Results 21 to 30 of about 680,917 (346)
Dynamic remodeling of individual nucleosomes across a eukaryotic genome in response to transcriptional perturbation. [PDF]
PLoS Biology, 2008 The eukaryotic genome is packaged as chromatin with nucleosomes comprising its basic structural unit, but the detailed structure of chromatin and its dynamic remodeling in terms of individual nucleosome positions has not been completely defined ...
Sushma Shivaswamy +5 more
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Cell Reports, 2016 During DNA replication, chromatin must be disassembled and faithfully reassembled on newly synthesized genomes. The mechanisms that govern the assembly of chromatin structures following DNA replication are poorly understood.
Tejas Yadav, Iestyn Whitehouse
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Chromatin remodeling complexes: architects influencing breast cancer progression [PDF]
Frontiers in Cell and Developmental BiologyAs one of the most common types of cancer, breast cancer strongly contributes to the increase in morbidity and mortality worldwide. Alterations in the genetic and epigenetic landscape contribute to the complexity and heterogeneity of the disease, making ...
Octavianus Giovani +3 more
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Mechanisms of ATP-Dependent Chromatin Remodeling Motors [PDF]
Annual Review of Biophysics, 2016 Chromatin remodeling motors play essential roles in all DNA-based processes. These motors catalyze diverse outcomes ranging from sliding the smallest units of chromatin, known as nucleosomes, to completely disassembling chromatin.
Coral Y. Zhou +3 more
semanticscholar +2 more sources
Chromatin remodelers in oligodendroglia [PDF]
Glia, 2020 AbstractOligodendrocytes, the myelinating cells in the vertebrate central nervous system, produce myelin sheaths to enable saltatory propagation of action potentials. The process of oligodendrocyte myelination entails a stepwise progression from precursor specification to differentiation, which is coordinated by a series of transcriptional and ...
Carlos Parras +3 more
openaire +3 more sources
Structure and Function of ATP-dependent Chromatin Remodeling Complexes
Journal of Molecular Biology, 2021 Chromatin remodelers act to regulate multiple cellular processes, such as transcription and DNA repair, by controlling access to genomic DNA. Four families of chromatin remodelers have been identified in yeast, each with non-redundant roles within the ...
Alexis A Reyes, R. Marcum, Yuan He
semanticscholar +1 more source
Frontiers in Cellular and Infection Microbiology, 2022 Intracellular pathogens manipulate the host cell for their own survival by contributing to modifications of host epigenome, and thus, altering expression of genes involved in the pathogenesis.
Harsimran Kaur Brar +5 more
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Targeting Chromatin-Remodeling Factors in Cancer Cells: Promising Molecules in Cancer Therapy
International Journal of Molecular Sciences, 2022 ATP-dependent chromatin-remodeling complexes can reorganize and remodel chromatin and thereby act as important regulator in various cellular processes.
Fang-Lin Zhang, Da-Qiang Li
semanticscholar +1 more source
Biomedicines, 2023 Cardiovascular diseases are a major cause of death globally, with no cure to date. Many interventions have been studied and suggested, of which epigenetics and chromatin remodeling have been the most promising.
Lindsay Kraus, Brianna Beavens
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The chromatin remodeler SPLAYED regulates specific stress signaling pathways. [PDF]
PLoS Pathogens, 2008 Organisms are continuously exposed to a myriad of environmental stresses. Central to an organism's survival is the ability to mount a robust transcriptional response to the imposed stress. An emerging mechanism of transcriptional control involves dynamic
Justin W Walley +6 more
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