Results 21 to 30 of about 191,348 (320)

Assessing Budding Yeast Phosphoproteome Dynamics in a Time-Resolved Manner using TMT10plex Mass Tag Labeling

open access: yesSTAR Protocols, 2020
Summary: Amine-reactive Tandem Mass Tag 10plex (TMT10plex) labeling permits multiplexed protein identification and quantitative analysis by tandem mass spectrometry (MS/MS).
Andrew W. Jones   +4 more
doaj   +1 more source

Separase prevents genomic instability by controlling replication fork speed [PDF]

open access: yes, 2016
Proper chromosome segregation is crucial for preserving genomic integrity, and errors in this process cause chromosome mis-segregation, which may contribute to cancer development.
Cucco, Francesco   +11 more
core   +6 more sources

A global view of substrate phosphorylation and dephosphorylation during budding yeast mitotic exit

open access: yesMicrobial Cell, 2018
The cell cycle is the process by which a cell duplicates its DNA during S-phase and divides its chromosomes during M-phase, creating two genetically identical daughter cells.
Sandra A. Touati, Frank Uhlmann
doaj   +1 more source

Prime movers : mechanochemistry of mitotic kinesins [PDF]

open access: yes, 2014
Mitotic spindles are self-organizing protein machines that harness teams of multiple force generators to drive chromosome segregation. Kinesins are key members of these force-generating teams.
A Blangy   +184 more
core   +1 more source

Bacterial chromosome segregation [PDF]

open access: yesMicrobiology, 2001
Recent years have witnessed a resurgence of interest in how the bacterial chromosome is organized and how newly replicated chromosomes are faithfully segregated into daughter cells on cell division. In the past, the problem with studying bacterial chromosomes was their lack of any obvious morphology, combined with the lack of ability to readily ...
openaire   +2 more sources

Cohesin and chromosome segregation [PDF]

open access: yesCurrent Biology, 2018
Cohesin is a ring-shaped protein complex that organises the genome, enabling its condensation, expression, repair and transmission. Cohesin is best known for its role in chromosome segregation, where it provides the cohesion that is established between the two newly duplicated sister chromatids during S phase.
Makrantoni, Vasso, Marston, Adele L
openaire   +3 more sources

Securin Is Not Required for Chromosomal Stability in Human Cells [PDF]

open access: yes, 2005
Abnormalities of chromosome number are frequently observed in cancers. The mechanisms regulating chromosome segregation in human cells are therefore of great interest.
Azofeifa   +32 more
core   +4 more sources

CHROMOSOME SEGREGATION MECHANISMS [PDF]

open access: yesGenetics, 1974
ABSTRACT Most aspects of chromosome distribution to the daughter cells in meiosis and mitosis are now understood, at the cellular level. The most striking evidence that the proposed explanation is valid is that it correctly predicts the outcome of experiments on living cells in which the experimenter (1) can determine the distribution of
openaire   +2 more sources

Chromosome Segregation: Correcting Improperly Attached Chromosomes [PDF]

open access: yesCurrent Biology, 2006
Two new studies show that Aurora B kinase corrects improperly attached chromosomes by recruiting molecules necessary for eliminating the bad attachments and by regulating the turnover of the kinetochore fiber.
Zhang, Xin, Walczak, Claire E.
openaire   +2 more sources

The Drosophila histone variant H2A.V works in concert with HP1 to promote kinetochore-driven microtubule formation [PDF]

open access: yes, 2015
Unlike other organisms that have evolved distinct H2A variants for different functions, Drosophila melanogaster has just one variant which is capable of filling many roles.
Cenci, Giovanni, Verni', Fiammetta
core   +1 more source

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