Ultrasensitive quantification of dextran sulfate by a mix-and-read fluorescent probe assay [PDF]
Dextran sulfate is semi-synthetic, polydisperse sulfated polysaccharide with important applications in clinical practice, in the manufacturing of plasma derived protein therapeutics and in biomedical research. The sensitive detection of dextran sulfate is relevant to preclinical and clinical drug development projects, the quality control of ...
arxiv
Sulodexide. Nephroprotective properties and horizons for use in nephrology
Sulodexide belongs to the class of glycosaminoglycans (GAGs) or mucopolysaccharides. Found in mammalian tissuesm, GAGs regulate the activity of a wide range of proteins (including chemokines, cytokines, growth factors, enzymes, morphogens, and adhesion ...
M. M. Batyushin
doaj +1 more source
Quantification of sulfated polysaccharides in mouse and rat plasma by the Heparin Red mix-and-read fluorescence assay [PDF]
Sulfated polysaccharides constitute a large and complex group of macromolecules which possess a wide range of important biological properties. Many of them hold promise as new therapeutics, but determination of their blood levels during pharmacokinetic studies can be challenging.
arxiv
FUNDAMENTOS: O líquen escleroso (LS) apresenta zona de hialinização do colágeno na derme superior característica, que persiste pouco definida do ponto de vista morfológico e cujo significado permanece sem explicação.
Adriana de Carvalho Corrêa+4 more
doaj +1 more source
Detection of Proteoglycan Loss from Articular Cartilage using Brillouin Microscopy, with Applications to Osteoarthritis [PDF]
The degeneration of articular cartilage (AC) occurs in osteoarthritis (OA), which is a leading cause of pain and disability in middle-aged and older people. The early disease related changes in cartilage extra-cellular matrix (ECM) start with depletion of proteoglycan(PG), leading to an increase in tissue hydration and permeability.
arxiv
During placental malaria, Plasmodium falciparum infected erythrocytes sequester in the placenta, causing health problems for both the mother and fetus.
Marina Ayres Pereira+14 more
doaj +1 more source
Pleiotrophin Signals Through ALK Receptor to Enhance the Growth of Neurons in the Presence of Inhibitory Chondroitin Sulfate Proteoglycans. [PDF]
Gupta SJ+3 more
europepmc +1 more source
Coadsorption of Copper and Sulfate on Au(111) Electrodes: Monte Carlo Simulation of a Lattice-Gas Model [PDF]
We report ground-state calculations and Monte Carlo simulations for a lattice-gas model of the underpotential deposition of copper on Au(111) in sulfate-containing electrolytes. In a potential range of approximately 100$\sim$150 mV, this system exhibits a $(\sqrt3\!\times\!\sqrt3)$ mixed phase with 2/3 monolayer (ML) copper and 1/3 ML sulfate.
arxiv
Membrane-associated chondroitin sulfate proteoglycans of human lung fibroblasts. [PDF]
Gregory David+5 more
openalex +1 more source
Amyloid aggregates found in the brain of patients with neurodegenerative diseases, including Alzheimer’s and Parkinson’s disease, are thought to spread to increasingly larger areas of the brain through a prion-like seeding mechanism.
Elisabet Ihse+5 more
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