Results 41 to 50 of about 923,115 (353)
A Cohesin-Based Partitioning Mechanism Revealed upon Transcriptional Inactivation of Centromere. [PDF]
PLoS Genetics, 2016 Transcriptional inactivation of the budding yeast centromere has been a widely used tool in studies of chromosome segregation and aneuploidy. In haploid cells when an essential chromosome contains a single conditionally inactivated centromere (GAL-CEN ...
Michael Tsabar +8 more
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Causes and consequences of chromosome segregation error in preimplantation embryos.
Reproduction, 2018 Errors in chromosome segregation are common during the mitotic divisions of preimplantation development in mammalian embryos, giving rise to so-called 'mosaic' embryos possessing a mixture of euploid and aneuploid cells. Mosaicism is widely considered to
Cayetana Vázquez-Diez, G. Fitzharris
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Spo0J and SMC are required for normal chromosome segregation in Staphylococcus aureus
MicrobiologyOpen, 2020 Bacterial chromosome segregation is an essential cellular process that is particularly elusive in spherical bacteria such as the opportunistic human pathogen Staphylococcus aureus.
Helena Chan +2 more
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Bacterial chromosome segregation.
Acta Biochimica Polonica, 2005 In most bacteria two vital processes of the cell cycle: DNA replication and chromosome segregation overlap temporally. The action of replication machinery in a fixed location in the cell leads to the duplication of oriC regions, their rapid separation to the opposite halves of the cell and the duplicated chromosomes gradually moving to the same ...
Aneta A. Bartosik, Grazyna Jagura-Burdzy
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Age-cumulative effect of REC8 reduction on meiotic chromosome segregation errors in mice
Reproductive and Developmental Medicine, 2021 Objective: This study aimed to explore the relationship between cohesin subunit REC8 reduction and meiosis chromosome segregation errors in the ovary. Methods: Rec8+/− mice were generated using CRIPSR/Cas9 gene editing.
Li-Yuan Tian +5 more
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Spindle mechanics and chromosome segregation
Molecular Biology of the Cell, 2019 The Minisymposium “Spindle Mechanics and Chromosome Segregation” featured new and exciting findings related to the spindle and chromosomes during mitosis and meiosis. It covered a range of topics including spindle architecture and mechanics, kinetochore–microtubule interactions, chromosome dynamics at mitotic entry and exit, as well as mitotic errors ...
Daniel W. Gerlich, Iva M. Tolić
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Deregulation of Chromosome Segregation and Cancer [PDF]
Annual Review of Cancer Biology, 2020 The mitotic spindle assembly checkpoint (SAC) is an intricate cell signaling system that ensures the high fidelity and timely segregation of chromosomes during cell division. Mistakes in this process can lead to the loss, gain, or rearrangement of the genetic material. Gross chromosomal aberrations are usually lethal but can cause birth and development
Curtis, Natalie L. +3 more
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The Consequences of Chromosome Segregation Errors in Mitosis and Meiosis
Biology, 2017 Mistakes during cell division frequently generate changes in chromosome content, producing aneuploid or polyploid progeny cells. Polyploid cells may then undergo abnormal division to generate aneuploid cells.
T. Potapova, G. Gorbsky
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Random Chromosome Partitioning in the Polyploid Bacterium Thermus thermophilus HB27
G3: Genes, Genomes, Genetics, 2019 Little is known about chromosome segregation in polyploid prokaryotes. In this study, whether stringent or variable chromosome segregation occurs in polyploid thermophilic bacterium Thermus thermophilus was analyzed.
Haijuan Li
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The role of CSE1L expression in cervical lymph node metastasis of larynx tumors
Brazilian Journal of Otorhinolaryngology, 2021 Introduction: According to international reports, 30–40% of all head and neck cancers are larynx cancers, comprising 1–2.5% of all cancer types. Cervical nodal involvement has been reported to be 40% and 65% in T3 and T4 cases, respectively.
Tuncay Tunccan +7 more
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