Results 21 to 30 of about 10,432 (143)

Peer Review #1 of "Deconvoluting simulated metagenomes: the performance of hard- and soft- clustering algorithms applied to metagenomic chromosome conformation capture (3C) (v0.1)"

open access: gold, 2016
Matthew Z. DeMaere   +99 more
openalex   +3 more sources

Visualization and data exploration of chromosome conformation capture data using Voronoi diagrams with v3c-viz [PDF]

open access: yes, 2023
Chromosome conformation capture (3C) sequencing approaches, like Hi-C or micro-C, allow for an unbiased view of chromatin interactions. Most analysis methods rely on so-called interaction matrices, which are derived from counting read pairs in bins of ...
Race, A.M., Fuchs, A., Chung, H.R.
core   +1 more source

Analysis of β-globin chromatin micro-environment using a novel 3C variant, 4Cv [PDF]

open access: yes, 2010
Copyright: © 2010 Pink et al.Higher order chromatin folding is critical to a number of developmental processes, including the regulation of gene expression.
Christopher H Eskiw   +17 more
core   +1 more source

Systematic evaluation of chromosome conformation capture assays

open access: yes, 2021
Chromosome conformation capture (3C) assays are used to map chromatin interactions genome-wide. Chromatin interaction maps provide insights into the spatial organization of chromosomes and the mechanisms by which they fold.
Maehr, Rene   +15 more
core   +1 more source

Capture-C: a modular and flexible method for high-resolution chromosome conformation capture

open access: yes, 2022
Chromosome conformation capture (3C) methods measure the spatial proximity between DNA elements in the cell nucleus. Many methods have been developed to sample 3C material, including the Capture-C family of protocols.
Rue-Albrecht, K.   +17 more
core   +2 more sources

Data_Sheet_1_Investigation of the Basic Steps in the Chromosome Conformation Capture Procedure.pdf

open access: yes, 2021
A constellation of chromosome conformation capture methods (С-methods) are an important tool for biochemical analysis of the spatial interactions between DNA regions that are separated in the primary sequence.
Yulii V. Shidlovskii (3838981)   +3 more
core   +1 more source

Generating Chromosome Geometries in a Minimal Cell From Cryo-Electron Tomograms and Chromosome Conformation Capture Maps [PDF]

open access: yes, 2021
JCVI-syn3A is a genetically minimal bacterial cell, consisting of 493 genes and only a single 543 kbp circular chromosome. Syn3A’s genome and physical size are approximately one-tenth those of the model bacterial organism Escherichia coli’s, and the ...
John I. Glass   +23 more
core   +1 more source

Randomized ligation control for chromosome conformation capture

open access: yes, 2015
In experiments using chromosome conformation capture followed by PCR (3C-PCR) or chromosome conformation capture carbon copy (5C), it is critical to control for intrinsic biases in the restriction fragments of interest and the probes or primers used for ...
Dekker, Job, Belton, Jon-Matthew
core   +1 more source

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