Results 41 to 50 of about 10,432 (143)
Approaches to analysis of chromosome conformation capture data
, 2022 The three-dimensional structure of the genome has a rising impact in the research to understand the regulatory mechanisms in eukaryotic cells. Expression-based methods like RNA-Seq can show if a gene is active or inactive; however, they cannot explain ...
Wolff, Joachim
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The DLO Hi-C Tool for Digestion-Ligation-Only Hi-C Chromosome Conformation Capture Data Analysis
, 2020 It is becoming increasingly important to understand the mechanism of regulatory elements on target genes in long-range genomic distance. 3C (chromosome conformation capture) and its derived methods are now widely applied to investigate three-dimensional (
Hao Jiang +6 more
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High-resolution circular chromosome conformation capture assay
, 2008 The pioneering chromosome conformation capture (3C) method provides the opportunity to study chromosomal folding in the nucleus. It is based on formaldehyde cross-linking of living cells followed by enzyme digestion, intramolecular ligation and ...
Gondor, A +8 more
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Systematic evaluation of chromosome conformation capture assays [preprint]
, 2021 This article is a preprint. Preprints are preliminary reports of work that have not been certified by peer review. The PDF available for download is Version 2 of this preprint. The complete version history of this preprint is available at bioRxiv. Full
Maehr, Rene +13 more
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The three 'C' s of chromosome conformation capture: controls, controls, controls
, 2011 Transcription regulation in higher eukaryotes is controlled by regulatory elements such as enhancers that are recognized by transcription factors. In many cases regulatory elements can be located at distances up to several megabases from their target ...
Dekker, Job
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Orchestrating chromosome conformation capture analysis with Bioconductor
Genome-wide chromatin conformation capture assays provide formidable insights into the spatial organization of genomes. However, due to the complexity of the data structure, their integration in multi-omics workflows remains challenging.
Bignaud, Amaury +14 more
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Actual ligation frequencies in the chromosome conformation capture procedure.
, 2013 Chromosome conformation capture (3C) and derivative experimental procedures are used to estimate the spatial proximity between different genomic elements, thus providing information about the 3D organization of genomic domains and whole genomes within ...
Sergey V Razin +5 more
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Principle of chromosome conformation capture (3C).
, 2021 Black lines in the enlarged digested species represents chromatin. Green rectangle represents HspN ORF, red rectangle represents HspC ORF and black oval represents proteins bound to the chromatin.
Vinithra Iyer (11478736) +6 more
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How best to identify chromosomal interactions: a comparison of approaches.
, 2017 Chromosome conformation capture (3C) methods are central to understanding the link between nuclear structure and function, and the physical interactions between distal regulatory elements and promoters.
Oudelaar, Marieke +3 more
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A cautionary note on the use of chromosome conformation capture in plants [PDF]
, 2017 Background The chromosome conformation capture (3C) technique is a method to study chromatin interactions at specific genomic loci. Initially established for yeast the 3C technique has been adapted to plants in recent years in order to study chromatin ...
Maike Stam +11 more
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