Vibrio cholerae Chromosome Partitioning without Polar Anchoring by HubP
Genes, 2022 Partition systems are widespread among bacterial chromosomes. They are composed of two effectors, ParA and ParB, and cis acting sites, parS, located close to the replication origin of the chromosome (oriC). ParABS participate in chromosome segregation, at least in part because they serve to properly position sister copies of oriC.
Possoz, Christophe +4 more
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Evidence for a DNA-relay mechanism in ParABS-mediated chromosome segregation
eLife, 2014 The widely conserved ParABS system plays a major role in bacterial chromosome segregation. How the components of this system work together to generate translocation force and directional motion remains uncertain.
Hoong Chuin Lim +5 more
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Temporal fuzzy association rule mining with 2-tuple linguistic representation [PDF]
, 2012 This paper reports on an approach that contributes towards the problem of discovering fuzzy association rules that exhibit a temporal pattern. The novel application of the 2-tuple linguistic representation identifies fuzzy association rules in a temporal
Ahmadi, Samad +3 more
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Subsampling Technique to Estimate Variance Component for UK-Biobank Traits
Frontiers in Genetics, 2021 The estimation of heritability has been an important question in statistical genetics. Due to the clear mathematical properties, the modified Haseman–Elston regression has been found a bridge that connects and develops various parallel heritability ...
Ting Xu +5 more
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A nonparametric Bayesian approach to the rare type match problem
, 2022 The "rare type match problem" is the situation in which the suspect's DNA profile, matching the DNA profile of the crime stain, is not in the database of reference.
Cereda, Giulia, Gill, Richard D.
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The extrusion-capture model for chromosome partitioning in bacteria [PDF]
Genes & Development, 2001 Successful cellular reproduction requires accurate duplication and partitioning (segregation) of the genome. Failure to correctly partition the sister genomes results in aneuploidy. The consequences of these errors range from loss of normal cellular function (e.g., the loss of normal growth controls in tumor cells) to cell death.
K P, Lemon, A D, Grossman
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Kinetics of large-scale chromosomal movement during asymmetric cell division in Escherichia coli. [PDF]
PLoS Genetics, 2017 Coordination between cell division and chromosome replication is essential for a cell to produce viable progeny. In the commonly accepted view, Escherichia coli realize this coordination via the accurate positioning of its cell division apparatus ...
Jaana Männik +3 more
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Ultraaccurate genome sequencing and haplotyping of single human cells. [PDF]
, 2017 Accurate detection of variants and long-range haplotypes in genomes of single human cells remains very challenging. Common approaches require extensive in vitro amplification of genomes of individual cells using DNA polymerases and high-throughput short ...
Bafna, Vineet +6 more
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Accounting for heteroscedasticity and censoring in chromosome partitioning analyses [PDF]
Evolution Letters, 2018 AbstractA fundamental assumption in quantitative genetics is that traits are controlled by many loci of small effect. Using genomic data, this assumption can be tested using chromosome partitioning analyses, where the proportion of genetic variance for a trait explained by each chromosome (h2c), is regressed on its size.
Petri Kemppainen, Arild Husby
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Integrative Model-based clustering of microarray methylation and expression data [PDF]
, 2012 In many fields, researchers are interested in large and complex biological processes. Two important examples are gene expression and DNA methylation in genetics.
Booth, James G. +3 more
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