Chromosome-level haplotype-resolved assembly of highly heterozygous grass genomes with PhaseGrass [PDF]
Nature CommunicationsCurrent methods to generate haplotype-resolved assemblies for highly heterozygous genomes suffer from reference bias when relying on reference-based phasing or may generate imbalanced haplomes when relying on graph-based phasing.
Yutang Chen +6 more
doaj +2 more sources
Genomic variance partitioning of carcass and meat quality traits in Angus beef cattle [PDF]
Frontiers in Veterinary ScienceThis study aimed to partition the genomic variance of carcass weight (CW), marbling score (MS), rib-eye area (REA), and back fat thickness (BFT) traits in Angus beef cattle into components associated with minor allele frequency (MAF) bins, functional ...
Hasan Baneh +3 more
doaj +2 more sources
eLife, 2022 Three-component ParABS partition systems ensure stable inheritance of many bacterial chromosomes and low-copy-number plasmids. ParA localizes to the nucleoid through its ATP-dependent nonspecific DNA-binding activity, whereas centromere-like parS-DNA and
Andrea Volante +2 more
doaj +1 more source
The internal organization of mycobacterial partition assembly: does the DNA wrap a protein core? [PDF]
PLoS ONE, 2012 Before cell division in many bacteria, the ParBs spread on a large segment of DNA encompassing the origin-proximal parS site(s) to form the partition assembly that participates in chromosome segregation.
Shuo Qian +3 more
doaj +1 more source
Orderly Replication and Segregation of the Four Replicons of Burkholderia cenocepacia J2315. [PDF]
PLoS Genetics, 2016 Bacterial genomes typically consist of a single chromosome and, optionally, one or more plasmids. But whole-genome sequencing reveals about ten per-cent of them to be multipartite, with additional replicons which by size and indispensability are ...
Wen-Li Du +6 more
doaj +1 more source
Partition complex structure can arise from sliding and bridging of ParB dimers
Nature Communications, 2023 In many bacteria, chromosome segregation requires the association of ParB to the parS-containing centromeric region to form the partition complex. However, the structure and formation of this complex have been unclear.
Lara Connolley +3 more
doaj +1 more source
A discrete transition zone organizes the topological and regulatory autonomy of the adjacent tfap2c and bmp7 genes. [PDF]
PLoS Genetics, 2015 Despite the well-documented role of remote enhancers in controlling developmental gene expression, the mechanisms that allocate enhancers to genes are poorly characterized.
Taro Tsujimura +5 more
doaj +1 more source
The two Cis-acting sites, parS1 and oriC1, contribute to the longitudinal organisation of Vibrio cholerae chromosome I. [PDF]
PLoS Genetics, 2014 The segregation of bacterial chromosomes follows a precise choreography of spatial organisation. It is initiated by the bipolar migration of the sister copies of the replication origin (ori).
Ariane David +5 more
doaj +1 more source
Male meiotic spindle features that efficiently segregate paired and lagging chromosomes
eLife, 2020 Chromosome segregation during male meiosis is tailored to rapidly generate multitudes of sperm. Little is known about mechanisms that efficiently partition chromosomes to produce sperm.
Gunar Fabig +9 more
doaj +1 more source
IMACULAT - an open access package for the quantitative analysis of chromosome localization in the nucleus. [PDF]
PLoS ONE, 2013 The alteration in the location of the chromosomes within the nucleus upon action of internal or external stimuli has been implicated in altering genome function.
Ishita Mehta +2 more
doaj +1 more source