Results 31 to 40 of about 124,418 (260)

BRG1 HSA domain interactions with BCL7 proteins are critical for remodeling and gene expression

open access: yesLife Science Alliance, 2023
Interactions between the BRG1 HSA domain and the B-cell CLL/lymphoma 7 proteins facilitate BRG1-mediated chromatin remodeling and induce changes in the gene expression of essential biological pathways.
Nicholas Dietrich   +3 more
doaj   +1 more source

De novo variants in GATAD2A in individuals with a neurodevelopmental disorder: GATAD2A-related neurodevelopmental disorder

open access: yesHGG Advances, 2023
Summary: GATA zinc finger domain containing 2A (GATAD2A) is a subunit of the nucleosome remodeling and deacetylase (NuRD) complex. NuRD is known to regulate gene expression during neural development and other processes.
Elizabeth A. Werren   +18 more
doaj   +1 more source

Remodeling chromatin for senescence [PDF]

open access: yesAging Cell, 2007
SummaryCellular senescence is an irreversible proliferation arrest that contributes to tumor suppression and, perhaps, tissue aging. Senescence is frequently accompanied by an increase in nuclear heterochromatin, which is thought to promote proliferation arrest. In this issue, Medrano and co‐workers describe new insights into the protein complexes that
openaire   +2 more sources

Immunity onset alters plant chromatin and utilizes EDA16 to regulate oxidative homeostasis.

open access: yesPLoS Pathogens, 2021
Perception of microbes by plants leads to dynamic reprogramming of the transcriptome, which is essential for plant health. The appropriate amplitude of this transcriptional response can be regulated at multiple levels, including chromatin.
Alonso J Pardal   +11 more
doaj   +1 more source

GBAF, a small BAF sub-complex with big implications: a systematic review

open access: yesEpigenetics & Chromatin, 2020
ATP-dependent chromatin remodeling by histone-modifying enzymes and chromatin remodeling complexes is crucial for maintaining chromatin organization and facilitating gene transcription.
Sarah M. Innis, Birgit Cabot
doaj   +1 more source

Remodeling is at the heart of chromatin [PDF]

open access: yesEpigenetics, 2011
Chromatin modifications are integral elements of chromosome structure and its function and the vasculature depends on tissue-specific genome regulation for its development. A general concept for the de-regulation of chromatin modifications in cardiac and vascular disease is also emerging.
openaire   +2 more sources

The role of aTp-dependent chromatin remodeling factors in chromatin assembly in vivo

open access: yesВавиловский журнал генетики и селекции, 2019
Chromatin assembly is a fundamental process essential for chromosome duplication subsequent to DNA replication. In addition, histone removal and incorporation take place constantly throughout the cell cycle in the course of DNA-utilizing processes, such ...
Iu. A. Il’ina, A. Yu. Konev
doaj   +1 more source

CHRAC/ACF contribute to the repressive ground state of chromatin

open access: yesLife Science Alliance, 2018
Chromatin accessibility complex/ATP-utilizing chromatin assembly and remodeling factor help to establish basal transcriptional repression, conceivably through improving the regular spacing of nucleosomes in euchromatin. The chromatin remodeling complexes
Alessandro Scacchetti   +8 more
doaj   +1 more source

Remodeling Chromatin in an ARID Environment [PDF]

open access: yesThe Plant Cell, 2020
The control of gene expression is of fundamental importance for cellular life. In Eukaryotes, linear DNA is wrapped around nucleosomes that constitute a physical barrier to active transcription. Chromatin remodeling complexes modulate the composition, stability, and positioning of nucleosomes,
openaire   +2 more sources

Dynamic remodeling of individual nucleosomes across a eukaryotic genome in response to transcriptional perturbation. [PDF]

open access: yesPLoS Biology, 2008
The eukaryotic genome is packaged as chromatin with nucleosomes comprising its basic structural unit, but the detailed structure of chromatin and its dynamic remodeling in terms of individual nucleosome positions has not been completely defined ...
Sushma Shivaswamy   +5 more
doaj   +1 more source

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