Results 181 to 190 of about 8,259,227 (215)

Evolution of the genes for the β subunits of human chorionic gonadotropin and luteinizing hormone

Nature, 1984
Nucleotide sequence comparisons of the single gene for the human luteinizing hormone gene beta subunit with two of the seven genes for the human chorionic gonadotropin beta subunit suggest that the beta human chorionic gonadotropin genes have evolved from an ancestral beta luteinizing hormone gene by a series of selected changes with very little ...
K, Talmadge, N C, Vamvakopoulos, J C, Fiddes   +2 more
openaire   +2 more sources

A Radioimmunoassay for the Core Fragment of the Human Chorionic Gonadotropinβ-Subunit

The Journal of Clinical Endocrinology & Metabolism, 1988
We developed a RIA for the beta-core fragment of hCG that is excreted in the urine of pregnant women and some patients with cancer. We purified beta-core from crude commercial preparations of hCG (of which beta-core is a major constituent) derived from pregnancy urine and used this purified beta-core material to immunize rabbits.
A H, Akar, R E, Wehmann, D L, Blithe, C, Blacker, B C, Nisula   +4 more
openaire   +2 more sources

Detection and Quantitation of the β-Subunit of Human Chorionic Gonadotropin in Serum by Radioimmunoassay

Fertility and Sterility, 1980
Qualitative and quantitative radioimmunoassays (RIA) specific for the beta-subunit of human chorionic gonadotropin (HCG) produced by Wampole Laboratories and Monitor Science Corporation were compared in a study involving the sera from 213 individuals. Qualitative assays from both manufacturers were found to be equivalent in clinical specificity (99.2%).
W L, Boyko, B, Barrett
openaire   +2 more sources

[Monoclonal antibodies against the beta subunit of human chorionic gonadotropin].

Biulleten' eksperimental'noi biologii i meditsiny, 1989
The aim of investigation was creation of hybridomas, which produce monoclonal antibodies to the beta-subunit of human chorionic gonadotropin (beta-hCG), characterization of monoclonal antibodies, which necessary for hCG immunoassay in biological fluids, as an immunological methods of detection of early stage of pregnancy and choriocarcinoma.
R, Fidler, A V, Sokolov, M Sh, Verbitskiĭ, I P, Papazov   +3 more
openaire   +1 more source

Monoclonal antibodies to human chorionic gonadotropin and its beta-subunit.

Nihon Sanka Fujinka Gakkai zasshi, 1984
Using the technique of somatic cell fusion, monoclonal antibodies to human chorionic gonadotropin (hCG) and its beta-subunit were produced. Spleen cells from immunized mice were fused with the myeloma line NS-1 using 50% polyethylene glycol and cultured in a selection medium.
Y, Furuhashi, H, Mano, S, Hattori, S, Goto, Y, Tomoda   +4 more
openaire   +1 more source

Quantitation of whole molecule human chorionic gonadotropin and free beta-human chorionic gonadotropin subunit in the Abbott IMx analyser.

European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies, 1991
An assay for the quantitation of the serum levels of free and whole molecule-associated beta-subunit of human chorionic gonadotropin on the Abbott IMx analyzer is described. The assay detects human beta-chorionic gonadotropin with a sensitivity of approximately 0.5 IU/l while showing no cross-reactivity with follitropin (1000 IU/l) or thyrotropin (2.0 ...
S D, Figard, J B, Bodner, D M, Babik, D M, Mlyniec, B, Simpson, M, Venetucci, E A, Ogunro   +6 more
openaire   +1 more source

Free human chorionic gonadotropin beta subunit in gonadal and nongonadal neoplasms.

Cancer research, 1992
The diagnostic value of elevated human chorionic gonadotropin (hCG) and its free alpha (hCG alpha) and beta (hCG beta) subunit serum levels as specific tumor markers for nongonadal malignancies is controversial. In the present report, different monoclonal based immunoradiometric assays specific for hCG and its free hCG alpha and hCG beta subunits have ...
I, Marcillac, F, Troalen, J M, Bidart, P, Ghillani, V, Ribrag, B, Escudier, B, Malassagne, J P, Droz, C, Lhommé, P, Rougier   +9 more
openaire   +1 more source

[The value of determination of human chorionic gonadotropin beta subunit in extrauterine pregnancies].

Orvosi hetilap, 1989
The authors deal with the value of the avidin-biotin enzyme immunoassay (A-B-Elisa) which was introduced by them for the demonstration of human chorion gonadotropin beta subunit (HCG-b). It is pointed out that the possibility of the diagnosis of extrauterine pregnancy improved significantly by measuring the HCG-b level with A-B-ELISA method.
B, Pejtsik, S, Pácsa, J, Kóbor
openaire   +1 more source

Immunological Specificity of the β Subunit of the Human Chorionic Gonadotropin (HCG)

Hormone and Metabolic Research, 1974
J, Dolais-Kitabgi, M, Laburthe, G, Rosselin   +2 more
openaire   +2 more sources

Human chorionic gonadotropin (beta-subunit) in the early diagnosis of ectopic pregnancy.

Obstetrics and gynecology, 1978
In 15 women with suspected ectopic pregnancy considerable amounts of beta-subunit of human chorionic gonadotropin (hCG) were detected in the serum by the radioimmunoassay technique. The diagnosis was proved by laparotomy. In another 25 suspected cases beta-hCG values were less than 1 mU/ml, and in those cases the diagnosis was excluded.
A, Milwidsky, A, Adoni, M, Miodovnik, S, Segal, Z, Palti   +4 more
openaire   +1 more source