Results 51 to 60 of about 680,917 (346)

De novo variants in GATAD2A in individuals with a neurodevelopmental disorder: GATAD2A-related neurodevelopmental disorder

open access: yesHGG Advances, 2023
Summary: GATA zinc finger domain containing 2A (GATAD2A) is a subunit of the nucleosome remodeling and deacetylase (NuRD) complex. NuRD is known to regulate gene expression during neural development and other processes.
Elizabeth A. Werren   +18 more
doaj   +1 more source

Theory of active chromatin remodeling [PDF]

open access: yesPhysical Review Letters, 2019
Nucleosome positioning controls the accessible regions of chromatin and plays essential roles in DNA-templated processes. ATP driven remodeling enzymes are known to be crucial for its establishment in vivo , but their non-equilibrium nature has hindered the development of a unified theoretical ...
Jiang, Zhongling, Zhang, Bin
openaire   +3 more sources

The DNA-binding domain of the Chd1 chromatin-remodelling enzyme contains SANT and SLIDE domains [PDF]

open access: yes, 2011
The ATP-dependent chromatin-remodelling enzyme Chd1 is a 168-kDa protein consisting of a double chromodomain, Snf2-related ATPase domain, and a C-terminal DNA-binding domain.
Daniel P Ryan   +9 more
core   +1 more source

Immunity onset alters plant chromatin and utilizes EDA16 to regulate oxidative homeostasis.

open access: yesPLoS Pathogens, 2021
Perception of microbes by plants leads to dynamic reprogramming of the transcriptome, which is essential for plant health. The appropriate amplitude of this transcriptional response can be regulated at multiple levels, including chromatin.
Alonso J Pardal   +11 more
doaj   +1 more source

SWI/SNF Complex Prevents Lineage Reversion and Induces Temporal Patterning in Neural Stem Cells [PDF]

open access: yes, 2014
Members of the SWI/SNF chromatin-remodeling complex are among the most frequently mutated genes in human cancer, but how they suppress tumorigenesis is currently unclear.
Knoblich, Juergen A.   +7 more
core   +1 more source

Histone modifications influence the action of Snf2 family remodelling enzymes by different mechanisms [PDF]

open access: yes, 2007
Alteration of chromatin structure by chromatin modifying and remodelling activities is a key stage in the regulation of many nuclear processes. These activities are frequently interlinked, and many chromatin remodelling enzymes contain motifs that ...
Owen-Hughes, Tom; id_orcid   +3 more
core   +1 more source

The role of aTp-dependent chromatin remodeling factors in chromatin assembly in vivo

open access: yesВавиловский журнал генетики и селекции, 2019
Chromatin assembly is a fundamental process essential for chromosome duplication subsequent to DNA replication. In addition, histone removal and incorporation take place constantly throughout the cell cycle in the course of DNA-utilizing processes, such ...
Iu. A. Il’ina, A. Yu. Konev
doaj   +1 more source

GBAF, a small BAF sub-complex with big implications: a systematic review

open access: yesEpigenetics & Chromatin, 2020
ATP-dependent chromatin remodeling by histone-modifying enzymes and chromatin remodeling complexes is crucial for maintaining chromatin organization and facilitating gene transcription.
Sarah M. Innis, Birgit Cabot
doaj   +1 more source

Remodeling Chromatin in an ARID Environment [PDF]

open access: yesThe Plant Cell, 2020
The control of gene expression is of fundamental importance for cellular life. In Eukaryotes, linear DNA is wrapped around nucleosomes that constitute a physical barrier to active transcription. Chromatin remodeling complexes modulate the composition, stability, and positioning of nucleosomes,
openaire   +2 more sources

CHRAC/ACF contribute to the repressive ground state of chromatin

open access: yesLife Science Alliance, 2018
Chromatin accessibility complex/ATP-utilizing chromatin assembly and remodeling factor help to establish basal transcriptional repression, conceivably through improving the regular spacing of nucleosomes in euchromatin. The chromatin remodeling complexes
Alessandro Scacchetti   +8 more
doaj   +1 more source

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