Results 11 to 20 of about 199,504 (302)

Chromatin remodeling in oligodendrogenesis

open access: yesВавиловский журнал генетики и селекции, 2021
Oligodendrocytes are one type of glial cells responsible for myelination and providing trophic support for axons in the central nervous system of vertebrates.
E. V. Antontseva, N. P. Bondar
doaj   +4 more sources

Chromatin remodelers in oligodendroglia [PDF]

open access: yesGlia, 2020
AbstractOligodendrocytes, the myelinating cells in the vertebrate central nervous system, produce myelin sheaths to enable saltatory propagation of action potentials. The process of oligodendrocyte myelination entails a stepwise progression from precursor specification to differentiation, which is coordinated by a series of transcriptional and ...
Carlos Parras   +3 more
openaire   +3 more sources

ATP-dependent chromatosome remodeling [PDF]

open access: yes, 2008
Chromatin serves to package, protect and organize the complex eukaryotic genomes to assure their stable inheritance over many cell generations. At the same time, chromatin must be dynamic to allow continued use of DNA during a cell's lifetime.
Dimitrov S.   +6 more
core   +1 more source

Lysosome-mediated processing of chromatin in senescence [PDF]

open access: yes, 2013
Cellular senescence is a stable proliferation arrest, a potent tumor suppressor mechanism, and a likely contributor to tissue aging. Cellular senescence involves extensive cellular remodeling, including of chromatin structure. Autophagy and lysosomes are
Adams   +100 more
core   +2 more sources

Regulation of the Mammalian SWI/SNF Family of Chromatin Remodeling Enzymes by Phosphorylation during Myogenesis

open access: yesBiology, 2020
Myogenesis is the biological process by which skeletal muscle tissue forms. Regulation of myogenesis involves a variety of conventional, epigenetic, and epigenomic mechanisms that control chromatin remodeling, DNA methylation, histone modification, and ...
Teresita Padilla-Benavides   +2 more
doaj   +1 more source

DNA-encoded nucleosome occupancy is associated with transcription levels in the human malaria parasite Plasmodium falciparum. [PDF]

open access: yes, 2014
BackgroundIn eukaryotic organisms, packaging of DNA into nucleosomes controls gene expression by regulating access of the promoter to transcription factors.
Bunnik, Evelien M   +6 more
core   +3 more sources

ATP-dependent chromatin assembly is functionally distinct from chromatin remodeling

open access: yeseLife, 2013
Chromatin assembly involves the combined action of ATP-dependent motor proteins and histone chaperones. Because motor proteins in chromatin assembly also function as chromatin remodeling factors, we investigated the relationship between ATP-driven ...
Sharon E Torigoe   +4 more
doaj   +1 more source

Identification of H3K4me1-associated proteins at mammalian enhancers. [PDF]

open access: yes, 2017
Enhancers act to regulate cell-type-specific gene expression by facilitating the transcription of target genes. In mammalian cells, active or primed enhancers are commonly marked by monomethylation of histone H3 at lysine 4 (H3K4me1) in a cell-type ...
Albuquerque, Claudio P   +13 more
core   +2 more sources

Recent insights into the SWI/SNF complex and the molecular mechanism of hSNF5 deficiency in rhabdoid tumors

open access: yesCancer Medicine, 2023
Genetic information encoded by DNA is packaged in the nucleus using the chromatin structure. The accessibility of transcriptional elements in DNA is controlled by the dynamic structural changes of chromatin for the appropriate regulation of gene ...
Yasumichi Kuwahara   +3 more
doaj   +1 more source

BRG1 HSA domain interactions with BCL7 proteins are critical for remodeling and gene expression

open access: yesLife Science Alliance, 2023
Interactions between the BRG1 HSA domain and the B-cell CLL/lymphoma 7 proteins facilitate BRG1-mediated chromatin remodeling and induce changes in the gene expression of essential biological pathways.
Nicholas Dietrich   +3 more
doaj   +1 more source

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