Results 51 to 60 of about 2,456,607 (422)

Prevalence of chronic kidney disease in the United States.

open access: yesJournal of the American Medical Association (JAMA), 2007
CONTEXT The prevalence and incidence of kidney failure treated by dialysis and transplantation in the United States have increased from 1988 to 2004.
J. Coresh   +7 more
semanticscholar   +1 more source

Relationship between lysosomal dyshomeostasis and progression of diabetic kidney disease

open access: yesCell Death and Disease, 2021
Lysosomes are organelles involved in cell metabolism, waste degradation, and cellular material circulation. They play a key role in the maintenance of cellular physiological homeostasis.
Man Wu   +7 more
doaj   +1 more source

Wasting in chronic kidney disease [PDF]

open access: yesJournal of Cachexia, Sarcopenia and Muscle, 2011
Wasting/cachexia is prevalent among patients with chronic kidney disease (CKD). It is to be distinguished from malnutrition, which is defined as the consequence of insufficient food intake or an improper diet. Malnutrition is characterized by hunger, which is an adaptive response, whereas anorexia is prevalent in patients with wasting/cachexia.
Kamyar Kalantar-Zadeh   +8 more
openaire   +4 more sources

Chronic Kidney Disease

open access: yesJournal of Atherosclerosis and Thrombosis, 2014
Chronic kidney disease is a condition that affects thousands of children all over the world, compromising their health and quality of life. Recent epidemiological studies have provided evidence suggesting that the number of patients is expected to grow.
Mencarelli F., Busutti M., Montini G.
openaire   +4 more sources

An Australian Chronic Kidney Disease Biobank to Support Future Research

open access: yesOpen Journal of Bioresources, 2019
The Chronic Kidney Disease (CKD) Biobank is a repository for plasma, erythrocytes, serum, peripheral blood mononuclear cells (PBMCs), DNA, kidney core biopsies, and relevant clinical data.
Evan P. Owens   +4 more
doaj   +1 more source

Klotho is regulated by transcription factor Sp1 in renal tubular epithelial cells

open access: yesBMC Molecular and Cell Biology, 2020
Background Klotho is a multifunctional protein, which exists both in a membrane bound and a soluble form. In renal tubules, Klotho is involved in cell senescence, anti-oxidant response, and renal fibrosis, thus regulation of its expression is critical to
Yan Li   +14 more
doaj   +1 more source

Definition and classification of chronic kidney disease: a position statement from Kidney Disease: Improving Global Outcomes (KDIGO).

open access: yesKidney International, 2005
Chronic kidney disease (CKD) is a worldwide public health problem, with adverse outcomes of kidney failure, cardiovascular disease (CVD), and premature death.
A. Levey   +9 more
semanticscholar   +1 more source

Humanized Mouse Models of Systemic Lupus Erythematosus: Opportunities and Challenges

open access: yesFrontiers in Immunology, 2022
Animal models have played a crucial role in the understanding of the mechanisms and treatments of human diseases; however, owing to the large differences in genetic background and disease-specific characteristics, animal models cannot fully simulate the ...
Jiaxuan Chen   +10 more
doaj   +1 more source

Gout and risk of chronic kidney disease and nephrolithiasis meta-analysis of observational studies [PDF]

open access: yes, 2015
ntroduction To determine the prevalence of chronic kidney disease and nephrolithiasis in people with gout, and the association between gout and prevalent or incident chronic kidney disease and nephrolithiasis.
Belcher, J, Mallen, CD, Roddy, E
core   +2 more sources

Cardiovascular and kidney outcomes with finerenone in patients with type 2 diabetes and chronic kidney disease: the FIDELITY pooled analysis

open access: yesEuropean Heart Journal, 2021
Aims The complementary studies FIDELIO-DKD and FIGARO-DKD in patients with type 2 diabetes and chronic kidney disease (CKD) examined cardiovascular and kidney outcomes in different, overlapping stages of CKD.
R. Agarwal   +10 more
semanticscholar   +1 more source

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