Results 81 to 90 of about 122,977 (290)

Transformations to achieve the Sustainable Development Goals Includes the SDG Index and Dashboards. Sustainable Development Report 2019 [PDF]

, 2019
The Sustainable Development Report 2019 presents an updated SDG Index and Dashboards with a refined assessment of countries’ distance to SDG targets. The report has been successfully audited for the first time by the European Commission Joint Research ...
Fuller, G., Kroll, C., Lafortune, G., Sachs, J., Schmidt-Traub, G.   +4 more
core  

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source

Animal Industry News, 2009, Vol. 10, no. 1 [PDF]

, 2009
Newsletter produced by Department of Agriculture and Land Stewardship about the animal industry in ...

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Cryptosporidium, Enterocytozoon, and Cyclospora Infections in Pediatric and Adult Patients with Diarrhea in Tanzania. [PDF]

, 1999
Cryptosporidiosis, microsporidiosis, and cyclosporiasis were studied in four groups of Tanzanian inpatients: adults with AIDS-associated diarrhea, children with chronic diarrhea (of whom 23 of 59 were positive [+] for human immunodeficiency virus [HIV]),
Abel E. Msengi, Anders F. Jorgensen, Charles R. Sterling, Current WL, David A. Schwartz, David H. Mwakyusa, J. Peter Cegielski, John F. Madden, Karim Manji, L. Barth Reller, Loretta Gaido, MacKenzie W, Nime FA, Sara E. Miller, Scott McKee, Uma P. Pulipaka, Ynes R. Ortega   +16 more
core   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

The Economic Effects of Chronic Wasting Disease (CWD) in Wisconsin [PDF]

Wisconsin's 600,000 deer hunters will bear the brunt of the economic losses from chronic wasting disease (CWD) in the Wisconsin deer herd. Though studies have not been done to pinpoint these losses, under plausible assumptions, they could have amounted ...
Bishop, Richard C.
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Cancer anorexia: hypothalamic activity and its association with inflammation and appetite-regulating peptides in lung cancer [PDF]

, 2017
Background Energy homeostasis is mediated by the hypothalamus, whose inflammation-induced functional derangements contribute to the onset of anorexia in cancer.
Arezzo di Trifiletti, Asakawa, Ayres, Braun, Cangiano, Cooper, DeBoer, Eiler, Engineer, Ezeoke, Fearon, Friedman, Garcia, Gordon, Haehling, Iyer, Jiang, Kilpatrick, Kim, Kullmann, Laviano, Laviano, Laviano, Li, Mantovani, Matsuda, Molfino, Molfino, Molfino, Molfino, Molfino, Muscaritoli, Opara, Page, Purnell, Smeets, Smeets, Smeets, Sánchez-Lara, Torelli   +39 more
core   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Occurrence, Transmission, and Zoonotic Potential of Chronic Wasting Disease

Emerging Infectious Diseases, 2012
Chronic wasting disease (CWD) is a fatal, transmissible prion disease that affects captive and free-ranging deer, elk, and moose. Although the zoonotic potential of CWD is considered low, identification of multiple CWD strains and the potential for agent
Samuel E. Saunders, Shannon L. Bartelt-Hunt, Jason C. Bartz   +2 more
doaj   +1 more source