Results 11 to 20 of about 578,337 (355)
Biomedicines, 2023 Cardiovascular diseases are a major cause of death globally, with no cure to date. Many interventions have been studied and suggested, of which epigenetics and chromatin remodeling have been the most promising.
Lindsay Kraus, Brianna Beavens
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The chromatin remodeler SPLAYED regulates specific stress signaling pathways. [PDF]
PLoS Pathogens, 2008 Organisms are continuously exposed to a myriad of environmental stresses. Central to an organism's survival is the ability to mount a robust transcriptional response to the imposed stress. An emerging mechanism of transcriptional control involves dynamic
Justin W Walley +6 more
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Knockdown of DOM/Tip60 Complex Subunits Impairs Male Meiosis of Drosophila melanogaster
Cells, 2023 ATP-dependent chromatin remodeling complexes are involved in nucleosome sliding and eviction and/or the incorporation of histone variants into chromatin to facilitate several cellular and biological processes, including DNA transcription, replication and
Yuri Prozzillo +5 more
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Sodium Valproate-Induced Chromatin Remodeling
Frontiers in Cell and Developmental Biology, 2021 Valproic acid/sodium valproate (VPA), a drug originally prescribed as an anticonvulsant, has been widely reported to act on epigenetic marks by inducing histone acetylation, affecting the DNA and histone methylation status, and altering the expression of
Maria Luiza S. Mello
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Cryo-EM structure of SWI/SNF chromatin remodeling complex with nucleosome
Nature, 2020 The chromatin-remodelling complex SWI/SNF is highly conserved and has critical roles in various cellular processes, including transcription and DNA-damage repair1,2.
Yan Han +3 more
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Chromatin remodelers in oligodendroglia [PDF]
Glia, 2020 AbstractOligodendrocytes, the myelinating cells in the vertebrate central nervous system, produce myelin sheaths to enable saltatory propagation of action potentials. The process of oligodendrocyte myelination entails a stepwise progression from precursor specification to differentiation, which is coordinated by a series of transcriptional and ...
Carlos Parras +3 more
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Biology, 2020 Myogenesis is the biological process by which skeletal muscle tissue forms. Regulation of myogenesis involves a variety of conventional, epigenetic, and epigenomic mechanisms that control chromatin remodeling, DNA methylation, histone modification, and ...
Teresita Padilla-Benavides +2 more
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Cancer Science, 2020 The SWI/SNF chromatin remodeling complex is composed of approximately 15 subunits, and approximately 20% of all cancers carry mutations in the genes encoding these subunits.
Mariko Sasaki, H. Ogiwara
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HGG Advances, 2023 Summary: GATA zinc finger domain containing 2A (GATAD2A) is a subunit of the nucleosome remodeling and deacetylase (NuRD) complex. NuRD is known to regulate gene expression during neural development and other processes.
Elizabeth A. Werren +18 more
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Cancer Medicine, 2023 Genetic information encoded by DNA is packaged in the nucleus using the chromatin structure. The accessibility of transcriptional elements in DNA is controlled by the dynamic structural changes of chromatin for the appropriate regulation of gene ...
Yasumichi Kuwahara +3 more
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