High-resolution mapping of h1 linker histone variants in embryonic stem cells. [PDF]
H1 linker histones facilitate higher-order chromatin folding and are essential for mammalian development. To achieve high-resolution mapping of H1 variants H1d and H1c in embryonic stem cells (ESCs), we have established a knock-in system and shown that ...
Kaixiang Cao +15 more
doaj +1 more source
The multicopy gene Sly represses the sex chromosomes in the male mouse germline after meiosis. [PDF]
Studies of mice with Y chromosome long arm deficiencies suggest that the male-specific region (MSYq) encodes information required for sperm differentiation and postmeiotic sex chromatin repression (PSCR).
Affara, Nabeel A. +6 more
core +3 more sources
HAC stability in murine cells is influenced by nuclear localization and chromatin organization
Background Human artificial chromosomes (HAC) are small functional extrachromosomal elements, which segregate correctly during each cell division. In human cells, they are mitotically stable, however when the HAC are transferred to murine cells they show
Volpi Emanuela V +4 more
doaj +1 more source
A new model of sperm nuclear architecture following assessment of the organization of centromeres and telomeres in three-dimensions [PDF]
The organization of chromosomes in sperm nuclei has been proposed to possess a unique “hairpin-loop” arrangement, which is hypothesized to aid in the ordered exodus of the paternal genome following fertilization. This study simultaneously assessed the 3D
Ioannou, Dimitirios +3 more
core +1 more source
Mutations in MECP2, encoding methyl CpG binding protein 2, cause the neurodevelopmental disorder Rett syndrome. MeCP2 is an abundant nuclear protein that binds to chromatin and modulates transcription in response to neuronal activity.
Malaika K. Singleton +6 more
doaj +1 more source
Molecular effects of dADD1 misexpression in chromatin organization and transcription
Background dADD1 and dXNP proteins are the orthologs in Drosophila melanogaster of the ADD and SNF2 domains, respectively, of the ATRX vertebrate’s chromatin remodeler, they suppress position effect variegation phenotypes and participate in ...
Silvia Meyer-Nava +3 more
doaj +1 more source
Tissue-specific differences in the spatial interposition of X-chromosome and 3R chromosome regions in the malaria mosquito Anopheles messeae Fall. [PDF]
Spatial organization of a chromosome in a nucleus is very important in biology but many aspects of it are still generally unresolved. We focused on tissue-specific features of chromosome architecture in closely related malaria mosquitoes, which have ...
Gleb Artemov +3 more
doaj +1 more source
One of the most popular tools for species discovery and resolution is the DNA barcode, typically based on the cytochrome c oxidase I (COI) gene. However, other non-genic barcodes are available for Diptera.
Peter H. Adler, Shaoming Huang
doaj +1 more source
C-banding, fluorescent staining and NOR location in holokinetic chromosomes of bugs of the Neotropical genus Antiteuchus (Heteroptera: Pentatomidae: Discocephalinae) [PDF]
Different cytogenetic techniques including C-banding, base-specific fluorochromes and silver nitrate staining were used to compare the karyotypes of three species of bugs, representatives of the Neotropical genus Antiteuchus, namely A.
de Souza, Maria José, Lanzone, Cecilia
core +1 more source
The giant, polytene chromosomes of Simulium carthusiense Grenier & Dorier, 1959 were mapped, and all rearrangements were resolved relative to the standard banding sequence for the S. vernum group.
Peter H. ADLER, Gunther SEITZ
doaj +1 more source

