Results 51 to 60 of about 2,747,113 (394)
An Australian Chronic Kidney Disease Biobank to Support Future Research
Open Journal of Bioresources, 2019 The Chronic Kidney Disease (CKD) Biobank is a repository for plasma, erythrocytes, serum, peripheral blood mononuclear cells (PBMCs), DNA, kidney core biopsies, and relevant clinical data.
Evan P. Owens +4 more
doaj +1 more source
Oxidative Stress and Mitochondrial Dysfunction in Chronic Kidney Disease
Cells, 2022 The kidney contains many mitochondria that generate ATP to provide energy for cellular processes. Oxidative stress injury can be caused by impaired mitochondria with excessive levels of reactive oxygen species.
Hsin-Jung Ho, H. Shirakawa
semanticscholar +1 more source
Renal AA-amyloidosis in intravenous drug users - a role for HIV-infection? [PDF]
, 2012 Background: Chronic renal disease is a serious complication of long-term intravenous drug use (IVDU). Recent reports have postulated a changing pattern of underlying nephropathy over the last decades.
Amann, Kerstin Ute +7 more
core +2 more sources
Journal of Diabetes, 2023 Background Glutamate is a major neurotransmitter, although it causes cytotoxicity and inflammation in nonneuronal organs. This study aimed to investigate the metabolic disorders in which glutamate, associated with type 2 diabetes onset, is induced in the
Hyo Jung Lee +7 more
doaj +1 more source
Chronic Kidney Disease Diagnosis and Management: A Review.
Journal of the American Medical Association (JAMA), 2019 Importance Chronic kidney disease (CKD) is the 16th leading cause of years of life lost worldwide. Appropriate screening, diagnosis, and management by primary care clinicians are necessary to prevent adverse CKD-associated outcomes, including ...
Teresa K. Chen +2 more
semanticscholar +1 more source
Relationship between lysosomal dyshomeostasis and progression of diabetic kidney disease
Cell Death and Disease, 2021 Lysosomes are organelles involved in cell metabolism, waste degradation, and cellular material circulation. They play a key role in the maintenance of cellular physiological homeostasis.
Man Wu +7 more
doaj +1 more source
Toxins, 2021 Chronic kidney disease (CKD) is a progressive loss of renal function. The gradual decline in kidney function leads to an accumulation of toxins normally cleared by the kidneys, resulting in uremia. Uremic toxins are classified into three categories: free
Y. J. Lim +4 more
semanticscholar +1 more source
Renal function assessment in adults with recurrent calcium kidney stone disease [PDF]
, 2012 The prevalence of nephrolihiasis and chronic kidney disease has risen over the past three decades, we sought to determine if person with a history of kidney stones have lower renal function relative to non stone formers.
Milladipour, Amir Hossein +1 more
core +1 more source
Klotho is regulated by transcription factor Sp1 in renal tubular epithelial cells
BMC Molecular and Cell Biology, 2020 Background Klotho is a multifunctional protein, which exists both in a membrane bound and a soluble form. In renal tubules, Klotho is involved in cell senescence, anti-oxidant response, and renal fibrosis, thus regulation of its expression is critical to
Yan Li +14 more
doaj +1 more source
European Heart Journal, 2021 Aims The complementary studies FIDELIO-DKD and FIGARO-DKD in patients with type 2 diabetes and chronic kidney disease (CKD) examined cardiovascular and kidney outcomes in different, overlapping stages of CKD.
R. Agarwal +10 more
semanticscholar +1 more source