Allelic segregation and independent assortment in T. brucei crosses: proof that the genetic system is Mendelian and involves meiosis [PDF]
The genetic system on Trypanosoma brucei has been analysed by generating large numbers of independent progeny clones from two crosses, one between two cloned isolates of Trypanosoma brucei brucei and one between cloned isolates of T. b.
Turner, CMR +15 more
core +1 more source
Chromosome segregation in lymphocyte hybrids [PDF]
Chromosome segregation was studied in mouse/human and mouse/mouse T-lymphocyte hybrids, and in mouse/human, mouse/rabbit and mouse/rat B-lymphocyte hybrids. Chromosome loss was not random, it was moderate in mouse/mouse and mouse/rat lymphocyte hybrids, but extensive in mouse/human and mouse/rabbit lymphocyte hybrids.
Schroder, J +2 more
openaire +2 more sources
The role of chromosome segregation and nuclear organisation in human subfertility [PDF]
Spermatogenesis is central to successful sexual reproduction, producing large numbers of haploid motile male gametes. Throughout this process, a series of equational and reductional chromosome segregation precedes radical repackaging of the haploid ...
Fowler, K. +5 more
core +1 more source
Chromosomal macrodomains and associated proteins : implications for DNA organization and replication in gram negative bacteria [PDF]
The Escherichia coli chromosome is organized into four macrodomains, the function and organisation of which are poorly understood. In this review we focus on the MatP, SeqA, and SlmA proteins that have recently been identified as the first examples of ...
Kalmykowa, Olga J. +14 more
core +1 more source
Cdc14 and PP2A Phosphatases Cooperate to Shape Phosphoproteome Dynamics during Mitotic Exit
Summary: Temporal control over protein phosphorylation and dephosphorylation is crucial for accurate chromosome segregation and for completion of the cell division cycle during exit from mitosis. In budding yeast, the Cdc14 phosphatase is thought to be a
Sandra A. Touati +5 more
doaj +1 more source
SMC is recruited to oriC by ParB and promotes chromosome segregation in Streptococcus pneumoniae [PDF]
Segregation of replicated chromosomes is an essential process in all organisms. How bacteria, such as the oval-shaped human pathogen Streptococcus pneumoniae, efficiently segregate their chromosomes is poorly understood.
Stephan Gruber +19 more
core +3 more sources
On the origin of crossover interference : a chromosome oscillatory movement (COM) model [PDF]
Background: It is now nearly a century since it was first discovered that crossovers between homologous parental chromosomes, originating at the Prophase stage of Meiosis I, are not randomly placed.
Maj A Hultén +2 more
core +1 more source
Double-checking chromosome segregation
Enduring chromosome segregation errors represent potential threats to genomic stability due to eventual chromosome copy number alterations (aneuploidy) and formation of micronuclei—key intermediates of a rapid mutational process known as chromothripsis that is found in cancer and congenital disorders.
Helder Maiato, Sónia Silva
openaire +2 more sources
Nuclear Organization and Chromosome Segregation [PDF]
The genetic information underlying plant form and function is contained within the cell nucleus in the form of complex, dynamic DNA–protein structures—the chromosomes. The faithful transmission of these structures during mitosis and meiosis requires extensive chromosome reorganization and ...
A E, Franklin, W Z, Cande
openaire +3 more sources
Both Chromosome Decondensation and Condensation Are Dependent on DNA Replication in C.elegans Embryos [PDF]
During cell division, chromatin alternates between a condensed state to facilitate chromosome segregation and a decondensed form when DNA replicates.
Blow, J. Julian; id_orcid +11 more
core +1 more source

