Results 11 to 20 of about 54,330 (142)

Exposure Risk of Chronic Wasting Disease in Humans [PDF]

Viruses, 2020
The majority of human prion diseases are sporadic, but acquired disease can occur, as seen with variant Creutzfeldt–Jakob disease (vCJD) following consumption of bovine spongiform encephalopathy (BSE).
Satish K. Nemani, Jennifer L. Myskiw, Lise Lamoureux, Stephanie A. Booth, Valerie L. Sim   +4 more
doaj   +3 more sources

Prion shedding is reduced by chronic wasting disease vaccination. [PDF]

PLoS Pathogens
Chronic wasting disease (CWD) is a strictly fatal and highly contagious prion disease of wild and farmed cervids currently expanding in North America. Prion diseases are caused by conversion of the cellular prion protein to its pathological isoform PrPSc.
Hanaa Ahmed-Hassan, Dalia Abdelaziz, Yo-Ching Cheng, Kevin Low, Shirley Phan, Byron Kruger, Chimoné S Dalton, Lech Kaczmarczyk, Walker S Jackson, Sabine Gilch, Hermann M Schätzl   +10 more
doaj   +2 more sources

Genetic Variation and Strain Dynamics in Chronic Wasting Disease [PDF]

Viruses
Chronic wasting disease (CWD) is a prion disease of cervids marked by growing strain diversity and variation in host susceptibility. Central to this complexity are prion protein gene (Prnp) polymorphisms, which can modulate pathogenesis by altering the ...
Irina Zemlyankina, Melissa Razcon-Echeagaray, Gokhan Yilmaz, Kristen B. Gregg, Sabine Gilch, Samia Hannaoui   +5 more
doaj   +2 more sources

Susceptibilities of Nonhuman Primates to Chronic Wasting Disease

Emerging Infectious Diseases, 2009
Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy, or prion disease, that affects deer, elk, and moose. Human susceptibility to CWD remains unproven despite likely exposure to CWD-infected cervids.
Brent Race, Kimberly D. Meade-White, Michael W. Miller, Kent D. Barbian, Richard Rubenstein, Giuseppe LaFauci, Larisa Cervenakova, Cynthia Favara, Donald Gardner, Dan Long, Michael Parnell, James Striebel, Suzette A. Priola, Anne Ward, Elizabeth S. Williams, Richard Race, Bruce Chesebro   +16 more
doaj   +3 more sources

The Zoonotic Potential of Chronic Wasting Disease—A Review

Foods, 2023
Prion diseases are transmissible neurodegenerative disorders that affect humans and ruminant species consumed by humans. Ruminant prion diseases include bovine spongiform encephalopathy (BSE) in cattle, scrapie in sheep and goats and chronic wasting ...
Michael A. Tranulis, Morten Tryland
doaj   +5 more sources

A microfluidic biosensor for the diagnosis of chronic wasting disease

Microsystems & Nanoengineering, 2023
Cervids are affected by a neurologic disease that is always fatal to individuals and has population effects. This disease is called chronic wasting disease (CWD) and is caused by a misfolded prion protein.
Sura A. Muhsin, Amjed Abdullah, Estela kobashigawa, Muthana Al-Amidie, Sherri Russell, Michael Z. Zhang, Shuping Zhang, Mahmoud Almasri   +7 more
doaj   +3 more sources

Scrapie versus Chronic Wasting Disease in White-Tailed Deer [PDF]

Emerging Infectious Diseases
White-tailed deer are susceptible to scrapie (WTD scrapie) after oronasal inoculation with the classical scrapie agent from sheep. Deer affected by WTD scrapie are difficult to differentiate from deer infected with chronic wasting disease (CWD).
Zoe J. Lambert, Jifeng Bian, Eric D. Cassmann, M. Heather West Greenlee, Justin J. Greenlee   +4 more
doaj   +2 more sources

Chronic Wasting Disease and Potential Transmission to Humans

Emerging Infectious Diseases, 2004
Chronic wasting disease (CWD) of deer and elk is endemic in a tri-corner area of Colorado, Wyoming, and Nebraska, and new foci of CWD have been detected in other parts of the United States.
Ermias D. Belay, Ryan A. Maddox, Elizabeth S. Williams, Michael W. Miller, Pierluigi Gambetti, Lawrence B. Schonberger   +5 more
doaj   +3 more sources

Chronic wasting disease: Emerging prions and their potential risk. [PDF]

PLoS Pathogens, 2017
Samia Hannaoui, Hermann M Schatzl, Sabine Gilch   +2 more
doaj   +3 more sources

Association Study of the M132L Single Nucleotide Polymorphism With Susceptibility to Chronic Wasting Disease in Korean Elk: A Meta-Analysis

Frontiers in Veterinary Science, 2022
Chronic wasting disease (CWD) is a deleterious brain proteinopathy caused by a pathogenic form of prion protein (PrPSc), which is converted from a benign form of prion protein (PrPC) encoded by the prion protein gene (PRNP).
In-Soon Roh, Yong-Chan Kim, Yong-Chan Kim, Sae-Young Won, Sae-Young Won, Kyung-Je Park, Hoo-Chang Park, Ji-Yong Hwang, Hae-Eun Kang, Hyun-Joo Sohn, Byung-Hoon Jeong, Byung-Hoon Jeong   +11 more
doaj   +1 more source