Results 31 to 40 of about 422,700 (297)

Chromatin remodeling enzyme Brg1 is required for mouse lens fiber cell terminal differentiation and its denucleation [PDF]

, 2010
Background: Brahma-related gene 1 (Brg1, also known as Smarca4 and Snf2 beta) encodes an adenosine-5'-triphosphate (ATP)-dependent catalytical subunit of the (switch/sucrose nonfermentable) (SWI/SNF) chromatin remodeling complexes.
He, Shuying, Metzger, Daniel, Wolf Louise, Bharesh K Chauhan, Chambon, Pierre, Ruth Ashery-Padan, Nakai, Akira, Zavadil, Jiri, Cveklova Kveta, Daniel Metzger, Ernst R Tamm, Chauhan Bharesh K, Metzger Daniel, Melinda K Pirity, Wang Wei-Lin, Chauhan, Bharesh K., Pierre Chambon, Cveklova, Kveta, Cvekl Ales, Akira Nakai, Ales Cvekl, Pirity Melinda K, Wolf, Louise, Tamm, Ernst R., Ashery-Padan, Ruth, Cvekl, Ales, Chambon Pierre, Wang, Wei-Lin, Wei-Lin Wang, Ashery-Padan Ruth, Nakai Akira, He Shuying, Shuying He, Kveta Cveklova, Zavadil Jiri, Louise Wolf, Tamm Ernst R, Jiri Zavadil, Pirity, Melinda K.   +38 more
core   +1 more source

Regulation of the Mammalian SWI/SNF Family of Chromatin Remodeling Enzymes by Phosphorylation during Myogenesis

Biology, 2020
Myogenesis is the biological process by which skeletal muscle tissue forms. Regulation of myogenesis involves a variety of conventional, epigenetic, and epigenomic mechanisms that control chromatin remodeling, DNA methylation, histone modification, and ...
Teresita Padilla-Benavides, Pablo Reyes-Gutierrez, Anthony N. Imbalzano   +2 more
doaj   +1 more source

Dynamic chromatin: concerted nucleosome remodelling and acetylation [PDF]

, 2005
The flexibility of chromatin that enables translation of environmental cues into changes in genome utilisation, relies on a battery of enzymes able to modulate chromatin structure in a highly targeted and regulated manner.
Eberharter, Anton, Becker, Peter, Ferreira, Roger   +2 more
core   +1 more source

ATP-dependent chromatin assembly is functionally distinct from chromatin remodeling

eLife, 2013
Chromatin assembly involves the combined action of ATP-dependent motor proteins and histone chaperones. Because motor proteins in chromatin assembly also function as chromatin remodeling factors, we investigated the relationship between ATP-driven ...
Sharon E Torigoe, Ashok Patel, Mai T Khuong, Gregory D Bowman, James T Kadonaga   +4 more
doaj   +1 more source

Interaction of HP1 and Brg1/Brm with the Globular Domain of Histone H3 Is Required for HP1-Mediated Repression [PDF]

, 2009
The heterochromatin-enriched HP1 proteins play a critical role in regulation of transcription. These proteins contain two related domains known as the chromo- and the chromoshadow-domain.
Fan Hua-Ying, Kingston Robert E., Violaine Saint-André, Christian Muchardt, Saint-Andre, Violaine, Imhof Axel, Batsché Eric, Jang Suk Min, Kingston, Robert E., Saliha Azebi, Robert E Kingston, Axel Imhof, Jang, Suk Min, Eskeland, Ragnhild, Eskeland Ragnhild, Muchardt Christian, Eric Batsché, Azebi Saliha, Fan, Hua-Ying, Muchardt, Christian, Batsche, Eric, Hua-Ying Fan, Marc Lavigne, Ragnhild Eskeland, Saint-André Violaine, Imhof, Axel, Lavigne, Marc, Azebi, Saliha, Suk Min Jang, Lavigne Marc   +29 more
core   +2 more sources

Remodeling chromatin for senescence [PDF]

Aging Cell, 2007
SummaryCellular senescence is an irreversible proliferation arrest that contributes to tumor suppression and, perhaps, tissue aging. Senescence is frequently accompanied by an increase in nuclear heterochromatin, which is thought to promote proliferation arrest. In this issue, Medrano and co‐workers describe new insights into the protein complexes that
openaire   +2 more sources

Theory of active chromatin remodeling [PDF]

Physical Review Letters, 2019
Nucleosome positioning controls the accessible regions of chromatin and plays essential roles in DNA-templated processes. ATP driven remodeling enzymes are known to be crucial for its establishment in vivo , but their non-equilibrium nature has hindered the development of a unified theoretical ...
Jiang, Zhongling, Zhang, Bin
openaire   +4 more sources

Remodeling Chromatin in an ARID Environment [PDF]

The Plant Cell, 2020
The control of gene expression is of fundamental importance for cellular life. In Eukaryotes, linear DNA is wrapped around nucleosomes that constitute a physical barrier to active transcription. Chromatin remodeling complexes modulate the composition, stability, and positioning of nucleosomes,
openaire   +2 more sources

Proteomic interrogation of human chromatin. [PDF]

, 2011
Chromatin proteins provide a scaffold for DNA packaging and a basis for epigenetic regulation and genomic maintenance. Despite understanding its functional roles, mapping the chromatin proteome (i.e. the "Chromatome") is still a continuing process. Here,
LeRoy, Gary, Christodoulos A Floudas, Floudas, Christodoulos A., Barry M Zee, Garcia, Benjamin A., Richard C Baliban, Baliban, Richard C., Sandra B Hake, Torrente, Mariana P., Zee, Barry M., Hake, Sandra B., Christodoulos A. Floudas, Barry M. Zee, Nicolas L. Young, Mariana P. Torrente, Gary LeRoy, Richard C. Baliban, Sandra B. Hake, Benjamin A. Garcia, Nicolas L Young, Benjamin A Garcia, Young, Nicolas L., Mariana P Torrente   +22 more
core   +2 more sources

Recent insights into the SWI/SNF complex and the molecular mechanism of hSNF5 deficiency in rhabdoid tumors

Cancer Medicine, 2023
Genetic information encoded by DNA is packaged in the nucleus using the chromatin structure. The accessibility of transcriptional elements in DNA is controlled by the dynamic structural changes of chromatin for the appropriate regulation of gene ...
Yasumichi Kuwahara, Tomoko Iehara, Akifumi Matsumoto, Tsukasa Okuda   +3 more
doaj   +1 more source