Results 21 to 30 of about 59,618 (284)
A microfluidic biosensor for the diagnosis of chronic wasting disease
Microsystems & Nanoengineering, 2023 Cervids are affected by a neurologic disease that is always fatal to individuals and has population effects. This disease is called chronic wasting disease (CWD) and is caused by a misfolded prion protein.
Sura A. Muhsin +7 more
doaj +3 more sources
Chronic Wasting Disease and Potential Transmission to Humans
Emerging Infectious Diseases, 2004 Chronic wasting disease (CWD) of deer and elk is endemic in a tri-corner area of Colorado, Wyoming, and Nebraska, and new foci of CWD have been detected in other parts of the United States.
Ermias D. Belay +5 more
doaj +3 more sources
Chronic Wasting Disease Prion Strain Emergence and Host Range Expansion
Emerging Infectious Diseases, 2017 Human and mouse prion proteins share a structural motif that regulates resistance to common chronic wasting disease (CWD) prion strains. Successful transmission of an emergent strain of CWD prion, H95+, into mice resulted in infection. Thus, emergent CWD
Allen Herbst +4 more
doaj +2 more sources
, 2016 Chronic wasting disease (CWD) is a neurodegenerative disease caused by a prion that affects cervids including deer, elk and moose. At one time, CWD was an obscure illness that seemed to occur only in a small geographic area in northeastern Colorado and ...
openaire +3 more sources
Triggers and mechanisms of skeletal muscle wasting in chronic obstructive pulmonary disease. [PDF]
, 2013 Skeletal muscle wasting contributes to impaired exercise capacity, health-related quality of life and is an independent determinant of chronic obstructive pulmonary disease.
Langen, R.C.J. +4 more
core +1 more source
Evolutionary Applications, 2020 Identifying the sources of ongoing and novel disease outbreaks is critical for understanding the diffusion of epizootic diseases. Identifying infection sources is difficult when few physical differences separate individuals with different origins ...
William L. Miller, W. David Walter
doaj +1 more source
Prion protein polymorphisms affect chronic wasting disease progression. [PDF]
PLoS ONE, 2011 Analysis of the PRNP gene in cervids naturally infected with chronic wasting disease (CWD) suggested that PRNP polymorphisms affect the susceptibility of deer to infection.
Chad J Johnson +6 more
doaj +1 more source
Acta virologica, 2011 Chronic wasting disease (CWD) is a prion disease of free-ranging and farmed ungulates (deer, elk, and moose) in North America and South Korea. First described by the late E.S. Williams and colleagues in northern Colorado and southern Wyoming in the 1970s, CWD has increased tremendously both in numerical and geographical distribution, reaching ...
Sabine, Gilch +5 more
openaire +4 more sources
Ticks harbor and excrete chronic wasting disease prions
Scientific Reports, 2023 Chronic wasting disease (CWD) is a fatal neurodegenerative disease caused by infectious prions (PrPCWD) affecting cervids. Circulating PrPCWD in blood may pose a risk for indirect transmission by way of hematophagous ectoparasites acting as mechanical ...
H. N. Inzalaco +7 more
doaj +1 more source
Genetic variability of the prion protein gene (PRNP) in wild ruminants from Italy and Scotland [PDF]
, 2009 The genetics of the prion protein gene (PRNP) play a crucial role in determining the relative susceptibility to transmissible spongiform encephalopathies (TSEs) in several mammalian species.
Acutis, Pier Luigi +33 more
core +1 more source