Results 111 to 120 of about 30,507 (276)
Targeting Chondroitin Sulfate Proteoglycans: An Emerging Therapeutic Strategy to Treat CNS Injury [PDF]
, 2020 Nabanita Mukherjee +9 more
openalex +1 more source
The FEBS Journal, EarlyView.Zebrafish Tgds, when expressed as a recombinant protein, catalyzes the dehydration of UDP‐D‐glucose, the initial step in the formation of 6‐deoxyhexoses. Corresponding Tgds mutations found in Catel–Manzke syndrome patients lead to reduced enzymatic activity and stability.
Maria Rosaria Coppola +11 more
wiley +1 more source
Human Proteoglycan Linkage Region Glycosyltransferases are Dimeric and Show Unexpected Specificities
Angewandte Chemie, Volume 138, Issue 3, 16 January 2026.Non‐canonical glycopeptides of the proteoglycan linkage region are accessible by the enzymes B3GalT6 and GlcAT‐1 confirming a recently discovered rescue mode in glycosaminoglycan (GAG) biosynthesis. The crystal structure of B3GalT6 revealed a covalent dimer linked by a disulfide. Abstract We selected the N,O‐glycosylated proteoglycan bikunin as a model
Sascha Weidler +16 more
wiley +2 more sources
Anais Brasileiros de Dermatologia, 2005 FUNDAMENTOS: O líquen escleroso (LS) apresenta zona de hialinização do colágeno na derme superior característica, que persiste pouco definida do ponto de vista morfológico e cujo significado permanece sem explicação.
Adriana de Carvalho Corrêa +4 more
doaj +1 more source
Journal of Anatomy, Volume 246, Issue 4, Page 585-601, April 2025.The extracellular matrix plays a critical role in modulating cell behaviour in the central nervous system influencing neural cell morphology and growth. However, a better understanding of the impact of individual matrix proteins on both neurons and astrocytes is critical for advancing the development of matrix‐based neural repair strategies.
Cian O'Connor +9 more
wiley +1 more source
Sulodexide. Nephroprotective properties and horizons for use in nephrology
Медицинский совет, 2015 Sulodexide belongs to the class of glycosaminoglycans (GAGs) or mucopolysaccharides. Found in mammalian tissuesm, GAGs regulate the activity of a wide range of proteins (including chemokines, cytokines, growth factors, enzymes, morphogens, and adhesion ...
M. M. Batyushin
doaj +1 more source
End-functionalized glycopolymers as mimetics of chondroitin sulfate proteoglycans [PDF]
, 2010 Glycosaminoglycans are sulfated polysaccharides that play important roles in fundamental biological processes, such as cell division, viral invasion, cancer and neuroregeneration.
Brown, Joshua M. +6 more
core +2 more sources
Collagen organisation in the fibrous joint capsules in the digits of the human hand
Journal of Anatomy, EarlyView.The function of the finger joints is important for daily life. In this review of the literature, we consider the role of collagen and its organization within the fibrous finger joint capsules of the interphalangeal (IP) joints and investigate the relationships between collagen orientation and joint function. Abstract Normal function of the hand and, in
Fiona R. Saunders +3 more
wiley +1 more source
Blood platelets stimulate the expression of chondroitin sulfate proteoglycan in human monocytes [PDF]
, 1992 Lars Uhlin‐Hansen +3 more
openalex +3 more sources
Transforming growth factor-b regulation of proteoglycan synthesis in vascular smooth muscle: Contribution to lipid binding and accelerated atherosclerosis in diabetes [PDF]
, 2010 Atherosclerosis is accelerated in the setting of diabetes, but the factors driving this phenomenon remain elusive. Hyperglycemia leads to elevated levels of transforming growth factor (TGF)-b and TGF-b has been implicated as a factor in atherosclerosis ...
Burch, M +5 more
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