Results 111 to 120 of about 995,917 (290)

Can entropy save bacteria? [PDF]

Suckjoon Jun and Andrew Wright, Nature Reviews Microbiology, August issue (2010), 2008
This article presents a physical biology approach to understanding organization and segregation of bacterial chromosomes. The author uses a "piston" analogy for bacterial chromosomes in a cell, which leads to a phase diagram for the organization of two athermal chains confined in a closed geometry characterized by two length scales (length and width ...
arxiv  

Chromosome segregation drives division site selection in Streptococcus pneumoniae

Proceedings of the National Academy of Sciences of the United States of America, 2016
Significance Precise cell division is crucial for all cellular life. In the pneumococcus, which kills more than a million people annually, the protein MapZ was recently identified as a marker for the division site.
Renske van Raaphorst, M. Kjos, J. Veening   +2 more
semanticscholar   +1 more source

Resolving Chromosome Segregation in Bacteria

Microbial Physiology, 2006
Bacterial chromosomes are evenly distributed between daughter cells, however no equivalent eukaryotic mitotic apparatus has been identified yet. Nevertheless, an advance in our understanding of the dynamics of the bacterial chromosome has been accomplished in recent years by adopting fluorescence microscopy techniques to visualize living bacterial ...
Ronen, Hazan, Hazan, Ronen, Sigal, Ben-Yehuda, Ben-Yehuda, Sigal   +3 more
openaire   +3 more sources

Chromosome segregation in lymphocyte hybrids [PDF]

Hereditas, 2009
Chromosome segregation was studied in mouse/human and mouse/mouse T-lymphocyte hybrids, and in mouse/human, mouse/rabbit and mouse/rat B-lymphocyte hybrids. Chromosome loss was not random, it was moderate in mouse/mouse and mouse/rat lymphocyte hybrids, but extensive in mouse/human and mouse/rabbit lymphocyte hybrids.
Schroder, J, Sutinen, M, Suomalainen, H A   +2 more
openaire   +3 more sources

CENP-A Is Dispensable for Mitotic Centromere Function after Initial Centromere/Kinetochore Assembly [PDF]

, 2016
Human centromeres are defined by chromatin containing the histone H3 variant CENP-A assembled onto repetitive alphoid DNA sequences. By inducing rapid, complete degradation of endogenous CENP-A, we now demonstrate that once the first steps of centromere ...
Barra V., Cleveland D. W., Dumont M., Fachinetti D., Herve S., Hoffmann S., Ly P., McMahon M. A., Nechemia-Arbely Y.   +8 more
core   +1 more source

Mitosis-specific acetylation tunes Ran effector binding for chromosome segregation

Journal of Molecular Cell Biology, 2017
Stable transmission of genetic information during cell division requires faithful mitotic spindle assembly and chromosome segregation. The Ran GTPase plays a key role in mitotic spindle assembly.
Xiaolin Bao, Heng Liu, Xing Liu, Ke Ruan, Yonghui Zhang, Zhiyong Zhang, Q. Hu, Y. Liu, Saima Akram, Jiahai Zhang, Q. Gong, Wenwen Wang, Xiao Yuan, Jian Li, Lingli Zhao, Zhen Dou, Ruijun Tian, X. Yao, Jihui Wu, Yunyu Shi   +19 more
semanticscholar   +1 more source

Mitotic antipairing of homologous and sex chromosomes via spatial restriction of two haploid sets. [PDF]

, 2018
Pairing homologous chromosomes is required for recombination. However, in nonmeiotic stages it can lead to detrimental consequences, such as allelic misregulation and genome instability, and is rare in human somatic cells.
Hua, Lisa L, Mikawa, Takashi
core   +1 more source

Bacterial Chromosome Organization and Segregation [PDF]

Cold Spring Harbor Perspectives in Biology, 2010
Bacterial chromosomes are generally approximately 1000 times longer than the cells in which they reside, and concurrent replication, segregation, and transcription/translation of this crowded mass of DNA poses a challenging organizational problem. Recent advances in cell-imaging technology with subdiffraction resolution have revealed that the bacterial
Esteban Toro, Lucy Shapiro
openaire   +3 more sources

Cdc14 and PP2A Phosphatases Cooperate to Shape Phosphoproteome Dynamics during Mitotic Exit

Cell Reports, 2019
Summary: Temporal control over protein phosphorylation and dephosphorylation is crucial for accurate chromosome segregation and for completion of the cell division cycle during exit from mitosis. In budding yeast, the Cdc14 phosphatase is thought to be a
Sandra A. Touati, Lorena Hofbauer, Andrew W. Jones, Ambrosius P. Snijders, Gavin Kelly, Frank Uhlmann   +5 more
doaj  

Error-prone chromosome-mediated spindle assembly favors chromosome segregation defects in human oocytes

Science, 2015
Earliest stages of human development revealed Most of our knowledge about meiosis in mammalian oocytes stems from studies of mouse oocytes. However, chromosome segregation in mouse oocytes is much more reliable than in human oocytes.
Z. Holubcová, M. Blayney, K. Elder, M. Schuh   +3 more
semanticscholar   +1 more source