Results 21 to 30 of about 578,337 (355)

Immunity onset alters plant chromatin and utilizes EDA16 to regulate oxidative homeostasis.

open access: yesPLoS Pathogens, 2021
Perception of microbes by plants leads to dynamic reprogramming of the transcriptome, which is essential for plant health. The appropriate amplitude of this transcriptional response can be regulated at multiple levels, including chromatin.
Alonso J Pardal   +11 more
doaj   +1 more source

Targeting of the SWI/SNF chromatin remodeling complex in cancer therapy

open access: yesУспехи молекулярной онкологии, 2023
Chromatin remodeling is the one of the main epigenetic ways of gene expression regulation both in normal cells and in oncological diseases. Genes encoding protein subunits of SWI/ SNF remodeling complexes often mutate and/or change their expression in ...
M. V. Nemtsova, I. V. Bure
doaj   +1 more source

ATP-dependent chromatin assembly is functionally distinct from chromatin remodeling

open access: yeseLife, 2013
Chromatin assembly involves the combined action of ATP-dependent motor proteins and histone chaperones. Because motor proteins in chromatin assembly also function as chromatin remodeling factors, we investigated the relationship between ATP-driven ...
Sharon E Torigoe   +4 more
doaj   +1 more source

GBAF, a small BAF sub-complex with big implications: a systematic review

open access: yesEpigenetics & Chromatin, 2020
ATP-dependent chromatin remodeling by histone-modifying enzymes and chromatin remodeling complexes is crucial for maintaining chromatin organization and facilitating gene transcription.
Sarah M. Innis, Birgit Cabot
doaj   +1 more source

The role of aTp-dependent chromatin remodeling factors in chromatin assembly in vivo

open access: yesВавиловский журнал генетики и селекции, 2019
Chromatin assembly is a fundamental process essential for chromosome duplication subsequent to DNA replication. In addition, histone removal and incorporation take place constantly throughout the cell cycle in the course of DNA-utilizing processes, such ...
Iu. A. Il’ina, A. Yu. Konev
doaj   +1 more source

Dynamic remodeling of individual nucleosomes across a eukaryotic genome in response to transcriptional perturbation. [PDF]

open access: yesPLoS Biology, 2008
The eukaryotic genome is packaged as chromatin with nucleosomes comprising its basic structural unit, but the detailed structure of chromatin and its dynamic remodeling in terms of individual nucleosome positions has not been completely defined ...
Sushma Shivaswamy   +5 more
doaj   +1 more source

Genome-wide analysis of interactions between ATP-dependent chromatin remodeling and histone modifications

open access: yesBMC Genomics, 2009
Background ATP-dependent chromatin remodeling and the covalent modification of histones play central roles in determining chromatin structure and function.
Wang Jiang   +6 more
doaj   +1 more source

Differential chromatin accessibility in peripheral blood mononuclear cells underlies COVID-19 disease severity prior to seroconversion

open access: yesScientific Reports, 2022
SARS-CoV-2 infection triggers profound and variable immune responses in human hosts. Chromatin remodeling has been observed in individuals severely ill or convalescing with COVID-19, but chromatin remodeling early in disease prior to anti-spike protein ...
Nicholas S. Giroux   +23 more
doaj   +1 more source

Engineered Chromatin Remodeling Proteins for Precise Nucleosome Positioning

open access: yesCell Reports, 2019
Summary: Regulation of chromatin structure is essential for controlling access of DNA to factors that require association with specific DNA sequences. Here we describe the development and validation of engineered chromatin remodeling proteins (E-ChRPs ...
Drake A. Donovan   +7 more
doaj   +1 more source

Basis of specificity for a conserved and promiscuous chromatin remodeling protein

open access: yeseLife, 2021
Eukaryotic genomes are organized dynamically through the repositioning of nucleosomes. Isw2 is an enzyme that has been previously defined as a genome-wide, nonspecific nucleosome spacing factor.
Drake A Donovan   +8 more
doaj   +1 more source

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