Results 11 to 20 of about 201,890 (354)

ATP-dependent chromatosome remodeling [PDF]

, 2008
Chromatin serves to package, protect and organize the complex eukaryotic genomes to assure their stable inheritance over many cell generations. At the same time, chromatin must be dynamic to allow continued use of DNA during a cell's lifetime.
Dimitrov S., Langst G., Loyola A., Ner S.S., Shogren-Knaak M., Varga-Weisz P.D., Wisniewski J.R.   +6 more
core   +1 more source

Chromatin remodelers in oligodendroglia [PDF]

Glia, 2020
AbstractOligodendrocytes, the myelinating cells in the vertebrate central nervous system, produce myelin sheaths to enable saltatory propagation of action potentials. The process of oligodendrocyte myelination entails a stepwise progression from precursor specification to differentiation, which is coordinated by a series of transcriptional and ...
Carlos Parras, Corentine Marie, Chuntao Zhao, Qing Richard Lu   +3 more
openaire   +3 more sources

Regulation of the Mammalian SWI/SNF Family of Chromatin Remodeling Enzymes by Phosphorylation during Myogenesis

Biology, 2020
Myogenesis is the biological process by which skeletal muscle tissue forms. Regulation of myogenesis involves a variety of conventional, epigenetic, and epigenomic mechanisms that control chromatin remodeling, DNA methylation, histone modification, and ...
Teresita Padilla-Benavides, Pablo Reyes-Gutierrez, Anthony N. Imbalzano   +2 more
doaj   +1 more source

De novo variants in GATAD2A in individuals with a neurodevelopmental disorder: GATAD2A-related neurodevelopmental disorder

HGG Advances, 2023
Summary: GATA zinc finger domain containing 2A (GATAD2A) is a subunit of the nucleosome remodeling and deacetylase (NuRD) complex. NuRD is known to regulate gene expression during neural development and other processes.
Elizabeth A. Werren, Alba Guxholli, Natasha Jones, Matias Wagner, Iris Hannibal, Jorge L. Granadillo, Amanda V. Tyndall, Amanda Moccia, Ryan Kuehl, Kristin M. Levandoski, Debra L. Day-Salvatore, Marsha Wheeler, Jessica X. Chong, Michael J. Bamshad, A. Micheil Innes, Tyler Mark Pierson, Joel P. Mackay, Stephanie L. Bielas, Donna M. Martin   +18 more
doaj   +1 more source

DNA-encoded nucleosome occupancy is associated with transcription levels in the human malaria parasite Plasmodium falciparum. [PDF]

, 2014
BackgroundIn eukaryotic organisms, packaging of DNA into nucleosomes controls gene expression by regulating access of the promoter to transcription factors.
Bunnik, Evelien M, Gill, Sarjeet S, Le Roch, Karine G, Lonardi, Stefano, Polishko, Anton, Ponts, Nadia, Prudhomme, Jacques   +6 more
core   +3 more sources

Recent insights into the SWI/SNF complex and the molecular mechanism of hSNF5 deficiency in rhabdoid tumors

Cancer Medicine, 2023
Genetic information encoded by DNA is packaged in the nucleus using the chromatin structure. The accessibility of transcriptional elements in DNA is controlled by the dynamic structural changes of chromatin for the appropriate regulation of gene ...
Yasumichi Kuwahara, Tomoko Iehara, Akifumi Matsumoto, Tsukasa Okuda   +3 more
doaj   +1 more source

Lysosome-mediated processing of chromatin in senescence [PDF]

