Results 21 to 30 of about 54,330 (142)
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2007 Until recently, chronic wasting disease of cervids, the only prion disease affecting wildlife, was believed to be geographically concentrated to Colorado and Wyoming within the United States. However, increased surveillance has unveiled several additional pockets of CWD-infected deer and elk in 12 additional states and 2 Canadian provinces.
Sigurdson, C J, Aguzzi, A
+7 more sources
Mouse models of chronic wasting disease: A review
Frontiers in Virology, 2023 Animal models are essential tools for investigating and understanding complex prion diseases like chronic wasting disease (CWD), an infectious prion disease of cervids (elk, deer, moose, and reindeer). Over the past several decades, numerous mouse models
Makayla Cook +2 more
doaj +1 more source
Evolutionary Applications, 2020 Identifying the sources of ongoing and novel disease outbreaks is critical for understanding the diffusion of epizootic diseases. Identifying infection sources is difficult when few physical differences separate individuals with different origins ...
William L. Miller, W. David Walter
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Prion protein polymorphisms affect chronic wasting disease progression. [PDF]
PLoS ONE, 2011 Analysis of the PRNP gene in cervids naturally infected with chronic wasting disease (CWD) suggested that PRNP polymorphisms affect the susceptibility of deer to infection.
Chad J Johnson +6 more
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Acta virologica, 2011 Chronic wasting disease (CWD) is a prion disease of free-ranging and farmed ungulates (deer, elk, and moose) in North America and South Korea. First described by the late E.S. Williams and colleagues in northern Colorado and southern Wyoming in the 1970s, CWD has increased tremendously both in numerical and geographical distribution, reaching ...
Sabine, Gilch +5 more
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Ticks harbor and excrete chronic wasting disease prions
Scientific Reports, 2023 Chronic wasting disease (CWD) is a fatal neurodegenerative disease caused by infectious prions (PrPCWD) affecting cervids. Circulating PrPCWD in blood may pose a risk for indirect transmission by way of hematophagous ectoparasites acting as mechanical ...
H. N. Inzalaco +7 more
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Gene-Edited Cell Models to Study Chronic Wasting Disease
Viruses, 2022 Prion diseases are fatal infectious neurodegenerative disorders affecting both humans and animals. They are caused by the misfolded isoform of the cellular prion protein (PrPC), PrPSc, and currently no options exist to prevent or cure prion diseases ...
Simrika Thapa +5 more
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Erratum to: Wasting in chronic kidney disease [PDF]
Journal of Cachexia, Sarcopenia and Muscle, 2011 Erratum to: J Cachexia Sarcopenia Muscle (2011) 2:9–25 DOI 10.1007/s13539-011-0019-5 In the original publication the initial letters for author T. Alp Ikizler had been printed in reverse order.
Mak, Robert H +5 more
openaire +4 more sources
Prion, 2012 Transmissible spongiform encephalopathies (prion diseases) in animals may be associated with a zoonotic risk potential for humans as shown by the occurrence of variant Creutzfeldt-Jakob disease in the wake of the bovine spongiform encephalopathy epidemic.
Daus, Martin L., Beekes, Michael
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Chronic Wasting Disease Agents in Nonhuman Primates
Emerging Infectious Diseases, 2014 Chronic wasting disease is a prion disease of cervids. Assessment of its zoonotic potential is critical. To evaluate primate susceptibility, we tested monkeys from 2 genera.
Brent Race +5 more
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