Results 51 to 60 of about 5,729 (189)

Ethanol Alters DNMT1/3a/3b Expression Profile, Promotes Persistent DNA Hypomethylation in Human Brain Endothelial Cells and Impairs Late Cortical Angiogenesis

open access: yesJournal of Neurochemistry, Volume 170, Issue 2, February 2026.
Ethanol exposure alters brain endothelial cell function and blood–brain barrier integrity. In human brain microcapillary endothelial cells (HBMEC) and mouse brain endothelial cells (MBEC) from a prenatal alcohol exposure (PAE) model, ethanol increased DNA methyltransferas‐1 (DNMT1) activity and reduced DNA methylation, affecting DNMT3a/3b, methyl‐CpG ...
Michele Siqueira   +6 more
wiley   +1 more source

Comparative Study of Spermatogenesis and Nucleolar Behavior in Testicular Lobes of Euschistus heros (Heteroptera: Pentatomidae)

open access: yesPsyche: A Journal of Entomology, 2010
In some testicular lobes of the Pentatomidae there may be occurrence of atypical spermatogenesis or polymegaly, leading to the production of nonfertile sperm.
Hederson Vinicius de Souza   +1 more
doaj   +1 more source

Zipping up the Synaptonemal Complex: Pathways to Homologous Chromosome Synapsis

open access: yesBioEssays, Volume 48, Issue 1, January 2026.
The synaptonemal complex (SC) is a conserved protein structure that assembles between homologous chromosomes during meiosis. Here, we review pathways promoting homologous synapsis across model organisms, examining coordination with homolog pairing and recombination, spatiotemporal regulation of SC assembly, and the conserved molecular modules coupling ...
Ariel L. Gold, Yumi Kim
wiley   +1 more source

Changes in nuclear phenotypes following cold shock in Panstrongylus megistus (Burmeister)

open access: yesMemorias do Instituto Oswaldo Cruz, 2000
The nuclear phenotypes of Malpighian tubule epithelial cells of 5th instar male nymphs of the blood-sucking insect Panstrongylus megistus were studied immediately after a short (1 h) cold shock at 0ºC, and 10 and 30 days later.
Simone L Garcia   +3 more
doaj   +1 more source

Robertsonian chromosomes and the nuclear architecture of mouse meiotic prophase spermatocytes [PDF]

open access: yes, 2014
BACKGROUND: The nuclear architecture of meiotic prophase spermatocytes is based on higher-order patterns of spatial associations among chromosomal domains from different bivalents.
Catalina Manieu   +7 more
core   +2 more sources

Karyotyping and Distribution Patterns of Endemic Chinese Lilies: Insights Into Their Conservation Under Climate Change

open access: yesEcology and Evolution, Volume 16, Issue 1, January 2026.
This study integrates cytogenetic and ecological analyses of two endemic Chinese alpine lilies, Lilium lophophorum (2n = 24) and L. nanum (2n = 48), to establish a foundational understanding of their chromosomal diversity and distribution patterns. We document substantial intraspecific karyotypic variation in diploid L.
Tengfei Gui   +5 more
wiley   +1 more source

Cytogenetics and cytotaxonomy of some Brazilian species of Cymbidioid orchids

open access: yesGenetics and Molecular Biology, 2000
The Cymbidioid phylad presents the widest chromosome number variation among orchids, with records varying from 2n = 10 in Psygmorchis pusilla to 2n = 168 in two species of Oncidium.
Leonardo Pessoa Félix, Marcelo Guerra
doaj   +1 more source

Fruit Flies Provide New Insights in Low-Radiation Background Biology at the INFN Underground Gran Sasso National Laboratory (LNGS) [PDF]

open access: yes, 2018
Deep underground laboratories (DULs) were originally created to host particle, astroparticle or nuclear physics experiments requiring a low-background environment with vastly reduced levels of cosmic-ray particle interference. More recently, the range of
Cenci, G.   +5 more
core   +1 more source

ATRX: From Chromatin Remodeling to Disease

open access: yesgenesis, Volume 63, Issue 6, December 2025.
ABSTRACT Chromatin remodeling proteins are evolutionarily conserved factors involved in a wide range of biological processes. In this review, we describe ATRX, a chromatin remodeling protein belonging to the SWI/SNF2 family. Its association with different protein complexes, and its roles in embryonic development, sexual differentiation, as well as ...
Mauro Magaña‐Acosta   +1 more
wiley   +1 more source

Tau promotes neurodegeneration through global chromatin relaxation [PDF]

open access: yes, 2014
The microtubule-associated protein tau is involved in a number of neurodegenerative disorders, including Alzheimer’s disease (AD). Previous studies link oxidative stress and subsequent DNA damage to neuronal death in AD and related tauopathies. Since DNA
Feany, Mel B.   +3 more
core   +1 more source

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