Results 101 to 110 of about 5,203 (193)

Chromothripsis and cancer:causes and consequences of chromosome shattering

, 2012
Genomic alterations that lead to oncogene activation and tumour suppressor loss are important driving forces for cancer development. Although these changes can accumulate progressively during cancer evolution, recent studies have revealed that many ...
Jackson, Stephen P, Josep V. Forment, Stephen P. Jackson, Abderrahmane Kaidi, Kaidi, Abderrahmane, Forment, Josep V   +5 more
core   +1 more source

Poster Sessions

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing

, 2018
SummaryChromothripsis is a newly discovered mutational phenomenon involving massive, clustered genomic rearrangements that occurs in cancer and other diseases.
Cheng-Zhong Zhang, Dmitry Gordenin, Isidro Cortés-Ciriano, Youngsook L. Jung, Peter J. Park, null null, June-Koo Lee, Ruibin Xi, Dhawal Jain, Lixing Yang, David S. Pellman, Leszek J. Klimczak   +11 more
core   +1 more source

Publication Only

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Chromothripsis: Breakage-fusion-bridge over and over again

, 2013
The acquisition of massive but localized chromosome translocations, a phenomenon termed chromothripsis, has received widespread attention since its discovery over a year ago.
Martínez-Alonso, Carlos, Sánchez de Diego, Ainhoa, Pascual-Montano, Alberto, Van Wely, Karel H. M., Sánchez Sorzano, Carlos Óscar   +4 more
core   +1 more source

Chromothripsis [PDF]

, 2020
openaire   +1 more source

Chromothripsis Challenges the Germline [PDF]

Molecular Syndromology, 2012
openaire   +2 more sources

Utility of Optical Genome Mapping in the Characterisation of the Global Genomic Architecture of Paediatric Central Nervous System Tumours: A Pilot Study. [PDF]

Neuropathol Appl Neurobiol
Alesi V, Genovese S, Russo S, Giovannoni I, Barresi S, Tancredi C, Pedace L, Arienzo F, Lombardo A, Bontempo P, Agolini E, Calacci C, Morgia A, Calvieri G, Puggioni C, Cardoni A, Cacchione A, Del Baldo G, Colafati GS, Carai A, Mastronuzzi A, Miele E, Abeni D, Locatelli F, Muda AO, Novelli A, Alaggio R, Rossi S.   +27 more
europepmc   +1 more source

Examining the role of extrachromosomal DNA in lung cancer. [PDF]

J Natl Cancer Inst
Khandekar A, Hoang PH, Luebeck J, Díaz-Gay M, Zhao W, McElderry JP, Hartman C, Miraftab M, Lee OW, Barnao KM, Jones K, Hutchinson A, Hicks B, Bergstrom EN, Yang Y, Nowak MA, Rothman N, Pesatori AC, Consonni D, Homer R, Baine MK, Sholl LM, Joubert P, Leduc C, Travis WD, Yang SR, Lan Q, Wedge DC, Yang L, Chanock SJ, Zhang T, Alexandrov LB, Landi MT.   +32 more
europepmc   +1 more source

Genomic landscape and tumor immune microenvironment of osteosarcoma: Bridging mechanistic insights to precision therapeutics. [PDF]

Bone Rep
Yang C, Yu Y, Wang Y, Cai Z, Zhao Y, Ma H, Xu J, Zhu H, Ren T, Tang X, Xie L.   +10 more
europepmc   +1 more source