, 2013
Cellular senescence is a stable proliferation arrest, a potent tumor suppressor mechanism, and a likely contributor to tissue aging. Cellular senescence involves extensive cellular remodeling, including of chromatin structure. Autophagy and lysosomes are
Adams, Adams-Cioaba, Andre Ivanov, Barnhill, Barradas, Bodnar, Braig, Bridger, Butin-Israeli, Cao, Chen, Chen, Coffinier, Collado, Cosme-Blanco, Dang, David M. Nelson, De Cecco, De Cecco, De Vos, Demidenko, Di Micco, Duncan, Feldser, Feser, Fraga, Freund, Funayama, Glatz, Goldman, Graeme Hewitt, Gray-Schopfer, Gray-Schopfer, Greer, Hayflick, Hong Wu, Houben, Howard, Hunt, Ichijima, Iglesias-Bartolome, Imai, Indrani Manoharan, Ishidoh, Jeff Pawlikowski, Joao F. Passos, John van Tuyn, Kanfi, Kang, Kennedy, Klionsky, Kreiling, Krizhanovsky, Krtolica, Kuilman, Lamark, Laszlo, Lee, Maures, McManus, Michaloglou, Michishita, Narita, Narita, Narita, Omholt, O’Sullivan, Pankiv, Parisha P. Shah, Passos, Peleg, Peter D. Adams, Pollock, Pospelova, Ruhoy, Sagiv, Santos-Rosa, Scaffidi, Serrano, Shelley L. Berger, Shimi, Shimi, Siebold, Smolle, Smolle, Soutoglou, Suram, Taranjit Singh Rai, Tran, Vargas, Vergnes, Viktor I. Korolchuk, Villeponteau, Wang, Wood, Xue, Yang, Young, Zhang, Zhang, Ziegler-Birling   +100 more
core   +2 more sources

Immunity onset alters plant chromatin and utilizes EDA16 to regulate oxidative homeostasis.

PLoS Pathogens, 2021
Perception of microbes by plants leads to dynamic reprogramming of the transcriptome, which is essential for plant health. The appropriate amplitude of this transcriptional response can be regulated at multiple levels, including chromatin.
Alonso J Pardal, Sophie J M Piquerez, Ana Dominguez-Ferreras, Lucas Frungillo, Emmanouil Mastorakis, Emma Reilly, David Latrasse, Lorenzo Concia, Selena Gimenez-Ibanez, Steven H Spoel, Moussa Benhamed, Vardis Ntoukakis   +11 more
doaj   +1 more source

Snf2 family ATPases and DExx box helicases:differences and unifying concepts from high-resolution crystal structures [PDF]

, 2006
Proteins with sequence similarity to the yeast Snf2 protein form a large family of ATPases that act to alter the structure of a diverse range of DNA–protein structures including chromatin. Snf2 family enzymes are related in sequence to DExx box helicases,
Aasland, Ahne, Akhtar, Andrew Flaus, Asturias, Auble, Auble, Auble, Bazett-Jones, Becker, Beerens, Bouazoune, Boyer, Boyer, Briggs, Caruthers, Corona, Cote, Dasgupta, Davis, Deaconescu, Dhalluin, Dumont, Durr, Eisen, Fan, Fitzgerald, Flaus, Flaus, Goldmark, Gorbalenya, Grune, Harald Dürr, Havas, Hishida, Ito, Jaskelioff, Kagalwala, Karl-Peter Hopfner, Kawaoka, Kim, Laurent, Laurent, Levin, Levin, Lia, Mahdi, Mannhaupt, Mizuguchi, Morillon, Myong, Peterson, Petukhova, Petukhova, Phelan, Pray-Grant, Quinn, Richmond, Ristic, Saha, Saha, Schild, Sengoku, Serebrov, Shen, Shinohara, Simic, Sims, Singleton, Singleton, Singleton, Smith, Soultanas, Sprouse, Stanley, Studitsky, Subramanya, Sukhodolets, Svejstrup, Swagemakers, Tai, Thoma, Tom Owen-Hughes, Tran, Tsukiyama, van den Boom, van Gool, Van Komen, Velankar, Wang, Whitehouse, Woudstra, Yu, Yu, Zhang, Zofall   +95 more
core   +4 more sources

ATP-dependent chromatin assembly is functionally distinct from chromatin remodeling

eLife, 2013
Chromatin assembly involves the combined action of ATP-dependent motor proteins and histone chaperones. Because motor proteins in chromatin assembly also function as chromatin remodeling factors, we investigated the relationship between ATP-driven ...
Sharon E Torigoe, Ashok Patel, Mai T Khuong, Gregory D Bowman, James T Kadonaga   +4 more
doaj   +1 more source