Results 11 to 20 of about 10,432 (143)

3C-seq-captured chromosome conformation of the hyperthermophilic archaeon Thermofilum adornatum [PDF]

open access: green, 2021
Abstract Three-dimensional structure of chromosomes displays diverse patterns across the tree of life, with compartments, interaction domains and loops being quite universally observed. The archaeal kingdom remains understudied to this extent so far, despite representing an interesting area from evolutionary and other perspectives.
Andrey Sobolev   +7 more
openalex   +2 more sources

Chromosome Conformation Capture (3C) in Budding Yeast [PDF]

open access: bronzeCold Spring Harbor Protocols, 2015
Chromosome conformation capture (3C) is a method for studying chromosomal organization that takes advantage of formaldehyde cross-linking to measure the spatial association of two pieces of chromatin. The 3C method begins with whole-cell formaldehyde fixation of chromatin.
Jon-Matthew Belton, Job Dekker
openalex   +4 more sources

The macro and micro of chromosome conformation capture

open access: yesWiley Interdisciplinary Reviews: Developmental Biology, 2021
The 3D organization of the genome facilitates gene regulation, replication, and repair, making it a key feature of genomic function and one that remains to be properly understood.
Viraat Y Goel, Anders S Hansen
exaly   +2 more sources

Detection of Short-Range Chromatin Interactions by Chromosome Conformation Capture (3C) in Yeast [PDF]

open access: closed, 2014
We describe a modified 3C ("chromosome conformation capture") protocol for detection of transient, short-range chromatin interactions in the yeast Saccharomyces cerevisiae. 3C was initially described by Job Dekker and involves formaldehyde cross-linking to stabilize transient chromatin interactions, followed by restriction digestion, ligation, and ...
Badri Nath Singh, Michael Hampsey
openalex   +3 more sources

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