Abortifacient Vaccine Technology: Overview, Hazards, and Christian Response [PDF]
Roberge, Lawrence F.
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Expression and prognostic value of HCGβ in digestive tract malignancies [PDF]
Louhimo, Johanna
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First trimester Down\u92s syndrome screening The role of biochemistry [PDF]
Ranta-Ylikulju, Jenni
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Human Chorionic Gonadotropin β-Subunit in Human Semen
Archives of Andrology, 1988The level of human seminal chorionic gonadotropin beta-subunit (hCG beta) was determined by radioimmunoassay (RIA). The mean hCG beta level in 34 normal men was 3.7 +/- 1.6 ng/ml, which was much higher than that in serum. The mean hCG beta level for 20 patients with mild oligozoospermia (20-39 x 10(6) sperm/ml) was 2.5 +/- 0.8 ng/ml, that for 34 ...
N Ito, S Saito, Y Kumamoto, T Kurohata
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Posttranslational modification of the carboxy-terminal region of the .beta. subunit of human chorionic gonadotropin [PDF]
The beta subunit of human chorionic gonadotropin (hCG) contains at its carboxy terminus an extension of 29 amino acids not found in the beta subunits of the other glycoprotein hormones. This region provides the sites of attachment of four serine-linked oligosaccharide chains.
Steven R. Lentz+3 more
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Immunological properties of the β-subunit of human chorionic gonadotropin
Biochemical and Biophysical Research Communications, 1976Abstract The β-subunit of human chorionic gonadotropin (hCG-β) has been modified to a varying degree by the cleavage of the disulfide bonds by reduction with dithioerythritol followed by S-carboxamidomethylation. The resulting derivatives of hCG-β show a preferential loss in their immunological cross-reactivity with human luteinizing hormone (hLH ...
R.D. Ghai, Om P. Bahl, M.R. Pandia
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Abstract Four different derivatives with varying proportions of dinitrophenyl (DNP) groups tagged covalently to β-subunit of HCG (DNP (1) -β-HCG, DNP (3.3) -β-HCG, DNP (6) -β-HCG and DNP (10) -β-HCG) have been prepared. Their immunogenicity as well as the reactivity of antibodies formed in mice, rabbit and rhesus monkey have been studied.
N. Shastri+3 more
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The Expression of the Human Chorionic Gonadotropin Beta Subunit Gene Depends on Negative Control
Cell Biochemistry and Function, 1996AbstractTranscription of the human chorionic gonadotropin (hCG) genes begins in the very early embryo stage and decreases or even disappears in nonplacental tissues. We have studied the regulation of hCG‐beta genes by cell fusion and by the reverse transcription‐polymerase chain reaction (RT‐PCR).
Yen-Hui Chen+2 more
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Fragmentation of the β-Subunit of Human Chorionic Gonadotropin Produced by Choriocarcinoma*
Endocrinology, 1988When human chorionic gonadotropin (hCG) was subjected to sodium dodecyl sulfate-polyacrylamide gel electrophoresis under reducing conditions with dithiothreitol (DTT), a smaller weight material (CTP'), in addition to the beta-subunit, could be detected by Western blot analysis using antiserum for hCG beta-carboxy-terminal peptide (CTP).
Taku Utsunomiya+5 more
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Location of major antigenic sites of the β-subunit of human chorionic gonadotropin
Biochemistry, 1978Purified beta subunit of human chorionic gonadotropin (hCG) was partially reduced with beta-mercaptoethanol, carboxymethylated, and digested with chymotrypsin. The peptides were isolated by high-voltage electrophoresis and paper chromatography. Five major disulfide-containing peptides were isolated, and their location in the parent molecule was ...
Glenn D. Braunstein, N. Swaminathan
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