Results 11 to 20 of about 1,033,685 (362)

Double-checking chromosome segregation

Journal of Cell Biology, 2023
Maiato and Silva discuss the origin and fate of chromosome segregation errors that satisfy the spindle assembly checkpoint, focusing on anaphase surveillance/correction mechanisms and post-mitotic clearance pathways.
H. Maiato, Sónia Silva
semanticscholar   +3 more sources

Age-cumulative effect of REC8 reduction on meiotic chromosome segregation errors in mice

Reproductive and Developmental Medicine, 2021
Objective: This study aimed to explore the relationship between cohesin subunit REC8 reduction and meiosis chromosome segregation errors in the ovary. Methods: Rec8+/− mice were generated using CRIPSR/Cas9 gene editing.
Li-Yuan Tian, Ling Zhang, Cheng-Qiu Tao, Xiao-Qi Lin, Feng Zhang, Bin Zhang   +5 more
doaj   +2 more sources

Sod1 deficiency in mouse oocytes during in vitro maturation increases chromosome segregation errors with a reduced BUBR1 at kinetochore [PDF]

Reproductive Medicine and Biology
Purpose This study aimed to investigate the molecular mechanisms associated with chromosome segregation errors caused by intrinsic oxidative stress during in vitro oocyte maturation (IVM) using oocytes from Sod1‐deficient (Sod1KO) mice.
Mitsuru Nago, Masumi Yanai, Mika Ishii, Yasuko Sato, Kazuharu Odajima, Naoko Kimura   +5 more
doaj   +2 more sources

Human female meiosis revised: new insights into the mechanisms of chromosome segregation and aneuploidies from advanced genomics and time-lapse imaging [PDF]

Human Reproduction Update, 2017
Antonio Capalbo, Eva R. Hoffmann, Danilo Cimadomo, Filippo Maria Ubaldi, Laura Rienzi   +4 more
openalex   +2 more sources

The mitotic ATR-Chk1 pathway promotes CDK1 activity for faithful chromosome segregation. [PDF]

Cell Rep
Joo YK, Parrado CR, Li W, Yang R, Black E, Bleichert F, Liu Y, Kabeche L.   +7 more
europepmc   +3 more sources

Chromosome Segregation [PDF]

Definitions, 2020

semanticscholar   +2 more sources

Arabidopsis Cell Division Cycle 20.1 Is Required for Normal Meiotic Spindle Assembly and Chromosome Segregation [PDF]

The Plant Cell, 2015
Baixiao Niu, Liudan Wang, Liangsheng Zhang, Ding Ren, Ren Ren, Gregory P. Copenhaver, Hong Mā, Yingxiang Wang   +7 more
openalex   +2 more sources

Chromosome Segregation in the Oocyte: What Goes Wrong during Aging

International Journal of Molecular Sciences, 2022
Human female fertility and reproductive lifespan decrease significantly with age, resulting in an extended post-reproductive period. The central dogma in human female reproduction contains two important aspects.
Marta Wasielak-Politowska, P. Kordowitzki   +1 more
semanticscholar   +1 more source

Cohesin and chromosome segregation [PDF]

Current Biology, 2018
Cohesin is a ring-shaped protein complex that organises the genome, enabling its condensation, expression, repair and transmission. Cohesin is best known for its role in chromosome segregation, where it provides the cohesion that is established between the two newly duplicated sister chromatids during S phase.
V. Makrantoni, A. Marston
semanticscholar   +4 more sources

Mechanisms for Chromosome Segregation in Bacteria

Frontiers in Microbiology, 2021
The process of DNA segregation, the redistribution of newly replicated genomic material to daughter cells, is a crucial step in the life cycle of all living systems.
Christos Gogou, A. Japaridze, C. Dekker
semanticscholar   +1 more source