung Cancer Reveals Proteins Associated With Osimertinib Resistance. [PDF]

J Extracell Vesicles
Non‐invasive biomarkers are needed to further personalize EGFR tyrosine kinase inhibitor (EGFR TKI) osimertinib treatment in non‐small cell lung cancer (NSCLC) patients. By analysing the proteome of extracellular vesicles (EVs) isolated from an osimertinib resistant NSCLC cell line and from serum of patients given osimertinib in second line within the ...
Cáceres-Verschae A, Hååg P, Joelsson S, Hydbring P, Franzén B, Végvári Á, Eide IJZ, Agarwal N, Sahu SS, Stridfeldt F, De Petris L, Dev A, Ekman S, Brustugun OT, Lewensohn R, Viktorsson K.   +15 more
europepmc   +2 more sources

Impact of Glucosamin and Chondroitin Sulfates Combination (GCSC) on the Burden of Osteorthritis over 6 Months in Portugal: An Observational Study [PDF]

, 2016
Heidi Mateus, Anderson do Rego Pires, A Zkik, G Berdeaux, M. Augès, R Hemery   +5 more
openalex   +1 more source

Ciprofloxacin Treatment in Juvenile Mice Involves Neuronal Activation and Mimics Physical Features of Human Disease

Journal of Orthopaedic Research, EarlyView.
ABSTRACT Tendinopathy is a complex, painful condition that affects up to 5% of the general population in their lifetime. Antibiotic treatment with fluoroquinolones has been associated with the onset of tendinopathy and tendon rupture. The mechanisms behind fluoroquinolone induced tendinopathy remain unclear. To probe activation of potentially causative
Nicole A. Chittim, Amro A. Hussien, Nicolo Dubacher, Gabor Matyas, Jess G. Snedeker   +4 more
wiley   +1 more source

Endogenous chondroitin extends lifespan by inhibiting VHA-7-mediated tubular lysosome formation

Scientific Reports
Chondroitin extends lifespan and healthspan in C. elegans, but the relationship between extracellular chondroitin and intracellular anti-aging mechanisms is unknown.
Yukimasa Shibata, Yuri Tanaka, Shunsuke Mori, Kaito Mitsuzumi, Shion Fujii, Hiroyuki Sasakura, Yuki Morioka, Kenji Sugioka, Kosei Takeuchi, Kiyoji Nishiwaki   +9 more
doaj   +1 more source