Results 31 to 40 of about 199,504 (302)

The BAH domain of Rsc2 is a histone H3 binding domain [PDF]

, 2013
Bromo-adjacent homology (BAH) domains are commonly found in chromatin-associated proteins and fall into two classes; Remodels the Structure of Chromatin (RSC)-like or Sir3-like. Although Sir3-like BAH domains bind nucleosomes, the binding partners of RSC-
Adams, Angus-Hill, Anna L. Chambers, Antony W. Oliver, Armache, Badis, Bamford, Bochar, Burrows, Cairns, Cairns, Callebaut, CCP4, Chambers, Chen, Corpet, Davis, DeMase, Desai, Downs, Duncker, Emsley, Ericsson, Faucher, Foster, Gartenberg, Gartenberg, Goodwin, Hickman, Hsu, Huang, Jessica A. Downs, Jones, Kabsch, Kasten, Kent, Kuo, Lacoste, Langst, Laurence H. Pearl, Lee, Leslie, Livingstone, Longtine, McCoy, Mohrmann, Muller, Ng, Noguchi, Norris, Norris, Oliver, Onishi, Park, Peng, Ralhan, Shim, Strahl-Bolsinger, Tanny, Varela, Weissman, Xia   +61 more
core   +1 more source

PTEN in Chromatin Remodeling [PDF]

Cold Spring Harbor Perspectives in Medicine, 2019
The tumor suppressor phosphatase and tension homolog (PTEN) is frequently mutated in human cancers, and it functions in multiple ways to safeguard cells from tumorigenesis. In the cytoplasm, PTEN antagonizes the PI3K/AKT pathway and suppresses cellular proliferation and survival.
Jingyi, Yang, Yuxin, Yin
openaire   +2 more sources

Genome-wide analysis of interactions between ATP-dependent chromatin remodeling and histone modifications

BMC Genomics, 2009
Background ATP-dependent chromatin remodeling and the covalent modification of histones play central roles in determining chromatin structure and function.
Wang Jiang, Feng Jihua, Xiang Qian, Dai Xianhua, Dai Zhiming, Deng Yangyang, He Caisheng   +6 more
doaj   +1 more source

Dynamic changes in ANGUSTIFOLIA3 complex composition reveal a growth regulatory mechanism in the maize leaf [PDF]

, 2015
Most molecular processes during plant development occur with a particular spatio-temporal specificity. Thus far, it has remained technically challenging to capture dynamic protein-protein interactions within a growing organ, where the interplay between ...
Aesaert, Stijn, Candaele, Jasper, De Block, Jolien, De Jaeger, Geert, Demuynck, Kirin, Eeckhout, Dominique, Gevaert, Kris, Goormachtig, Sofie, Inzé, Dirk, Muszynski, Michael, Nelissen, Hilde, Persiau, Geert, Van Bel, Michiel, Van Leene, Jelle, Van Lijsebettens, Maria, Vandepoele, Klaas, Vervoort, Marieke, Walton, Alan   +17 more
core   +2 more sources

AIP1 is a novel Agenet/Tudor domain protein from Arabidopsis that interacts with regulators of DNA replication, transcription and chromatin remodeling [PDF]

, 2015
Background: DNA replication and transcription are dynamic processes regulating plant development that are dependent on the chromatin accessibility. Proteins belonging to the Agenet/Tudor domain family are known as histone modification "readers" and ...
Barroso-Neto, Ito Liberato, Brasil, Juliana Nogueira, Cabral, Luiz Mors, Eloy, Nubia Barbosa, Ferreira, Paulo CG, Gonzalez Sanchez, Nathalie, Hemerly, Adriana S, Inzé, Dirk, Perdigão Grangeiro, Leticia P, Primo, Luiza MF   +9 more
core   +3 more sources

Engineered Chromatin Remodeling Proteins for Precise Nucleosome Positioning

Cell Reports, 2019
Summary: Regulation of chromatin structure is essential for controlling access of DNA to factors that require association with specific DNA sequences. Here we describe the development and validation of engineered chromatin remodeling proteins (E-ChRPs ...
Drake A. Donovan, Johnathan G. Crandall, Orion G.B. Banks, Zena D. Jensvold, Vi Truong, Devin Dinwiddie, Laura E. McKnight, Jeffrey N. McKnight   +7 more
doaj   +1 more source

Differential chromatin accessibility in peripheral blood mononuclear cells underlies COVID-19 disease severity prior to seroconversion

Scientific Reports, 2022
SARS-CoV-2 infection triggers profound and variable immune responses in human hosts. Chromatin remodeling has been observed in individuals severely ill or convalescing with COVID-19, but chromatin remodeling early in disease prior to anti-spike protein ...
Nicholas S. Giroux, Shengli Ding, Micah T. McClain, Thomas W. Burke, Elizabeth Petzold, Hong A. Chung, Grecia O. Rivera, Ergang Wang, Rui Xi, Shree Bose, Tomer Rotstein, Bradly P. Nicholson, Tianyi Chen, Ricardo Henao, Gregory D. Sempowski, Thomas N. Denny, Maria Iglesias De Ussel, Lisa L. Satterwhite, Emily R. Ko, Geoffrey S. Ginsburg, Bryan D. Kraft, Ephraim L. Tsalik, Xiling Shen, Christopher W. Woods   +23 more
doaj   +1 more source

Basis of specificity for a conserved and promiscuous chromatin remodeling protein

eLife, 2021
Eukaryotic genomes are organized dynamically through the repositioning of nucleosomes. Isw2 is an enzyme that has been previously defined as a genome-wide, nonspecific nucleosome spacing factor.
Drake A Donovan, Johnathan G Crandall, Vi N Truong, Abigail L Vaaler, Thomas B Bailey, Devin Dinwiddie, Orion GB Banks, Laura E McKnight, Jeffrey N McKnight   +8 more
doaj   +1 more source

A Double-Edged Role for SIRT7 in Cancer: Can Anti-Cancer Immunity Tip the Balance?

Pharmaceuticals
Background/Objectives: Sirtuin 7 (SIRT7), a nuclear NAD+-dependent deacylase, plays multifaceted and sometimes opposing roles in tumorigenesis. By preserving chromatin architecture and genome integrity, SIRT7 protects against malignant transformation ...
Shahriar Tarighi, Zifan Ning, Andrés Gámez-García, Alejandro Vaquero, Thomas Braun, Alessandro Ianni   +5 more
doaj   +1 more source

BPTF promotes tumor growth and predicts poor prognosis in lung adenocarcinomas. [PDF]

, 2015
BPTF, a subunit of NURF, is well known to be involved in the development of eukaryotic cell, but little is known about its roles in cancers, especially in non-small-cell lung cancer (NSCLC).
Dai, Meng, Deng, Wenbin, Guo, Wei, Huang, Wenlin, Li, Zhenglin, Lu, Jian-Jun, Qin, Yu, Sun, Wei, Sun, Xiuna, Tang, Ranran, Tang, Zhipeng, Wang, Qimin, Wu, Taihua, Xiao, Yao, Yu, Wendan   +14 more
core   +3 more sources