Results 81 to 90 of about 3,678,002 (282)

Rehabilitation training improves nerve injuries by affecting Notch1 and SYN

open access: yesOpen Medicine, 2020
The aim of this study was to investigate the effects of rehabilitation training on Notch1 and synaptophysin (SYN) levels in brain tissues of rats with chronic cerebral ischemia.
Jing Mao   +4 more
doaj   +1 more source

Systemic Extracerebral Atherosclerotic Burden and Dementia Risk After Incident Stroke

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Stroke survivors are at increased risk of dementia, but clinically accessible markers of risk heterogeneity remain limited. Previous studies have largely examined atherosclerotic disease in individual vascular beds rather than the overall burden of systemic extracerebral atherosclerosis.
Zhexuan Yu   +4 more
wiley   +1 more source

Copine‐4 Paraneoplastic Autoimmune Encephalitis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We characterize copine‐4 (CPNE4)‐IgG and report clinical associations. Among 844 samples with unclassified neural IgGs identified by mouse‐brain indirect immunofluorescence assay over 2 years, 5 samples (serum, 3; CSF, 2) from 3 patients produced a distinctive cerebrum‐restricted synaptic pattern.
Mimi S. Fang   +12 more
wiley   +1 more source

Motor activity and neurological deficit restoration as the result of combined semax and hopantenic acid influence in experimental chronic brain ischemia

open access: yesJournal of Education, Health and Sport
The prevalence and incidence of cerebrovascular pathology, especially chronic progressive forms, is constantly increasing in modern conditions. Treatment of chronic forms of cerebral blood supply insufficiency is of particular relevance.
V. Kirchev
doaj   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonists in Multiple Sclerosis: A Topical Narrative Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The glucagon‐like peptide‐1 (GLP‐1) receptor agonists (RAs) are a relatively new class of drugs that were initially approved by the US Food and Drug Administration to improve glycemic control in patients with type 2 diabetes mellitus and, subsequently, weight reduction in patients with obesity.
Audrey Y. Chang, Farrah J. Mateen
wiley   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

open access: yesArthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos   +2 more
wiley   +1 more source

The Quantitative Analysis of 2-[18F]-A-85380 nAChRs Micro-PET Brain Imaging in Chronic Ischemic Rats with Cognitive Dysfunction in Vivo

open access: yesJournal of Isotopes, 2017
The change of 2-[18F]-A-85380 in chronic ischemia rats with cognitive dysfunction was evaluated by Micro-PET. Chronic cerebral ischemia rat model was made by bilateral common carotid artery ligation.
JIANG Yu-yan;DIAO Yao;YIN Ya-fu;HUANG Le-le;MO Ye-xiong;ZHANG Da-long;LI Ya-ming
doaj  

DIAGNOSTICS OF WALKING DISORDERS IN PATIENTS WITH HYPERTENSION AND CHRONIC BRAIN ISCHEMIA

open access: yes, 2023
The article presents examination data of patients with hypertension, chronic brain ischemia and Leriche's syndrome. It is noted that in patients with concomitant Leriche's syndrome, the process of dysfunction of the central nervous system is aggravated.
Dzhurabekova Aziza Takhirovna   +2 more
openaire   +2 more sources

A Scoping Review and Meta‐Analysis of Proportions of Central Nervous System Manifestations Reported in Patients with Sjögren's Disease

open access: yesArthritis Care &Research, EarlyView.
Objective The objective of this scoping review was to synthesize evidence on the proportion of individuals living with Sjögren's disease who experience central nervous system (CNS) manifestations. Methods We searched MEDLINE (via PubMed) and Embase from 1980 through January 29, 2026, and the ECRI Guidelines Trust from 2020 through January 29, 2026 ...
Arun Varadhachary   +21 more
wiley   +1 more source

Empagliflozin demonstrates neuroprotective and cardioprotective effects by reducing ischemia/reperfusion damage in rat models of ischemic stroke and myocardial infarction

open access: yesScientific Reports
Sodium-glucose co-transporter 2 (SGLT2) inhibitors have demonstrated potential neuroprotective and cardioprotective effects in preliminary studies. This study evaluates the efficacy of empagliflozin (EMPA) in reducing ischemia/reperfusion damage in both ...
Wangde Dai   +5 more
doaj   +1 more source

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