Results 11 to 20 of about 15,622 (209)
Contributions of chondroitin sulfate proteoglycans to neurodevelopment, injury, and cancer. [PDF]
Curr Opin Neurobiol, 2014 Chondroitin sulfate proteoglycans (CSPGs) are a diverse family of extracellular matrix (ECM) molecules that make significant contributions to the patterning and routing of migrating neural cells and extending axons. Three distinct modes of migration mediation result from the relative abundance and positioning of expressed CSPGs, the profile of CSPG ...
Silver DJ, Silver J.
europepmc +4 more sources
Global analysis of neuronal phosphoproteome regulation by chondroitin sulfate proteoglycans. [PDF]
PLoS ONE, 2013 Chondroitin sulfate proteoglycans (CSPGs) are major components of the extracellular matrix which mediate inhibition of axonal regeneration after injury to the central nervous system (CNS).
Panpan Yu +7 more
doaj +2 more sources
Novel Insight Into Glycosaminoglycan Biosynthesis Based on Gene Expression Profiles
Frontiers in Cell and Developmental Biology, 2021 Glycosaminoglycans (GAGs) including chondroitin sulfate, dermatan sulfate, heparan sulfate, and keratan sulfate, except for hyaluronan that is a free polysaccharide, are covalently attached to core proteins to form proteoglycans.
Yi-Fan Huang +2 more
doaj +1 more source
Identification of function-regulating antibodies targeting the receptor protein tyrosine phosphatase sigma ectodomain. [PDF]
PLoS ONE, 2017 Receptor tyrosine phosphatase sigma (RPTPσ) plays an important role in the regulation of axonal outgrowth and neural regeneration. Recent studies have identified two RPTPσ ligands, chondroitin sulfate proteoglycans (CSPGs) and heparan sulfate ...
Chia-Lun Wu +6 more
doaj +1 more source
Congenital Disorders of Deficiency in Glycosaminoglycan Biosynthesis
Frontiers in Genetics, 2021 Glycosaminoglycans (GAGs) including chondroitin sulfate, dermatan sulfate, and heparan sulfate are covalently attached to specific core proteins to form proteoglycans, which are distributed at the cell surface as well as in the extracellular matrix ...
Shuji Mizumoto, Shuhei Yamada
doaj +1 more source
Chondroitin Sulfate Proteoglycans and Neurotrophic Factors
Trends in Glycoscience and Glycotechnology, 2008 Fumiko Matsui
openalex +4 more sources
Biology, 2020 The role of proteoglycans in the central nervous system (CNS) is a rapidly evolving field and has major implications in the field of CNS injury. Chondroitin sulfate proteoglycans (CSPGs) increase in abundance following damage to the spinal cord and ...
Thomas M. Hering +3 more
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Biphasic role of chondroitin sulfate in cardiac differentiation of embryonic stem cells through inhibition of Wnt/β-catenin signaling. [PDF]
PLoS ONE, 2014 The glycosaminoglycan chondroitin sulfate is a critical component of proteoglycans on the cell surface and in the extracellular matrix. As such, chondroitin sulfate side chains and the sulfation balance of chondroitin play important roles in the control ...
Robert D Prinz +3 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 Chondroitin sulfate (CS), dermatan sulfate (DS) and heparan sulfate (HS) are covalently attached to specific core proteins to form proteoglycans in their biosynthetic pathways.
Shuji Mizumoto, Shuhei Yamada
doaj +1 more source
JIMD Reports, 2022 The spondylodysplastic type of Ehlers–Danlos syndrome (spEDS) is caused by genetic defects in the B4GALT7 or B3GALT6 genes both deranging the biosynthesis of the glycosaminoglycan linkage region of chondroitin/dermatan sulfate and heparan sulfate ...
Mahnaz Nikpour +7 more
doaj +1 more source