Results 21 to 30 of about 89,429 (244)
Introduction Musculoskeletal conditions are often characterized by pain, as well as limited physical function. To alleviate pain accompanying musculoskeletal diseases, non-steroidal anti-inflammatory drugs (NSAIDs) and/or paracetamol are used.
Paulina Pluta+2 more
doaj +1 more source
During liver fibrogenesis, there is an imbalance between regeneration and wound healing. The current treatment is the withdrawal of the causing agent; thus, investigation of new and effective treatments is important.
Pedro L. R. Guedes+8 more
doaj +1 more source
Statistical method for analysis of interactions between chosen protein and chondroitin sulfate in an aqueous environment [PDF]
We present the statistical method to study the interaction between a chosen protein and another molecule (e.g., both being components of lubricin found in synovial fluid) in a water environment. The research is performed on the example of univariate time series of chosen features of the dynamics of mucin, which interact with chondroitin sulfate (4 and ...
arxiv +1 more source
The combined use of drugs with different mechanisms of action is the main principle of musculoskeletal pain control in rheumatic diseases. However, there are few studies evaluating the efficacy of this approach in real practice.Objective: to determine ...
A. E. Karateev+37 more
doaj +1 more source
Osteoarthritis background therapy: current view on the glucosamine and chondroitin therapy
The article highlights the current status of symptomatic slow-acting drugs (SYSADOA) in osteoarthritis (OA). Mechanism of action, clinical studies data on the effectiveness of glucosamine (GA) and chondroitin sulfate (CS) and their combinations in OA ...
L. I. Alekseeva, A. M. Lila
doaj +1 more source
Analysis of Chondroitin/Dermatan Sulphate Disaccharides Using High-Performance Liquid Chromatography
Chondroitin sulphates belong to a group of naturally occurring glycosaminoglycans and play a role in many physiological processes including ageing and the effects of various diseases.
Ivan Mikšík+7 more
doaj +1 more source
Endogenous chondroitin extends lifespan by inhibiting VHA-7-mediated tubular lysosome formation. [PDF]
Chondroitin extends lifespan and healthspan in C. elegans, but the relationship between extracellular chondroitin and intracellular anti-aging mechanisms is unknown.
Shibata Y+9 more
europepmc +2 more sources
The optimal way to fill the deficiency of essential substances for the well-being of the joints
The article presents basic information about the role and structure of cartilage tissue and its components, the impact of an imbalance in the structure of nutrition on the well-being of the joints, evidence of the symptomatic and structural-modifying ...
I. S. Dydykina+3 more
doaj +1 more source
Chondroitin Sulfate and Its Derivatives: A Review of Microbial and Other Production Methods
Chondroitin sulfate (CS) is widely used across the world as a nutraceutical and pharmaceutical. Its high demand and potential limitations in current methods of extraction call for an alternative method of production.
Adeola E. Awofiranye+5 more
doaj +1 more source
Comparative study of osteogenic activity of multilayers made of synthetic and biogenic polyelectrolytes [PDF]
Polyelectrolyte multilayer (PEM) coatings on biomaterials are applied to tailor adhesion, growth, and function of cells on biomedical implants. Here, biogenic and synthetic polyelectrolytes (PEL) are used for layer-by-layer assembly to study the ...
Gonzalez-Garcia, Cristina+4 more
core +1 more source