Evolution of placental function in mammals:the molecular basis of gas and nutrient transfer, hormone secretion, and immune responses [PDF]
Placenta has a wide range of functions. Some are supported by novel genes that have evolved following gene duplication events while others require acquisition of gene expression by the trophoblast.
Carter, Anthony Michael
core +1 more source
Assignment of disulfide bonds in the beta subunit of human chorionic gonadotropin.
The assignment of five disulfide bonds in the alpha subunit of human chorionic gonadotropin (hCG) using partial reduction and S-[14C]carboxymethylation has been reported earlier (Mise, T., and Bahl, O. P. (1980) J. Biol. Chem. 255, 8516-8522). Employing a similar approach, we have determined the locations of six disulfide bonds in hCG-beta.
T, Mise, O P, Bahl
openaire +3 more sources
Ovarian Sex Cord Stromal Tumor With Annular Tubules: A Rare Diagnosis in Young Women
ABSTRACT Ovarian sex cord‐stromal tumor with annular tubules (SCTAT) is a rare neoplasm with distinct clinicopathological features in its sporadic and syndromic forms, the latter commonly associated with Peutz‐Jeghers syndrome. Although imaging may suggest a sex cord‐stromal origin, definitive diagnosis relies on histopathological examination.
Prescillia Marques +3 more
wiley +1 more source
Tumor-associated antigen human chorionic gonadotropin beta contains numerous antigenic determinants recognized by in vitro-induced CD8+ and CD4+ T lymphocytes. [PDF]
The beta subunit of human chorionic gonadotropin (hCG beta) is markedly overexpressed by neoplastic cells of differing histological origin including those present in colon, breast, prostate and bladder tumors.
A. Scardino +11 more
core +2 more sources
P4‐ATPases as Phospholipid Flippases: From Membrane Dynamics to Human Disorders
ABSTRACT P4‐ATPases (P4 subfamily of P‐type ATPases) flippase complex includes an α‐subunit responsible for catalysis and a supporting β‐subunit, which consumes energy by catalyzing the hydrolysis of ATP, thereby facilitating the translocation of aminophospholipids from the outer to the inner leaflet of cellular membranes to maintain the asymmetric ...
Guangyi Chen, Yeming Yang, Xianjun Zhu
wiley +1 more source
Human chorionic gonadotropin (hCG) concentrations during the late first trimester are associated with fetal growth in a fetal sex-specific manner [PDF]
Human chorionic gonadotropin (hCG) is a pregnancy-specific hormone that regulates placental development. hCG concentrations vary widely throughout gestation and differ based on fetal sex.
Barjaktarovic, M. (Mirjana) +6 more
core +1 more source
The Concise Guide to PHARMACOLOGY 2025/26: G protein‐coupled receptors
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +206 more
wiley +1 more source
Chen-Yu Chen,1–3 Yuh-Ming Hwu,2 Chie-Pein Chen,2 Chia-Chen Chang41Department of Medicine, Mackay Medical College, New Taipei City, Taiwan; 2Department of Obstetrics and Gynecology, Mackay Memorial Hospital, Taipei, Taiwan; 3Mackay Junior College of
Chen CY, Hwu YM, Chen CP, Chang CC
doaj
Study objective To determine the prevalence of false negative point‐of‐care (POC) urine pregnancy tests among emergency department (ED) patients and among those with abdominal pain or vaginal bleeding.
Sarah Kleinschmidt +3 more
doaj +1 more source
GLE1 plays a direct role mRNA regulation, translation, and formation of cytosolic stress granules. GLE1 dysfunction has been associated with devastating diseases, including lethal congenital contracture syndrome 1(LCCS1), a rare disorder enriched in isolated populations.
Tomáš Zárybnický +22 more
wiley +1 more source

