Results 81 to 90 of about 5,203 (193)

Whole‐genome sequencing of cell‐free DNA for assessment of minimal residual disease in high‐risk smoldering multiple myeloma

HemaSphere, Volume 10, Issue 4, April 2026.
Abstract In multiple myeloma (MM), minimal residual disease (MRD) is an established endpoint for accelerated drug approval but is limited by a need for serial invasive bone marrow (BM) biopsies, which may under‐sample spatial heterogeneity and result in false negativity.
Chrissy Baker, Elizabeth Hill, Dickran Kazandjian, Marios Papadimitriou, Michael Durante, Abhishek Pandey, Bachisio Ziccheddu, Tomas Jelinek, David Coffey, Brian Walker, Ryan Young, Kylee Maclachlan, Neha Korde, Nickoli Parkinson, Zoe R. Goldstein, Alexi Runnels, William F. Hooper, Dan Landau, Nicolas Robine, Francesco Maura, Ola Landgren, Benjamin Diamond   +21 more
wiley   +1 more source

Long-read sequencing reveals chromothripsis in a molecularly unsolved case of Cornelia de Lange syndrome

Frontiers in Genetics
Thanks to a long-read sequencing (LRS) approach, in this study, we have reported a molecularly solved case of a proband with a clinical diagnosis of Cornelia de Lange syndrome (CDLS), which is a multisystemic disorder whose causative molecular defects ...
Ilaria Bestetti, Milena Crippa, Alessandra Sironi, Matteo Bellini, Francesca Tumiatti, Sara Ballabio, Ferruccio Ceriotti, Luigi Memo, Maria Iascone, Lidia Larizza, Palma Finelli, Palma Finelli   +11 more
doaj   +1 more source

Micronuclei-based model system reveals functional consequences of chromothripsis in human cells

eLife, 2019
Cancer cells often harbor chromosomes in abnormal numbers and with aberrant structure. The consequences of these chromosomal aberrations are difficult to study in cancer, and therefore several model systems have been developed in recent years.
Maja Kneissig, Kristina Keuper, Mirjam S de Pagter, Markus J van Roosmalen, Jana Martin, Hannah Otto, Verena Passerini, Aline Campos Sparr, Ivo Renkens, Fenna Kropveld, Anand Vasudevan, Jason M Sheltzer, Wigard P Kloosterman, Zuzana Storchova   +13 more
doaj   +1 more source

Abstracts

Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

Table S2 from Chromothripsis in Human Breast Cancer

, 2020
Chromothripsis scoring by visual and algorithm-based ...
Shaymaa Elgaafary (14945289), Hans-Peter Sinn (14945295), Steffen Hirsch (14913447), Markus Schulze (5173634), Verena Körber (14945286), Aurélie Ernst (686338), Marc Zapatka (14945307), Michiel Bolkestein (14945280), Frauke Devens (14945298), Peter Lichter (7440), Andreas Schneeweiss (14945304), John K.L. Wong (14945283), Felix K.F. Kommoss (14945292), Mario Hlevnjak (247206), Tobias Anzeneder (724335), Thomas Höfer (24033), Petra Schröter (14945301), Verena Thewes (14802146)   +17 more
core   +1 more source

Chromothripsis: a new molecular mechanism in cancer development [PDF]

, 2012
Deep insight on Chromothripsis: a new molecular mechanism in cancer ...
Férec, C, Chen, JM, Cooper, DN
core   +1 more source

Table S6 from Chromothripsis in Human Breast Cancer

, 2020
Differentially expressed genes between cases with and without ...
Shaymaa Elgaafary (14945289), Hans-Peter Sinn (14945295), Steffen Hirsch (14913447), Markus Schulze (5173634), Verena Körber (14945286), Aurélie Ernst (686338), Marc Zapatka (14945307), Michiel Bolkestein (14945280), Frauke Devens (14945298), Peter Lichter (7440), Andreas Schneeweiss (14945304), John K.L. Wong (14945283), Felix K.F. Kommoss (14945292), Mario Hlevnjak (247206), Tobias Anzeneder (724335), Thomas Höfer (24033), Petra Schröter (14945301), Verena Thewes (14802146)   +17 more
core   +1 more source

Chromothripsis [PDF]

Current Biology, 2015
Hatch, Emily M., Hetzer, Martin W.
openaire   +2 more sources

Ultra-high Density SNParray in Neuroblastoma Molecular Diagnostics

Frontiers in Oncology, 2014
Neuroblastoma serves as a paradigm for applying tumor genomic data for determining patient prognosis and thus for treatment allocation. MYCN status, i.e. amplified vs.
Inge M. Ambros, Clemens eBrunner, Reza eAbbasi, Christian eFrech, Peter F. Ambros, Peter F. Ambros   +5 more
doaj   +1 more source

Deregulation and Shattering of Chromosomal Segments Containing Multiple Oncogenic Targets in the Pathogenesis of Diffuse Large B Cell Lymphoma, Not Otherwise Specified (DLBCL, NOS)

DNA
Diffuse large B cell lymphoma, not otherwise specified (DLBCL, NOS) is the most common type of non-Hodgkin lymphoma (NHL). Significant efforts have been focused on utilizing advanced genomic technologies to further subclassify DLBCL, NOS into clinically ...
Ashwini K. Yenamandra, Rebecca B. Smith, Adam C. Seegmiller, Brianna N. Smith, Debra L. Friedman, Christine M. Smith   +5 more
doaj   +1 more source