Results 171 to 180 of about 8,910 (222)
Some of the next articles are maybe not open access.
Human Chorionic Gonadotropin β-Subunit in Human Semen
Archives of Andrology, 1988The level of human seminal chorionic gonadotropin beta-subunit (hCG beta) was determined by radioimmunoassay (RIA). The mean hCG beta level in 34 normal men was 3.7 +/- 1.6 ng/ml, which was much higher than that in serum. The mean hCG beta level for 20 patients with mild oligozoospermia (20-39 x 10(6) sperm/ml) was 2.5 +/- 0.8 ng/ml, that for 34 ...
S, Saito +3 more
openaire +2 more sources
Immunological properties of the β-subunit of human chorionic gonadotropin
Biochemical and Biophysical Research Communications, 1976Abstract The β-subunit of human chorionic gonadotropin (hCG-β) has been modified to a varying degree by the cleavage of the disulfide bonds by reduction with dithioerythritol followed by S-carboxamidomethylation. The resulting derivatives of hCG-β show a preferential loss in their immunological cross-reactivity with human luteinizing hormone (hLH ...
O P, Bahl, M R, Pandian, R D, Ghai
openaire +2 more sources
Monoclonal Antibody against Freeβ-Subunit of Human Chorionic Gonadotropin
Hybridoma and Hybridomics, 2002Spleen cells from BALB/c mice immunized with free native human chorionic gonadotropin hormone beta-subunit (beta hCG) were fused with mouse myeloma cells (P3/X63-Ag8) and one hybridoma secreting monoclonal antibodies (MAbs), was obtained. This hybridoma specifically recognizes beta hCG and does not cross-react with other human glycoprotein hormones ...
Ileana B, Baluja Conde +7 more
openaire +2 more sources
Mass Spectrometric Characterization of the β-Subunit of Human Chorionic Gonadotropin
Journal of Mass Spectrometry, 1997A high-performance liquid chromatographic/electrospray mass spectrometric (HPLC/MS) technique is described for the characterization of the beta-subunit of the glycopeptide human chorionic gonadotropin (hCG). The beta-subunit of hCG was dissociated from the alpha-subunit using 0.1% trifluoroacetic acid (TFA) and separated by reversed-phase HPLC using a ...
C, Liu, L D, Bowers
openaire +2 more sources
Contraception, 1976
Abstract Four different derivatives with varying proportions of dinitrophenyl (DNP) groups tagged covalently to β-subunit of HCG (DNP (1) -β-HCG, DNP (3.3) -β-HCG, DNP (6) -β-HCG and DNP (10) -β-HCG) have been prepared. Their immunogenicity as well as the reactivity of antibodies formed in mice, rabbit and rhesus monkey have been studied.
S K, Dubey +3 more
openaire +2 more sources
Abstract Four different derivatives with varying proportions of dinitrophenyl (DNP) groups tagged covalently to β-subunit of HCG (DNP (1) -β-HCG, DNP (3.3) -β-HCG, DNP (6) -β-HCG and DNP (10) -β-HCG) have been prepared. Their immunogenicity as well as the reactivity of antibodies formed in mice, rabbit and rhesus monkey have been studied.
S K, Dubey +3 more
openaire +2 more sources
Journal of Reproductive Immunology, 1996
The feasibility of producing epitope-specific antigens by mutation of the gene is demonstrated, the aim being to eliminate unwanted surface epitopes yet allowing the natural folding of the protein to maintain the desired epitope(s). The model protein is the beta subunit of human chorionic gonadotropin (hCG beta) which previously has been used as an ...
A M, Jackson +7 more
openaire +2 more sources
The feasibility of producing epitope-specific antigens by mutation of the gene is demonstrated, the aim being to eliminate unwanted surface epitopes yet allowing the natural folding of the protein to maintain the desired epitope(s). The model protein is the beta subunit of human chorionic gonadotropin (hCG beta) which previously has been used as an ...
A M, Jackson +7 more
openaire +2 more sources
Expression of α- and β-human chorionic gonadotropin subunits in cultured human cells
In Vitro Cellular & Developmental Biology, 1990We surveyed several human cell lines for production of alpha- and beta-human chorionic gonadotropin (hCG) under a variety of conditions known to induce gene expression. alpha- and beta-hCG subunits were monitored in culture media by specific radioimmunoassays and were shown to be quite sensitive to serum refeeding and growth state of all cell types ...
S, Goldstein +4 more
openaire +2 more sources
The Expression of the Human Chorionic Gonadotropin Beta Subunit Gene Depends on Negative Control
Cell Biochemistry and Function, 1996AbstractTranscription of the human chorionic gonadotropin (hCG) genes begins in the very early embryo stage and decreases or even disappears in nonplacental tissues. We have studied the regulation of hCG‐beta genes by cell fusion and by the reverse transcription‐polymerase chain reaction (RT‐PCR).
Y H, Chen, T M, Chen, C Y, Hsieh
openaire +2 more sources
Human chorionic gonadotropin: Amino acid sequence of the α and β subunits
Biochemical and Biophysical Research Communications, 1972Summary The linear amino acid sequences of the α and β subunits of human chorionic gonadotropin have been determined. HCG-α has 92 and HCG-β 139 amino acid residues. There is more homology between HCG-α and ovine LH-α than between HCG-β and ovine LH-β.
O P, Bahl +3 more
openaire +2 more sources